Publications of Jun Liu, PhD

Inhibition of autophagy potentiated the antitumor effect of nedaplatin in cisplatin-resistant nasopharyngeal carcinoma cells.
Liu Z, Liu J, Li L, Nie D, Tao Q, Wu J, Fan J, Lin C, Zhao S, Ju D.
PLoS One. 2015;10(8):e0135236


Helicobacter pylori FKBP-type PPIase promotes gastric epithelial cell proliferation and anchorage-independent growth through activation of ERK-mediated mitogenic signaling pathway.
Zhu Y, Chen M, Gong Y, Liu Z, Li A, Kang D, Han F, Liu J, Liu J, Yuan Y.
FEMS Microbiol Lett. 2015;362(7)

Differential proteomic analysis of caveolin-1 KO cells reveals Sh2b3 and Clec12b as novel interaction partners of caveolin-1 and Capns1 as a potential mediator of caveolin-1-induced apoptosis.
Kulkarni YM, Liu C, Qi Q, Zhu Y, Klinke DJ, Liu J.
Analyst. 2013;138(22):6986-6996.


Cryoelectron tomography reveals the sequential assembly of bacterial flagella in Borrelia burgdorferi.
Zhao XW, Zhang K, Boquoi T, Hu B, Motaleb MA, Miller KA, James ME, Charon NW, Manson MD, Norris SJ, Li CH, Liu J.
Proc Natl Acad Sci USA. 2013;110(35):14390-14395.


The unique paradigm of spirochete motility and chemotaxis.
Charon NW, Cockburn A, Li C, Liu J, Miller KA, Miller MR, Motaleb MA, Wolgemuth CW.
Annu Rev Microbiol. 2012;66:349-370.


A database de-identification framework to enable direct queries on medical data for secondary use.
Erdal BS, Liu J, Ding J, Chen J, Marsh CB, Kamal J, Clymer BD.
Methods Inf Med. 2012;51(3):229-241.

Two CheW coupling proteins are essential in a chemosensory pathway of Borrelia burgdorferi.
Zhang K, Liu J, Tu Y, Xu H, Charon NW, Li C.
Mol Microbiol. 2012;85(4):782-794.


miR-190-Mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis.
Beezhold KJ, Liu J, Kan H, Meighan T, Castranova V, Shi X, Chen F.
Toxicol Sci. 2011;123(2):411-420.


Subtractive hybridization analysis of gastric diseases-associated Helicobacter pylori identifies peptidyl-prolyl isomerase as a potential marker for gastric cancer.
Gong YH, Chen M, Xu Y, Dong N, Sang Z, Liu J, Yuan Y.
FEMS Microbiol Lett. 2011;320(2):103-109.

Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage.
Mistry PK, Liu J, Yang M, Nottoli T, McGrath J, Jain D, Zhang K, Keutzer J, Chuang WL, Mehal WZ, Zhao H, Lin A, Mane S, Liu X, Peng YZ, Li JH, Agrawal M, Zhu LL, Blair HC, Robinson LJ, Iqbal J, Sun L, Zaidi M.
Proc Natl Acad Sci U S A. 2010;107(45):19473-19478.


Toward a fully de-identified biomedical information warehouse.
Liu J, Erdal S, Silvey SA, Ding J, Riedel JD, Marsh CB, Kamal J.
AMIA Annu Symp Proc. 2009;2009:370-374.


A conserved sequence in caveolin-1 is both necessary and sufficient for caveolin polarity and cell directional migration.
Sun XH, Liu ZY, Chen H, Beardsley AR, Qi Q, Liu J.
FEBS Lett. 2009;583(22):3681-3689.

Caveolin-1 up-regulation during epithelial to mesenchymal transition is mediated by focal adhesion kinase.
Bailey KM, Liu J.
J Biol Chem. 2008;283(20):13714-13724.


Bayesian mass spectra peak alignment from mass charge ratios.
Liu J, Yu W, Wu B, Zhao H.
Cancer Inform. 2008;6:217-241.


Overexpression of caveolin-1 inhibits endothelial cell proliferation by arresting the cell cycle at G0/G1 phase.
Fang K, Fu W, Beardsley AR, Sun X, Lisanti MP, Liu J.
Cell Cycle. 2007;6(2):199-204.

