Publications of Pius Joseph

Authors' response to the letter to the editor: "Definition of sleep duration and carotid artery intima media thickness: caution for risk assessment".
Ma CC, Burchfiel CM, Charles LE, Dorn JM, Andrew ME, Gu JK, Joseph PN, Fekedulegn D, Slaven JE, Hartley TA, Mnatsakanova A, Violanti JM.
Am J Ind Med. 2014;57(4):490-491.


Central adiposity and subclinical cardiovascular disease in police officers.
Baughman P, Fekedulegn D, Andrew ME, Joseph PN, Dorn JM, Violanti JM, Burchfiel CM.
ISRN.Obes. 2013;2013:895687

PMC3901981.

Blood transcriptomics: applications in toxicology.
Joseph PN, Umbright C, Sellamuthu R.
J Appl Toxicol. 2013;33:1193-1202.


Associations of objectively measured and self-reported sleep duration with carotid artery intima media thickness among police officers.
Ma CC, Burchfiel CM, Charles LE, Dorn JM, Andrew ME, Gu JK, Joseph PN, Fekedulegn D, Slaven JE, Hartley TA, Mnatsakanova A, Violanti JM.
Am J Ind Med. 2013;56(11):1341-1351.


Molecular insights into the progression of crystalline silica-induced pulmonary toxicity in rats.
Sellamuthu R, Umbright C, Roberts JR, Cumpston AD, McKinney W, Chen BT, Frazer D, Li S, Kashon ML, Joseph PN.
J Appl Toxicol. 2013;33(4):301-312.


Associations of Depressive Symptoms and Brachial Artery Reactivity among Police Officers.
Violanti JM, Charles LE, Gu JK, Burchfiel CM, Andrew ME, Joseph PN, Dorn JM.
Saf Health Work. 2013;4(1):27-36.

PMC3601294.

Transcriptomics analysis of lungs and peripheral blood of crystalline silica-exposed rats.
Sellamuthu R, Umbright C, Roberts JR, Chapman R, Young SH, Richardson D, Cumpston J, McKinney W, Chen BT, Frazer D, Li S, Kashon ML, Joseph PN.
Inhal Toxicol. 2012;24(9):570-579.


C-reactive protein, Interleukin-6, and posttraumatic stress disorder symptomology in urban police officers.
McCanlies EC, Araia SK, Joseph PN, Mnatsakanova A, Andrew ME, Burchfiel CM, Violanti JM.
Cytokine. 2011;55(1):74-78.


Blood gene expression profiling detects silica exposure and toxicity.
Sellamuthu R, Umbright C, Roberts JR, Chapman R, Young SH, Richardson D, Leonard H, McKinney W, Chen B, Frazer D, Li S, Kashon ML, Joseph PN.
Toxicol Sci. 2011;122(2):253-264.


Mechanisms of crystalline silica-induced pulmonary toxicity revealed by global gene expression profiling.
Sellamuthu R, Umbright C, Li S, Kashon ML, Joseph PN.
Inhal Toxicol. 2011;23(14):927-937.


Irritancy and allergic responses induced by topical application of ortho-phthalaldehyde.
Anderson SE, Umbright C, Sellamuthu R, Fluharty K, Kashon ML, Franko J, Jackson LG, Johnson VJ, Joseph PN.
Toxicol Sci. 2010;115(2):435-443.

PMC2871752.

Antioxidants and pulmonary function among police officers.
Charles LE, Burchfiel CM, Mnatsakanova A, Fekedulegn D, Tinney-Zara C, Joseph PN, Schunemann HJ, Violanti JM, Andrew ME, Ochs-Balcom HM.
J Occup Environ Med. 2010;52(11):1124-1131.


Endothelial function, a biomarker of subclinical cardiovascular disease, in urban police officers.
Joseph PN, Violanti JM, Donahue R, Andrew ME, Trevisan M, Burchfiel CM, Dorn J.
J Occup Environ Med. 2010;52(10):1004-1008.


Blood gene expression markers to detect and distinguish target organ toxicity.
Umbright C, Sellamuthu R, Li SQ, Kashon ML, Luster MI, Joseph PN.
Mol Cell Biochem. 2010;335(1-2):223-234.


Police work and subclinical atherosclerosis.
Joseph PN, Violanti JM, Donahue R, Andrew ME, Trevisan M, Burchfiel CM, Dorn J.
J Occup Environ Med. 2009;51(6):700-707.


Mechanisms of cadmium carcinogenesis.
Joseph PN.
Toxicol Appl Pharmacol. 2009;238(3):272-279.


Cardiovascular reactivity to psychological stress and carotid intima-media thickness in children.
Roemmich JN, Lobarinas CL, Joseph PN, Lambiase MJ, Archer FD, Dorn J.
Psychophysiology. 2009;46(2):293-299.


Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts.
Joseph PN, He Q, Umbright C.
Toxicol Sci. 2008;103(2):325-334.


Subclinical markers of cardiovascular disease in urban police officers and a general population sample.
Joseph PN, Violanti JM, Donahue R, Andrew ME, Burchfiel CM, Dorn J.
Am J Epidemiol. 2008;167(11):S65-S65.


