Publications of Timothy Eubank, PhD

New class of 8-aryl-7-deazaguanine cell permeable fluorescent probes.
Dhimitruka I, Eubank TD, Gross AC, Khramtsov VV.
Bioorg Med Chem Lett. 2015;25(20):4593-4596.

PMC4592842.

Comparison of azithromycin and amoxicillin prior to dental implant placement: an exploratory study of bioavailability and resolution of postoperative inflammation.
Escalante MG, Eubank TD, Leblebicioglu B, Walters JD.
J Periodontol. 2015;1-17.

PMC4626269.

Social stress-enhanced severity of Citrobacter rodentium-induced colitis is CCL2-dependent and attenuated by probiotic Lactobacillus reuteri.
Mackos AR, Galley JD, Eubank TD, Easterling RS, Parry NM, Fox JG, Lyte M, Bailey MT.
Mucosal Immunol. 2015; [Epub ahead of print]


Follistatin-like 3 is a mediator of exercise-driven bone formation and strengthening.
Nam J, Perera P, Gordon R, Jeong YH, Blazek AD, Kim DG, Tee BC, Sun Z, Eubank TD, Zhao Y, Lablebecioglu B, Liu S, Litsky A, Weisleder NL, Lee BS, Butterfield T, Schneyer AL, Agarwal S.
Bone. 2015;78:62-70.

PMC4466155.

Detection of nitric oxide production in cell cultures by luciferin-luciferase chemiluminescence.
Woldman YY, Eubank TD, Mock AJ, Stevens NC, Varadharaj S, Turco J, Gavrilin MA, Branchini BR, Khramtsov VV.
Biochem Biophys Res Commun. 2015;465(2):232-238.


Involvement of tumor macrophage HIFs in chemotherapy effectiveness: mathematical modeling of oxygen, pH, and glutathione.
Chen D, Bobko AA, Gross AC, Evans R, Marsh CB, Khramtsov VV, Eubank TD, Friedman A.
PLoS One. 2014;9(10):e107511

PMC4189793.

A sympathetic role for the pancreas in tumor progression?
Eubank TD.
Brain Behav Immun. 2014;40:38-39.


Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer.
Forget MA, Voorhees JL, Cole SL, Dakhlallah D, Patterson IL, Gross AC, Moldovan L, Mo X, Evans R, Marsh CB, Eubank TD.
PLoS One. 2014;9(6):e98623

PMC4043882.

Cytokine concentrations in the cerebrospinal fluid of great danes with cervical spondylomyelopathy.
Martin-Vaquero P, da Costa RC, Moore SA, Gross AC, Eubank TD.
J Vet Intern Med. 2014;28(4):1268-1274.

PMC4169188.

Preferential, enhanced breast cancer cell migration on biomimetic electrospun nanofiber 'cell highways'.
Nelson MT, Short A, Cole SL, Gross AC, Winter J, Eubank TD, Lannutti JJ.
BMC Cancer. 2014;14:825

PMC4236463.

In vivo proton-electron double-resonance imaging of extracellular tumor pH using an advanced nitroxide probe.
Samouilov A, Efimova OV, Bobko AA, Sun Z, Petryakov S, Eubank TD, Trofimov DG, Kirilyuk IA, Grigor'ev IA, Takahashi W, Zweier JL, Khramtsov VV.
Anal Chem. 2014;86(2):1045-1052.

PMC3981471.

Phosphonated trityl probes for concurrent in vivo tissue oxygen and pH monitoring using electron paramagnetic resonance-based techniques.
Dhimitruka I, Bobko AA, Eubank TD, Komarov DA, Khramtsov VV.
J Am Chem Soc. 2013;135(15):5904-5910.

PMC3982387.

Peri-implant versus periodontal wound healing.
Emecen-Huja P, Eubank TD, Shapiro V, Yildiz V, Tatakis DN, Leblebicioglu B.
J Clin Periodontol. 2013;40(8):816-824.

PMC3725126.

Macrophage microvesicles induce macrophage differentiation and miR-223 transfer.
Ismail N, Wang Y, Dakhlallah D, Moldovan L, Agarwal K, Batte K, Shah P, Wisler J, Eubank TD, Tridandapani S, Paulaitis ME, Piper MG, Marsh CB.
Blood. 2013;121(6):984-995.

