Publications of Steven Frisch, PhD

Grainyhead-like 2 reverses the metabolic changes induced by the oncogenic epithelial-mesenchymal transition: effects on anoikis.
Farris JC, Pifer PM, Zheng L, Gottlieb E, Denvir J, Frisch SM.
Mol Cancer Res. 2016;

PMC Journal - In Process.

Grainyhead-like-2 inhibits the coactivator p300, suppressing tubulogenesis and the epithelial-mesenchymal transition.
Pifer PM, Farris JC, Thomas AL, Stoilov P, Denvir J, Smith DM, Frisch SM.
Mol Biol Cell. 2016;

CD44S-hyaluronan interactions protect cells resulting from EMT against anoikis.
Cieply B, Koontz C, Frisch SM.
Matrix Biol. 2015;48(55):65


The wind god promotes lung cancer.
Frisch SM, Schaller MD.
Cancer Cell. 2014;25(5):551-552.

Epithelial-mesenchymal transition and tumor suppression are controlled by a reciprocal feedback loop between ZEB1 and Grainyhead-like-2.
Cieply B, Farris JC, Denvir J, Ford H, Frisch SM.
Cancer Res. 2013;15(73):6299-6309.


Mechanisms that link the oncogenic epithelial-mesenchymal transition to suppression of anoikis.
Frisch SM, Schaller MD, Cieply B.
J.Cell Sci. 2013;126(Pt 1):21-29.


Regulation of anoikis by deleted in breast cancer-1 (DBC1) through NF-kappaB.
Park SH, Riley P, Frisch SM.
Apoptosis. 2013;18(8):949-962.


Suppression of the epithelial-mesenchymal transition by Grainyhead-like-2.
Cieply B, Riley P, Pifer PM, Widmeyer J, Addison JB, Ivanov AV, Denvir J, Frisch SM.
Cancer Res. 2012;72(9):2440-2453.


A pathway for the control of anoikis sensitivity by E-cadherin and epithelial-to-mesenchymal transition.
Kumar S, Park SH, Cieply B, Schupp J, Killiam E, Zhang F, Rimm DL, Frisch SM.
Mol Cell Biol. 2011;31(19):4036-4051.


PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments.
Schaller MD, Frisch SM.
Cancer Biol Ther. 2010;9(10):791-793.

Caspase-8: fly or die.
Frisch SM.
Cancer Res. 2008;68(12):4491-4493.

Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb.
Huang X, Masselli A, Frisch SM, Hunton IC, Jiang Y, Wang JY.
J Biol Chem. 2007;282(40):29401-29413.

Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility.
Senft J, Helfer B, Frisch SM.
Cancer Res. 2007;67(24):11505-11509.