Identification of a novel domain at the N terminus of caveolin-1 that controls rear polarization of the protein and caveolae formation.
Sun XH, Flynn DC, Castranova V, Millecchia LL, Beardsley AR, Liu J.
J Biol Chem. 2007;282(10):7232-7241.

Loss of caveolin-1 polarity impedes endothelial cell polarization and directional movement.
Beardsley AR, Fang K, Mertz H, Castranova V, Friend S, Liu J.
J Biol Chem. 2005;280(5):3541-3547.

The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism.
Liu J, Ericksen SS, Sivaneri M, Besspiata D, Fisher CW, Szklarz GD.
Arch Biochem Biophys. 2004;424(1):33-43.

Transient mechanoactivation of neutral sphingomyelinase in caveolae to generate ceramide.
Czarny M, Liu J, Oh P, Schnitzer JE.
J Biol Chem. 2003;278(7):4424-4430.

Characterization of substrate binding to cytochrome P450 1A1 using molecular modeling and kinetic analyses: case of residue 382.
Liu J, Ericksen SS, Besspiata D, Fisher CW, Szklarz GD.
Drub Metab Dispos. 2003;31(4):412-420.

Caveolin-1 expression enhances endothelial capillary tubule formation.
Liu J, Wang XB, Park DS, Lisanti MP.
J Biol Chem. 2002;277(12):10661-10668.

Caveolin-1 expression negatively regulates cell cycle progression by inducing G(0)/G(1) arrest via a p53/p21(WAF1/Cip1)-dependent mechanism.
Galbiati F, Volonte D, Liu J, Capozza F, Frank PG, Zhu L, Pestell RG, Lisanti MP.
Mol Biol Cell. 2001;12(8):2229-2244.


Caveolin-1 expression sensitizes fibroblastic and epithelial cells to apoptotic stimulation.
Liu J, Lee P, Galbiati F, Kitsis RN, Lisanti MP.
Am J Physiol Cell Physiol. 2001;280(4):C823-C835.

Caveolin-1, a putative tumour suppressor gene.
Razani B, Schlegel A, Liu J, Lisanti MP.
Biochem Soc Trans. 2001;29(Pt 4):494-499.

Angiogenesis activators and inhibitors differentially regulate caveolin-1 expression and caveolae formation in vascular endothelial cells. Angiogenesis inhibitors block vascular endothelial growth factor-induced down-regulation of caveolin-1.
Liu J, Razani B, Tang S, Terman BI, Ware JA, Lisanti MP.
J Biol Chem. 1999;274(22):15781-15785.

Organized endothelial cell surface signal transduction in caveolae distinct from glycosylphosphatidylinositol-anchored protein microdomains.
Liu J, Oh P, Horner T, Rogers RA, Schnitzer JE.
J Biol Chem. 1997;272(11):7211-7222.

Endothelial caveolae have the molecular transport machinery for vesicle budding, docking, and fusion including VAMP, NSF, SNAP, annexins, and GTPases.
Schnitzer JE, Liu J, Oh P.
J Biol Chem. 1995;270(24):14399-14404.

Separation of caveolae from associated microdomains of GPI-anchored proteins.
Schnitzer JE, McIntosh DP, Dvorak AM, Liu J, Oh P.
Science. 1995;269(5229):1435-1439.

Bacterial lipopolysaccharide has structural similarity to ceramide and stimulates ceramide-activated protein kinase in myeloid cells.
Joseph CK, Wright SD, Bornmann WG, Randolph JT, Kumar ER, Bittman R, Liu J, Kolesnick RN.
J Biol Chem. 1994;269(26):17606-17610.

Renaturation and tumor necrosis factor-alpha stimulation of a 97-kDa ceramide-activated protein kinase.
Liu J, Mathias S, Yang Z, Kolesnick RN.
J Biol Chem. 1994;269(4):3047-3052.

Enhancement of noradrenaline-induced inositol polyphosphate formation by glucocorticoids in rat vascular smooth muscle cells.
Liu J, Haigh RM, Jones CT.
J Endocrinol. 1992;133(3):405-411.