WVU cancer researcher and Assistant Professor of Pharmaceutical Sciences Wei Du, MD, PhD, teamed up with researchers from Cincinnati Children’s Hospital Medical Center to focus on improving outcomes and reducing side effects of traditional stem cell transplant. Their work was recently published in Leukemia, one of the top journals in hematology.
The studies identify an innovative drug that targets Cdc42, a member of one of the Rho GTPase family, which increases bone marrow accessibility and therefore improves stem cell transplant outcome. This project is an extension of previous research in the field of Rho GTPase family in hematopoiesis and is intended to address the urgent and important need for stem cell transplantation. Dr. Du’s work offers a novel preparative regimen for stem cell transplantation in treating bone marrow failure and other blood diseases. They are currently working on establishing improved methods for blood stem cell harvest and transplantation that could significantly impact future stem cell therapies for patients with leukemia and other blood cancers.
In the News:
Two Studies Describe Improved Approach to Bone Marrow Transplant - Cincinnati Children's Newsroom
Cervical cancer rates are higher among women in Appalachia due to a variety of factors ranging from health policy to biology. Next month, epidemiologist and cancer prevention researcher Electra Paskett, Ph.D., will visit the WVU Health Sciences Center to explain how these factors can help identify possible interventions to reverse this trend.
The Council for Women's Concerns is accepting nominations for the Mary Catherine Buswell Award. This accolade, established in 1978, honors a person who has shown a dedication to the advancement of women. The award winner will receive $500 for travel, supplies, salary supplement or any other use commensurate with WVU policies. Nominations must be submitted by March 1.