Publications of Patrick S. Callery, PhD.

Regulation of apoptosis by Bcl-2 cysteine oxidation in human lung epithelial cells.
Luanpitpong S, Chanvorachote P, Stehlik C, Tse WW, Callery PS, Wang LY, Rojanasakul Y.
Mol Biol Cell. 2013;24(6):858-869.

PMC3596255.

Localized delivery of chemotherapy to the cervix for radiosensitization.
Hodge LS, Downs LS, Jr., Chura JC, Thomas SG, Callery PS, Soisson AP, Kramer P, Wolfe SS, Tracy TS.
Gynecol Oncol. 2012;127(1):121-125.


Glutathione conjugation of busulfan produces a hydroxyl radical-trapping dehydroalanine metabolite.
Peer CJ, Younis IR, Leonard SS, Gannett PM, Minarchick VC, Kenyon AJ, Rojanasakul Y, Callery PS.
Xenobiotica. 2012;42(12):1170-1177.


Cysteine S-conjugate beta-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents.
Cooper AJ, Krasnikov BF, Niatsetskaya ZV, Pinto JT, Callery PS, Villar MT, Artigues A, Bruschi SA.
Amino Acids. 2011;41(1):7-27.

PMC2898922.

Reversible and irreversible protein glutathionylation: biological and clinical aspects.
Cooper AJ, Pinto JT, Callery PS.
Expert Opin Drug Metab Toxicol. 2011;

PMC3116085.

Time-dependent slowly-reversible inhibition of monoamine oxidase A by N-substituted 1,2,3,6-tetrahydropyridines.
Wichitnithad W, O'Callaghan JP, Miller DB, Train BC, Callery PS.
Bioorg Med Chem. 2011;19(24):7482-7492.


Effects of different carboxylic ester spacers on chemical stability, release characteristics, and anticancer activity of mono-PEGylated curcumin conjugates.
Wichitnithad W, Nimmannit U, Callery PS, Rojsitthisak P.
J Pharm Sci. 2011;100(12):5206-5218.


Subcellular localization of the amide class herbicide 3,4-dichloropropionanilide (DCPA) in T cells and hepatocytes.
Hanson ML, Peer CJ, Brundage RA, Callery PS, Brundage KM, Schafer R, Eremin S, Barnett JB.
J Toxicol Environ Health A. 2010;73(1):1-4.

PMC2888467.

Identification of isobaric product ions in electrospray ionization mass spectra of fentanyl using multistage mass spectrometry and deuterium labeling.
Wichitnithad W, McManus TJ, Callery PS.
Rapid Commun Mass Spectrom. 2010;24(17):2547-2553.


Diabetic cardiomyopathy-associated dysfunction in spatially distinct mitochondrial subpopulations.
Dabkowski ER, Williamson CL, Bukowski VC, Chapman RS, Leonard SS, Peer CJ, Callery PS, Hollander JM.
Am J Physiol Heart Circ Physiol. 2009;296(2):H359-H369.

PMC2643887.

Potential biomarkers of smoked fentanyl utilizing pyrolysis gas chromatography-mass spectrometry.
Nishikawa RK, Bell SC, Kraner JC, Callery PS.
J Anal Toxicol. 2009;33(8):418-422.


Influence of pH on the dissolution of folic acid supplements.
Younis IR, Stamatakis MK, Callery PS, Meyer-Stout PJ.
Int J Pharm. 2009;367(1-2):97-102.


Metabolism of the cysteine S-conjugate of busulfan involves a {beta}-lyase reaction.
Cooper AJ, Younis IR, Niatsetskaya ZV, Krasnikov BF, Pinto JT, Petros WP, Callery PS.
Drub Metab Dispos. 2008;36:1546-1552.

PMC2587289.

Direct injection mass spectrometric confirmation of multiple drugs in overdose cases from postmortem blood using electrospray ionization-tandem mass spectrometry and MS(3).
Peer CJ, Clay DJ, Glover HL, Renninger KL, Kraner JC, Callery PS.
J Anal Toxicol. 2008;32(8):709-714.


Trace evidence of trans-phenylpropene as a marker of smoked methamphetamine.
Shakleya DM, Plumley AE, Kraner JC, Bell SC, Callery PS.
J Anal Toxicol. 2008;32(8):705-708.