Estimation of the maximum flow-mediated brachial artery response using local regression methods.
Andrew ME, Li S, Fekedulegn D, Dorn J, Joseph PN, Violanti JM, Burchfiel CM.
Physiol Meas. 2007;28(10):1213-1224.


The Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) pilot study: methods and participant characteristics.
Violanti JM, Burchfiel CM, Miller DB, Andrew ME, Dorn J, Wactawski-Wende J, Beighley CM, Pierino K, Joseph PN, Vena JE, Sharp DS, Trevisan M.
Ann Epidemiol. 2006;16(2):148-156.


Sodium arsenite-induced inhibition of eukaryotic translation initiation factor 4E (eIF4E) results in cytotoxicity and cell death.
Othumpangat S, Kashon ML, Joseph PN.
Mol Cell Biochem. 2005;279(1-2):123-131.


Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride.
Othumpangat S, Kashon ML, Joseph PN.
J Biol Chem. 2005;280(26):25162-25169.


Expression profile of eukaryotic translation factors in human cancer tissues and cell lines.
Joseph PN, O'Kernick CM, Othumpangat S, Lei YX, Yuan BZ, Ong TM.
Mol Carcinog. 2004;40(3):171-179.


Oncogenic potential of mouse translation elongation factor-1 delta, a novel cadmium-responsive proto-oncogene.
Joseph PN, Lei YX, Whong WZ, Ong TM.
J Biol Chem. 2002;277(8):6131-6136.


Antisense inhibition of translation initiation factor 3 reverses its oncogenic potential.
Lei YX, Joseph PN, Ong TM.
Teratog Carcinog Mutagen. 2002;22(6):403-409.


Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun, and c-myc proto-oncogenes: role of cellular calcium and reactive oxygen species.
Joseph PN, Muchnok TK, Klishis ML, Roberts JR, Antonini JM, Whong WZ, Ong TM.
Toxicol Sci. 2001;61(2):295-303.


Gene expression profile in BALB/c-3T3 cells transformed with beryllium sulfate.
Joseph PN, Muchnok TK, Ong TM.
Mol Carcinog. 2001;32(1):28-35.


NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones.
Joseph PN, Jaiswal AK.
Br J Cancer. 1998;77(5):709-719.

PMC2149967.

Hydroquinones cause specific mutations and lead to cellular transformation and in vivo tumorigenesis.
Joseph PN, Klein-Szanto AJP, Jaiswal AK.
Br J Cancer. 1998;78(3):312-320.

PMC2063037.

Non-enzymatic and enzymatic activation of mitomycin C: identification of a unique cytosolic activity.
Joseph PN, Xu Y, Jaiswal AK.
Int J Cancer. 1996;65(2):263-271.


Inhibition of NAD(P)H:quinone oxidoreductase1 in ethacrynic acid-resistant human colon carcinoma cells.
Joseph PN, Sharma MC, Jaiswal AK.
Biochem Pharmacol. 1994;47(11):2011-2015.


NAD(P)H:quinone oxidoreductase1 (DT diaphorase) specifically prevents the formation of benzo[a]pyrene quinone-DNA adducts generated by cytochrome P4501A1 and P450 reductase.
Joseph PN, Jaiswal AK.
Proc Natl Acad Sci USA. 1994;91(18):8413-8417.

PMC44616.

NAD(P)H:quinone oxidoreductase1 (DT-diaphorase): expression, regulation, and role in cancer.
Joseph PN, Xie T, Xu Y, Jaiswal AK.
Oncol Res. 1994;6(10-11):525-532.


The role of specific reductases in the intracellular activation and binding of 2-nitroimidazoles.
Joseph PN, Jaiswal AK, Stobbe CC, Chapman JD.
Int J Radiat Oncol Biol Phys. 1994;29(2):351-355.


Placental peroxidase--further purification of the enzyme and oxidation of thiobenzamide.
Joseph PN, Srinivasan NS, Kulkarni AP.
Placenta. 1993;14(3):309-319.


Purification and partial characterization of lipoxygenase with dual catalytic activities from human term placenta.
Joseph PN, Srinivasan SN, Kulkarni AP.
Biochem J. 1993;293 ( Pt 1):83-91.

PMC1134323.

Peroxidase: a novel pathway for chemical oxidation in human term placenta.
Joseph PN, Murthy KR, Nelson JL, Kulkarni AP.
Placenta. 1992;13(6):545-554.


Effect of vitamin A on hexachlorocyclohexane (HCH) toxicity in the rat.
Joseph PN, Shivanandappa T, Narasimhamurthy K, Krishnakumari MK.
Gen Pharmacol. 1992;23(6):1159-1164.


Role of vitamin A in the haematotoxicity of hexachlorocyclohexane (HCH) in the rat.
Joseph PN, Viswanatha S, Krishnakumari MK.
J Environ Sci Health B. 1992;27(3):269-280.


Inhibition of human term placental and fetal liver glutathione-S-transferases by fatty acids and fatty acid esters.
Mitra A, Govindwar S, Joseph PN, Kulkarni A.
Toxicol Lett. 1992;60(3):281-288.