WVU cancer researcher and Assistant Professor of Pharmaceutical Sciences Wei Du, MD, PhD, teamed up with researchers from Cincinnati Children’s Hospital Medical Center to focus on improving outcomes and reducing side effects of traditional stem cell transplant. Their work was recently published in Leukemia, one of the top journals in hematology.
The studies identify an innovative drug that targets Cdc42, a member of one of the Rho GTPase family, which increases bone marrow accessibility and therefore improves stem cell transplant outcome. This project is an extension of previous research in the field of Rho GTPase family in hematopoiesis and is intended to address the urgent and important need for stem cell transplantation. Dr. Du’s work offers a novel preparative regimen for stem cell transplantation in treating bone marrow failure and other blood diseases. They are currently working on establishing improved methods for blood stem cell harvest and transplantation that could significantly impact future stem cell therapies for patients with leukemia and other blood cancers.
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Two Studies Describe Improved Approach to Bone Marrow Transplant - Cincinnati Children's Newsroom
“Vaporized: America’s E-Cigarette Addiction,” a comprehensive look inside the rapidly growing and highly controversial vaping industry, a market expected to hit $9 billion by the end of 2019.
The Department of Diagnostic Sciences has developed a team of specialists aimed at raising awareness about oral cancer. The efforts include educating the public about the causes of oral cancer while promoting prevention and regular oral exams. In addition, the team maintains an active biopsy service staffed by pathologists trained specifically in the diagnosis of tumors of the mouth.
Some cancers are difficult to treat due to where they appear in the body. For some abdominal cancers, intravenous chemotherapy may not work because drugs flowing through the whole body don’t penetrate into the peritoneal cavity – the space surrounding your abdominal organs.