Publications of Kathy M. Brundage, PhD.

SOX9 inhibits beta-TrCP-mediated protein degradation to promote nuclear GLI1 expression and cancer stem cell properties.
Deng W, Vanderbilt DB, Lin CC, Martin KH, Brundage KM, Ruppert JM.
J Cell Sci. 2015;128(6):1123-1138.


Kruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival.
Lin CC, Sharma SB, Farrugia MK, McLaughlin SL, Ice RJ, Loskutov YV, Pugacheva EN, Brundage KM, Chen D, Ruppert JM.
Oncogenesis. 2015;4:e155

PMCID-In process.

SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma.
Luanpitpong S, Li J, Manke A, Brundage KM, Ellis E, McLaughlin SL, Angsutararux P, Chanthra N, Voronkova M, Chen YC, Wang L, Chanvorachote P, Pei M, Issaragrisil S, Rojanasakul Y.
Oncogene. 2015; [Epub ahead of print]

PMC Journal - In Process.

Metalloproteinase dependent reduction of cell surface cluster determinants upon the induction of apoptosis.
Magro A, Magro A, Shrestha S, Brundage KM, Rankin G.
Int J Oncol. 2014;44(5):1539-1550.


microRNAs-206 and -21 cooperate to promote RAS-ERK signaling by suppressing the translation of RASA1 and SPRED1.
Sharma SB, Lin CC, Farrugia MK, McLaughlin SL, Ellis EJ, Brundage KM, Salkeni MA, Ruppert JM.
Mol Cell Biol. 2014;34(22):4143-4164.


Sibling donor and recipient immune modulation with atorvastatin for the prophylaxis of acute graft-versus-host disease.
Hamadani M, Gibson LF, Remick SC, Wen S, Petros WP, Tse WW, Brundage KM, Vos JA, Cumpston AD, Bunner P, Craig M.
J Clin Oncol. 2013;31(35):4416-4423.


Prenatal cadmium exposure alters postnatal immune cell development and function.
Hanson ML, Holaskova I, Elliott M, Brundage KM, Schafer R, Barnett JB.
Toxicol Appl Pharmacol. 2012;261(2):196-203.


Early postnatal ozone exposure alters rat nodose and jugular sensory neuron development.
Zellner LC, Brundage KM, Hunter DD, Dey RD.
Toxicol Environ Chem. 2011;93(10):2055-2071.


The role of calcium release activated calcium channels in osteoclast differentiation.
Zhou Y, Lewis TL, Robinson LJ, Brundage KM, Schafer R, Martin KH, Blair HC, Soboloff J, Barnett JB.
J Cell Physiol. 2011;226(4):1082-1089.


Evaluating macrophages in immunotoxicity testing.
Barnett JB, Brundage KM.
Methods Mol Biol. 2010;598:75-94.

Subcellular localization of the amide class herbicide 3,4-dichloropropionanilide (DCPA) in T cells and hepatocytes.
Hanson ML, Peer CJ, Brundage RA, Callery PS, Brundage KM, Schafer R, Eremin S, Barnett JB.
J Toxicol Environ Health A. 2010;73(1):1-4.


Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/beta-catenin signaling in the thymus resulting in altered thymocyte development.
Hanson ML, Brundage KM, Schafer R, Tou JC, Barnett JB.
Toxicol Appl Pharmacol. 2010;242(2):136-145.


Scalable analysis of flow cytometry data using R/Bioconductor.
Klinke DJ, Brundage KM.
Cytometry A. 2009;75(8):699-706.


Modulating temporal control of NF-kappaB activation: implications for therapeutic and assay selection.
Klinke DJ, Ustyugova IV, Brundage KM, Barnett JB.
Biophys J. 2008;94(11):4249-4259.


3,4-Dichloropropionanilide (DCPA) inhibits T-cell activation by altering the intracellular calcium concentration following store depletion.
Lewis TL, Brundage KM, Brundage RA, Barnett JB.
Toxicol Sci. 2008;103(1):97-107.

Developmental immunotoxicity of atrazine in rodents.
Rowe AM, Brundage KM, Barnett JB.
Basic Clin Pharmacol Toxicol. 2008;102(2):139-145.

A review of the immunotoxicity of the pesticide 3,4-dichloropropionanalide.
Salazar KD, Ustyugova IV, Brundage KM, Barnett JB, Schafer R.
J Toxicol Environ Health B Crit Rev. 2008;11(8):630-645.

In vitro atrazine-exposure inhibits human natural killer cell lytic granule release.
Rowe AM, Brundage KM, Barnett JB.
Toxicol Appl Pharmacol. 2007;221(2):179-188.


3,4-dichloropropionaniline suppresses normal macrophage function.
Ustyugova IV, Frost LL, Van Dyke K, Brundage KM, Schafer R, Barnett JB.
Toxicol Sci. 2007;97(2):364-374.

Immunomodulatory effects of maternal atrazine exposure on male Balb/c mice.
Rowe AM, Brundage KM, Schafer R, Barnett JB.
Toxicol Appl Pharmacol. 2006;214(1):69-77.


Propanil exposure induces delayed but sustained abrogation of cell-mediated immunity through direct interference with cytotoxic T-lymphocyte effectors.
Sheil JM, Frankenberry MA, Schell TD, Brundage KM, Barnett JB.
Environ Health Perspect. 2006;114(7):1059-1064.


Regulation of polymeric immunoglobulin receptor expression by reovirus.
Pal K, Kaetzel CS, Brundage KM, Cunningham CA, Cuff CF.
J Gen Virol. 2005;86(Pt 8):2347-2357.

Altered AP-1 (activating protein-1) activity and c-jun activation in T cells exposed to the amide class herbicide 3,4-dichloropropionanilide (DCPA).
Brundage KM, Schafer R, Barnett JB.
Toxicol Sci. 2004;79(1):98-105.

The amide class herbicide 3,4-dichloropropionanilide (DCPA) alters the mobility of hydrocarbon chains in T-lymphocyte but not macrophage membranes.
Brundage KM, Barnett JB, Mahaney JE.
J Toxicol Environ Health A. 2003;66(23):2253-2265.