Dehydroalanine analog of glutathione: an electrophilic busulfan metabolite that binds to human glutathione S-transferase A1-1.
Younis IR, Elliott M, Peer CJ, Cooper AJ, Pinto JT, Konat GW, Kraszpulski M, Petros WP, Callery PS.
J Pharmacol Exp Ther. 2008;327(3):770-776.

PMC2678891.

Esterase inhibition attribute of grapefruit juice leading to a new drug interaction.
Li P, Callery PS, Gan LS, Balani SK.
Drub Metab Dispos. 2007;35(7):1023-1031.


Esterase inhibition by grapefruit juice flavonoids leading to a new drug interaction.
Li P, Callery PS, Gan LS, Balani SK.
Drub Metab Dispos. 2007;35(7):1203-1208.


Direct-injection mass spectrometric method for the rapid identification of fentanyl and norfentanyl in postmortem urine of six drug-overdose cases.
Peer CJ, Shakleya DM, Younis IR, Kraner JC, Callery PS.
J Anal Toxicol. 2007;31(8):515-521.


Thermal degradation analysis of amino acids in fingerprint residue by pyrolysis GC-MS to develop new latent fingerprint developing reagents.
Richmond-Aylor A, Bell SC, Callery PS, Morris K.
J Forensic Sci. 2007;52(2):380-382.


Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation.
Moungjaroen J, Nimmannit U, Callery PS, Wang LY, Azad N, Lipipun V, Chanvorachote P, Rojanasakul Y.
J Pharmacol Exp Ther. 2006;319(3):1062-1069.


Epoxidation of the methamphetamine pyrolysis product, trans-phenylpropene, to trans-phenylpropylene oxide by CYP enzymes and stereoselective glutathione adduct formation.
Sanga M, Younis IR, Tirumalai PS, Bland TM, Banaszewska M, Konat GW, Tracy TS, Gannett PM, Callery PS.
Toxicol Appl Pharmacol. 2006;211(2):148-156.


Identification of N,N-dimethylamphetamine formed by methylation of methamphetamine in formalin-fixed liver tissue by multistage mass spectrometry.
Shakleya DM, Kraner JC, Kaplan JA, Gannett PM, Callery PS.
Forensic Sci Int. 2006;157(2-3):87-92.


Validation of a headspace GC method for the analysis of a pyrolytic product of methamphetamine in urine.
Shakleya DM, Kraner JC, Clay DJ, Callery PS, Bell SC.
J Anal Toxicol. 2006;30(8):559-562.


CYP2C-catalyzed delta9-tetrahydrocannabinol metabolism: kinetics, pharmacogenetics and interaction with phenytoin.
Bland TM, Haining RL, Tracy TS, Callery PS.
Biochem Pharmacol. 2005;70(7):1096-1103.


Identification of anhydroecgonine ethyl ester in the urine of a drug overdose victim.
Myers AL, Williams HE, Kraner JC, Callery PS.
J Forensic Sci. 2005;50(6):1481-1485.


Potential marker for smoked methamphetamine hydrochloride based on a gas chromatography-mass spectrometry quantification method for trans-phenylpropene.
Shakleya DM, Tarr SG, Kraner JC, Clay DJ, Callery PS.
J Anal Toxicol. 2005;29(6):552-555.


Methylation of 3,4-methylenedioxymethamphetamine in formalin-fixed human liver tissue.
Shakleya DM, Kraner JC, Kaplan JA, Callery PS.
J Anal Toxicol. 2005;29(7):715-717.


Conversion of methamphetamine to N-methyl-methamphetamine in formalin solutions.
Tirumalai PS, Shakleya DM, Gannett PM, Callery PS, Bland TM, Tracy TS.
J Anal Toxicol. 2005;29(1):48-53.


Comparison of magnesium sulfate and sodium sulfate for removal of water from pesticide extracts of foods.
Schenck FJ, Callery PS, Gannett PM, Daft JR, Lehotay SJ.
J AOAC Int. 2002;85(5):1177-1180.


Plasma pharmacokinetics and tissue distribution in CD2F1 mice of Pc4 (NSC 676418), a silicone phthalocyanine photodynamic sensitizing agent.
Egorin MJ, Zuhowski EG, Sentz DL, Dobson JM, Callery PS, Eiseman JL.
Cancer Chemother Pharmacol. 1999;44(4):283-294.


Metabolism of 17-(allylamino)-17-demethoxygeldanamycin (NSC 330507) by murine and human hepatic preparations.
Egorin MJ, Rosen DM, Wolff JH, Callery PS, Musser SM, Eiseman JL.
Cancer Res. 1998;58(11):2385-2396.