PMC3567345.

Fcgamma receptor-induced soluble vascular endothelial growth factor receptor-1 (VEGFR-1) production inhibits angiogenesis and enhances efficacy of anti-tumor antibodies.
Justiniano SE, Elavazhagan S, Fatehchand K, Shah P, Mehta P, Roda JM, Mo X, Cheney C, Hertlein E, Eubank TD, Marsh CB, Muthusamy N, Butchar JP, Byrd JC, Tridandapani S.
J Biol Chem. 2013;288(37):26800-26809.

PMC3772225.

Pancreatic cancer-associated stellate cells promote differentiation of myeloid-derived suppressor cells in a STAT3-dependent manner.
Mace TA, Ameen Z, Collins A, Wojcik S, Mair M, Young GS, Fuchs JR, Eubank TD, Frankel WL, Bekaii-Saab T, Bloomston M, Lesinski GB.
Cancer Res. 2013;73(10):3007-3018.

PMC3785672.

Probiotic Lactobacillus reuteri attenuates the stressor-enhanced severity of Citrobacter rodentium infection.
Mackos AR, Eubank TD, Parry NM, Bailey MT.
Infect Immun. 2013;81(9):3253-3263.

PMC3754198.

Intermittent hypoxia exacerbates pancreatic beta-cell dysfunction in a mouse model of diabetes mellitus.
Sherwani SI, Aldana C, Usmani S, Adin C, Kotha S, Khan M, Eubank TD, Scherer PE, Parinandi N, Magalang UJ.
Sleep. 2013;36(12):1849-1858.

PMC3825434.

Prolonged restraint stress increases IL-6, reduces IL-10, and causes persistent depressive-like behavior that is reversed by recombinant IL-10.
Voorhees JL, Tarr AJ, Wohleb ES, Godbout JP, Mo X, Sheridan JF, Eubank TD, Marsh CB.
PLoS One. 2013;8(3):e58488

PMC3592793.

Chronic restraint stress upregulates erythropoiesis through glucocorticoid stimulation.
Voorhees JL, Powell ND, Moldovan L, Mo X, Eubank TD, Marsh CB.
PLoS One. 2013;8(10):e77935

PMC3799740.

The impact of adrenergic signaling in skin cancer progression: possible repurposing of beta-blockers for treatment of skin cancer.
Yang EV, Eubank TD.
Cancer Biomark. 2013;13(3):155-160.


In vivo monitoring of pH, redox status, and glutathione using L-band EPR for assessment of therapeutic effectiveness in solid tumors.
Bobko AA, Eubank TD, Voorhees JL, Efimova OV, Kirilyuk IA, Petryakov S, Trofimiov DG, Marsh CB, Zweier JL, Grigor'ev IA, Samouilov A, Khramtsov VV.
Magn Reson Med. 2012;67(6):1827-1836.

PMC3305854.

Hypoxia inducible factors-mediated inhibition of cancer by GM-CSF: a mathematical model.
Chen D, Roda JM, Marsh CB, Eubank TD, Friedman A.
Bull Math Biol. 2012;74(11):2752-2777.

PMC3936579.

Stabilization of HIF-2alpha induces sVEGFR-1 production from tumor-associated macrophages and decreases tumor growth in a murine melanoma model.
Roda JM, Wang Y, Sumner LA, Phillips GS, Marsh CB, Eubank TD.
J Immunol. 2012;189(6):3168-3177.

PMC3436995.

Modeling the inhibition of breast cancer growth by GM-CSF.
Szomolay B, Eubank TD, Roberts RD, Marsh CB, Friedman A.
J Theor Biol. 2012;303:141-151.


Opposing roles for HIF-1alpha and HIF-2alpha in the regulation of angiogenesis by mononuclear phagocytes.
Eubank TD, Roda JM, Liu H, O'Neil T, Marsh CB.
Blood. 2011;117(1):323-332.

PMC3037754.

HIFs: a-cute answer to inflammation?
Eubank TD, Marsh CB.
Blood. 2011;118(3):485-487.