Tumor-targeted apoptosis by a novel spermine analogue, 1,12-diaziridinyl-4,9-diazadodecane, results in therapeutic efficacy and enhanced radiosensitivity of human prostate cancer.
Eiseman JL, Rogers FA, Guo Y, Kauffman J, Sentz DL, Klinger MF, Callery PS, Kyprianou N.
Cancer Res. 1998;58(21):4864-4870.


Aminoalkylaziridines as substrates and inhibitors of lysyl oxidase: specific inactivation of the enzyme by N-(5-aminopentyl)aziridine.
Nagan N, Callery PS, Kagan HM.
Front Biosci. 1998;3:A23-A26.


Chromatographic methods of analysis of antibiotics in milk.
Schenck FJ, Callery PS.
J Chromatogr A. 1998;812(1-2):99-109.


In vitro metabolism by mouse and human liver preparations of halomon, an antitumor halogenated monoterpene.
Egorin MJ, Rosen DM, Benjamin SE, Callery PS, Sentz DL, Eiseman JL.
Cancer Chemother Pharmacol. 1997;41(1):9-14.


Comparative molecular field analysis-based predictive model of structure-function relationships of polyamine transport inhibitors in L1210 cells.
Li Y, MacKerell AD, Jr., Egorin MJ, Ballesteros MF, Rosen DM, Wu YY, Blamble DA, Callery PS.
Cancer Res. 1997;57(2):234-239.


Plasma pharmacokinetics, bioavailability, and tissue distribution in CD2F1 mice of halomon, an antitumor halogenated monoterpene isolated from the red algae Portieria hornemannii.
Egorin MJ, Sentz DL, Rosen DM, Ballesteros MF, Kearns CM, Callery PS, Eiseman JL.
Cancer Chemother Pharmacol. 1996;39(1-2):51-60.


Plasma pharmacokinetics and urinary excretion of the polyamine analogue 1, 19-bis(ethylamino)-5, 10, 15-triazanonadecane in CD2F1 mice.
Eiseman JL, Yuan ZM, Eddington ND, Sentz DL, Callery PS, Egorin MJ.
Cancer Chemother Pharmacol. 1996;38(1):13-20.


Synthesis and antitumor evaluation of a highly potent cytotoxic DNA cross-linking polyamine analogue, 1,12-diaziridinyl-4,9-diazadodecane.
Li Y, Eiseman JL, Sentz DL, Rogers FA, Pan SS, Hu LT, Egorin MJ, Callery PS.
J Med Chem. 1996;39(1):339-341.


Cytotoxic activity of N1- and N8-aziridinyl analogs of spermidine.
Yuan ZM, Rosen DM, Egorin MJ, Callery PS.
Biochem Pharmacol. 1994;47(9):1587-1592.


Cellular pharmacology of N1- and N8-aziridinyl analogues of spermidine.
Yuan ZM, Egorin MJ, Rosen DM, Simon MA, Callery PS.
Cancer Res. 1994;54(3):742-748.


Alkylamides as inducers of human leukemia cell differentiation: a quantitative structure-activity relationship study using comparative molecular field analysis.
Harpalani AD, Snyder SW, Subramanyam B, Egorin MJ, Callery PS.
Cancer Res. 1993;53(4):766-771.


Isotopically sensitive regioselectivity in the oxidative deamination of a homologous series of diamines catalyzed by diamine oxidase.
Callery PS, Subramanyam B, Yuan ZM, Pou S, Geelhaar LA, Reynolds KA.
Chem Biol Interact. 1992;85(1):15-26.


Active-site directed irreversible inhibition of diamine oxidase by a homologous series of aziridinylalkylamines.
Conner JW, Yuan ZM, Callery PS.
Biochem Pharmacol. 1992;44(6):1229-1232.


Alkylation of DNA with aziridine produced during the hydrolysis of N,N',N''-triethylenethiophosphoramide.
Musser SM, Pan SS, Egorin MJ, Kyle DJ, Callery PS.
Chem Res Toxicol. 1992;5(1):95-99.


Induction of human leukemia cell differentiation by regiospecifically acetylated spermidines.
Snyder SW, Egorin MJ, Callery PS.
Biochem Biophys Res Commun. 1991;180(2):591-596.


Supercritical fluid chromatography/chemical ionization/mass spectrometry of some anticancer drugs in a thermospray ion source.
Musser SM, Callery PS.
Biomed Environ Mass Spectrom. 1990;19(6):348-352.