LyGDI, a novel SHIP-interacting protein, is a negative regulator of FcgammaR-mediated phagocytosis.
Mehta P, Wavreille AS, Justiniano SE, Marsh RL, Yu J, Burry RW, Jarjoura D, Eubank TD, Caligiuri MA, Butchar JP, Tridandapani S.
PLoS One. 2011;6(6):e21175

PMC3114867.

Hypoxia-inducible factor-2alpha regulates GM-CSF-derived soluble vascular endothelial growth factor receptor 1 production from macrophages and inhibits tumor growth and angiogenesis.
Roda JM, Sumner LA, Evans R, Phillips GS, Marsh CB, Eubank TD.
J Immunol. 2011;187(4):1970-1976.

PMC3150377.

Azithromycin decreases crevicular fluid volume and mediator content.
Ho W, Eubank TD, Leblebicioglu B, Marsh CB, Walters J.
J Dent Res. 2010;89(8):831-835.

PMC2908730.

Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death.
Parihar A, Eubank TD, Doseff AI.
J Innate Immun. 2010;2(3):204-215.

PMC2956013.

Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection.
Sliman SM, Eubank TD, Kotha SR, Kuppusamy ML, Sherwani SI, Butler ES, Kuppusamy P, Roy S, Marsh CB, Stern DM, Parinandi NL.
Mol Cell Biochem. 2010;333(1-2):9-26.

PMC3671881.

Trityl-based EPR probe with enhanced sensitivity to oxygen.
Bobko AA, Dhimitruka I, Eubank TD, Marsh CB, Zweier JL, Khramtsov VV.
Free Radic Biol Med. 2009;47(5):654-658.

PMC2739013.

Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages.
Eubank TD, Roberts RD, Khan M, Curry JM, Nuovo GJ, Kuppusamy P, Marsh CB.
Cancer Res. 2009;69(5):2133-2140.

PMC2722508.

Survival of monocytes and macrophages and their role in health and disease.
Hunter MP, Wang Y, Eubank TD, Baran C, Nana-Sinkam P, Marsh CB.
Front Biosci (Landmark Ed). 2009;14:4079-4102.

PMC3708298.

Latency associated peptide has in vitro and in vivo immune effects independent of TGF-beta1.
Ali NA, Gaughan AA, Orosz CG, Baran CP, McMaken S, Wang Y, Eubank TD, Hunter M, Lichtenberger FJ, Flavahan NA, Lawler J, Marsh CB.
PLoS One. 2008;3(4):e1914

PMC2288562.

The role of inflammation in the pathogenesis of idiopathic pulmonary fibrosis.
Bringardner BD, Baran CP, Eubank TD, Marsh CB.
Antioxid Redox Signal. 2008;10(2):287-301.

PMC2737712.

M-CSF signals through the MAPK/ERK pathway via Sp1 to induce VEGF production and induces angiogenesis in vivo.
Curry JM, Eubank TD, Roberts RD, Wang Y, Pore N, Maity A, Marsh CB.
PLoS One. 2008;3(10):e3405

PMC2566603.

Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells.
Parinandi NL, Sharma A, Eubank TD, Kaufman BF, Kutala VK, Marsh CB, Ignarro LJ, Kuppusamy P.
Antioxid Redox Signal. 2007;9(11):1837-1849.


The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival.
Wang Y, Zeigler MM, Lam GK, Hunter MG, Eubank TD, Khramtsov VV, Tridandapani S, Sen CK, Marsh CB.
Am J Respir Cell Mol Biol. 2007;36(1):68-77.

PMC1899309.

Norepinephrine up-regulates the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumor cells.
Yang EV, Sood AK, Chen M, Li Y, Eubank TD, Marsh CB, Jewell S, Flavahan NA, Morrison C, Yeh PE, Lemeshow S, Glaser R.
Cancer Res. 2006;66(21):10357-10364.


GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.
Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB.
Immunity. 2004;21(6):831-842.


M-CSF induces vascular endothelial growth factor production and angiogenic activity from human monocytes.
Eubank TD, Galloway M, Montague CM, Waldman WJ, Marsh CB.
J Immunol. 2003;171(5):2637-2643.


Inhibition of bacterial RNase P by aminoglycoside-arginine conjugates.
Eubank TD, Biswas R, Jovanovic M, Litovchick A, Lapidot A, Gopalan V.
FEBS Lett. 2002;511(1-3):107-112.