Effects of the monoamine oxidase inhibitor, tranylcypromine, on induction of HL60 cell differentiation by hexamethylene bisacetamide and N-acetyl-1,6-diaminohexane.
Snyder SW, Egorin MJ, Zuhowski EG, Schimpff EC, Callery PS.
Cancer Commun. 1990;2(7):231-236.


Derivatization of N-methyl and cyclic amino acids with dimethylformamide dimethyl acetal.
Grubb MF, Callery PS.
J Chromatogr. 1989;469:191-196.


Liquid chromatography-thermospray mass spectrometry of DNA adducts formed with mitomycin C, porfiromycin and thiotepa.
Musser SM, Pan SS, Callery PS.
J Chromatogr. 1989;474(1):197-207.


A nuclear magnetic resonance (NMR) method for the determination of the cis/trans isomeric content of chlorprothixene.
Rosler KH, Wright J, Fox KM, Waters RM, Callery PS.
Pharm Res. 1989;6(8):706-708.


An active, aldehydic metabolite of the cell-differentiating agent hexamethylene bisacetamide.
Subramanyam B, Callery PS, Egorin MJ, Snyder SW, Conley BA.
Drub Metab Dispos. 1989;17(4):398-401.


A cyclic imine intermediate in the in vitro metabolic conversion of 1,6-diaminohexane to 6-aminohexanoic acid and caprolactam.
Subramanyam B, Callery PS, Geelhaar LA, Egorin MJ.
Xenobiotica. 1989;19(1):33-42.


Metabolic conversion of 2-propylpentanal acetals to valproic acid in vitro. Model prodrugs of carboxylic acid agents.
Vicchio D, Callery PS.
Drub Metab Dispos. 1989;17(5):513-517.


Involvement of monoamine oxidase and diamine oxidase in the metabolism of the cell differentiating agent hexamethylene bisacetamide (HMBA).
Conley BA, Callery PS, Egorin MJ, Subramanyam B, Geelhaar LA, Pan SS.
Life Sci. 1988;43(9):793-800.


Metabolism of hexamethylene bisacetamide and its metabolites in leukemic cells.
Egorin MJ, Snyder SW, Cohen AS, Zuhowski EG, Subramanyam B, Callery PS.
Cancer Res. 1988;48(7):1712-1716.


Induction of differentiation of human promyelocytic leukemia cells (HL60) by metabolites of hexamethylene bisacetamide.
Snyder SW, Egorin MJ, Geelhaar LA, Hamburger AW, Callery PS.
Cancer Res. 1988;48(13):3613-3616.


Silylated N,O-ketals from the reaction of ketones with N-trimethylsilylimidazole.
Andrews PA, Bachur NR, Musser SM, Wright J, Callery PS.
J Chromatogr. 1987;419:271-274.


Gas chromatographic analysis of metabolites of the cell differentiating agent hexamethylene bisacetamide.
Egorin MJ, Zuhowski EG, Nayar MS, Callery PS.
J Chromatogr. 1987;415(1):148-155.


Plasma pharmacokinetics and urinary excretion of hexamethylene bisacetamide metabolites.
Egorin MJ, Zuhowski EG, Cohen AS, Geelhaar LA, Callery PS, Van Echo DA.
Cancer Res. 1987;47(22):6142-6146.


The chemical reduction of diaziquone: products and free radical intermediates.
Gutierrez PL, Balachandran Nayar MS, Nardino R, Callery PS.
Chem Biol Interact. 1987;64(1-2):23-37.


Gas chromatographic-mass spectrometric determination of tryptophan transaminase-catalyzed deuterium exchange.
Vicchio D, Speedie MK, Callery PS.
J Chromatogr. 1987;415(1):104-109.


Identification of metabolites of the cell-differentiating agent hexamethylene bisacetamide in humans.
Callery PS, Egorin MJ, Geelhaar LA, Nayar MS.
Cancer Res. 1986;46(10):4900-4903.


1-Piperideine as an in vivo precursor of the gamma-aminobutyric acid homologue 5-aminopentanoic acid.
Callery PS, Geelhaar LA.
J Neurochem. 1985;45(3):946-948.


Superoxide radical reactions with anthracycline antibiotics.
Nakazawa H, Andrews PA, Callery PS, Bachur NR.
Biochem Pharmacol. 1985;34(4):481-490.


Biosynthesis of 5-aminopentanoic acid and 2-piperidone from cadaverine and 1-piperideine in mouse.
Callery PS, Geelhaar LA.
J Neurochem. 1984;43(6):1631-1634.


Putrescine metabolism: enzymatic formation and non-enzymatic isotope exchange of delta1-pyrroline.
Callery PS, Nayar MS, Geelhaar LA.
Biomed Mass Spectrom. 1984;11(3):118-120.


Qualitative analysis of trimethylsilylated daunosamine and N-alkylated analogs by gas chromatography--mass spectrometry.
Andrews PA, Callery PS, Chou FT, May ME, Bachur NR.
Anal Biochem. 1982;126(2):258-267.


Pyrrolines as prodrugs of gamma-aminobutyric acid analogues.
Callery PS, Geelhaar LA, Nayar MS, Stogniew M, Rao KG.
J Neurochem. 1982;38(4):1063-1067.


Intermolecular and intramolecular isotope effects in the deamination of putrescine catalyzed by diamine oxidase.
Callery PS, Nayar MS, Jakubowski EM, Stogniew M.
Experientia. 1982;38(4):431-433.


Applications of deuterium labeling in the study of the in vitro conversion of delta 1-pyrroline to 4-aminobutanoic acid and 2-pyrrolidinone.
Callery PS, Nayar MS, Geelhaar LA, Stogniew M, Jakubowski EM.
Biomed Mass Spectrom. 1980;7(11-12):525-528.


Detection of the in vivo conversion of 2-pyrrolidinone to gamma-aminobutyric acid in mouse brain.
Callery PS, Stogniew M, Geelhaar LA.
Biomed Mass Spectrom. 1979;6(1):23-26.


Synthesis and preliminary biological studies of 4- and 5-[2-hydroxy-3-(isopropylamino)propoxy]benzimidazoles: selective beta2 adrenergic blocking agents.
Crooks CR, Wright J, Callery PS, Moreton JE.
J Med Chem. 1979;22(2):210-214.


Membrane transport of Tc-99m-labeled radiopharmaceuticals, I. Brain uptake by passive transport.
Loberg MD, Corder EH, Fields AT, Callery PS.
J Nucl Med. 1979;20(11):1181-1188.


2-pyrrolidinone--a cyclization product of gamma-aminobutyric acid detected in mouse brain.
Callery PS, Geelhaar LA, Stogniew M.
Biochem Pharmacol. 1978;27(16):2061-2063.


N-Methylation of benzimidazole by catechol-O-methyltransferase.
Arnett CD, Callery PS, Zenker N.
Biochem Pharmacol. 1977;26(5):377-380.


Thermal decomposition of 1,3-dimethyl derivative of phenobarbital in trimethylanilinium hydroxide.
Callery PS, Leslie J.
J Pharm Sci. 1977;66(4):578-580.


In vitro stereoselective metabolism of the psychotomimetic amine, 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane. An apparent enantiomeric interaction.
McGraw NP, Callery PS, Castagnoli N, Jr.
J Med Chem. 1977;20(2):185-189.


Letter: Decomposition of 1,3-dimethylphenobarbital in trimethylanilinium hydroxide.
Callery PS, Leslie J.
Clin Chem. 1976;22(6):926-927.


Tissue distribution of technetium-99m and carbon-14 labeled N-(2,6-dimethylphenylcarbamoylmethyl)iminodiacetic acid.
Callery PS, Faith WC, Loberg MD, Fields AT, Harvey EB, Cooper MD.
J Med Chem. 1976;19(7):962-964.


A convenient synthesis of quinones from hydroquinone dimethyl ethers. Oxidative demethylation with ceric ammonijm nitrate.
Jacob P, III, Callery PS, Shulgin AT, Castagnoli N, Jr.
J Org Chem. 1976;41(22):3627-3629.


Development of new radiopharmaceuticals based on N-substitution of iminodiacetic acid.
Loberg MD, Cooper M, Harvey E, Callery PS, Faith W.
J Nucl Med. 1976;17(7):633-638.


Application of chemical ionization mass spectrometry to the study of stereoselective in vitro metabolism of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane.
Weinkam RJ, Gal J, Callery PS, Castagnoli N, Jr.
Anal Chem. 1976;48(1):203-209.


Stereochemical aspects and metabolite formation in the in vivo metabolism of the psychotomimetic amine, 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane.
Matin SB, Callery PS, Zweig JS, O'Brien A, Rapoport R, Castagnoli N, Jr.
J Med Chem. 1974;17(8):877-882.