Publications of Ming Pei, MD, PhD

SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma.
Luanpitpong S, Li J, Manke A, Brundage KM, Ellis E, McLaughlin SL, Angsutararux P, Chanthra N, Voronkova M, Chen YC, Wang L, Chanvorachote P, Pei M, Issaragrisil S, Rojanasakul Y.
Oncogene. 2015; [Epub ahead of print]

PMC Journal - In Process.

A comparison of tissue engineering based repair of calvarial defects using adipose stem cells from normal and osteoporotic rats.
Pei M, Li J, McConda DB, Wen S, Clovis NB, Danley SS.
Bone. 2015;78:1-10.

PMC4466199.

Impact of tissue-specific stem cells on lineage-specific differentiation: a focus on the musculoskeletal system.
Pizzute T, Lynch K, Pei M.
Stem Cell Rev. 2015;11(1):119-132.

PMC4326629.

Evolving concepts of chondrogenic differentiation: history, state-of-the-art and future perspectives.
Tang X, Fan L, Pei M, Zeng L, Ge Z.
Eur Cell Mater. 2015;30:12-27.


sb203580 preconditioning recharges matrix-expanded human adult stem cells for chondrogenesis in an inflammatory environment - A feasible approach for autologous stem cell based osteoarthritic cartilage repair.
Zhang Y, Pizzute T, Li J, He F, Pei M.
Biomaterials. 2015;64:88-97.

PMC4503335.

Delineation of in vitro chondrogenesis of human synovial stem cells following preconditioning using decellularized matrix.
Zhang Y, Li J, Davis ME, Pei M.
Acta Biomater. 2015;20:39-50.

PMC4428941.

Melatonin reverses H2 O2 -induced premature senescence in mesenchymal stem cells via the SIRT1-dependent pathway.
Zhou L, Chen X, Liu T, Gong Y, Chen S, Pan G, Cui W, Luo ZP, Pei M, Yang H, He F.
J Pineal Res. 2015;59(2):190-205.

PMC4523475.

Quantitative susceptibility mapping of multiple sclerosis lesions at various ages.
Chen W, Gauthier SA, Gupta A, Comunale J, Liu T, Wang S, Pei M, Pitt D, Wang Y.
Radiology. 2014;271(1):183-192.


Preparation, characterization and application of magnetic Fe3O4-CS for the adsorption of orange I from aqueous solutions.
Du Y, Pei M, He Y, Yu F, Guo W, Wang L.
PLoS One. 2014;9(10):e108647

PMC4182735.

Extracellular matrix modulates the biological effects of melatonin in mesenchymal stem cells.
He F, Liu X, Xiong K, Chen S, Zhou L, Cui W, Pan G, Luo ZP, Pei M, Gong Y.
J Endocrinol. 2014;223(2):167-180.


MicroRNA-155 broadly orchestrates inflammation-induced changes of microRNA expression in breast cancer.
Hu S, Zhu W, Zhang LF, Pei M, Liu MF.
Cell Res. 2014;24(2):254-257.

PMC3915901.

Matrilin-3 chondrodysplasia mutations cause attenuated chondrogenesis, premature hypertrophy and aberrant response to TGF-beta in chondroprogenitor cells.
Jayasuriya CT, Zhou FH, Pei M, Wang Z, Lemme NJ, Haines P, Chen Q.
Int J Mol Sci. 2014;15(8):14555-14573.

PMC4159868.

Rejuvenation of chondrogenic potential in a young stem cell microenvironment.
Li J, Hansen KC, Zhang Y, Dong C, Dinu CZ, Dzieciatkowska M, Pei M.
Biomaterials. 2014;35(2):642-653.


Can arthroscopically harvested synovial stem cells be preferentially sorted using stage-specific embryonic antigen 4 antibody for cartilage, bone, and adipose regeneration?
Li J, Campbell DD, Bal GK, Pei M.
Arthroscopy. 2014;30(3):352-361.


Significance of epigenetic landscape in cartilage regeneration from the cartilage development and pathology perspective.
Li JT, Ohliger J, Pei M.
Stem Cells Dev. 2014;23(11):1178-1194.

PMC4027988.

Expansion on a matrix deposited by nonchondrogenic urine stem cells strengthens the chondrogenic capacity of repeated-passage bone marrow stromal cells.
Pei M, Li JT, Zhang Y, Liu GH, Wei L, Zhang YY.
Cell Tissue Res. 2014;356(2):391-403.

PMC4128485.

Advances in mesenchymal stem cell-based strategies for cartilage repair and regeneration.
Toh WS, Foldager CB, Pei M, Hui JH.
Stem Cell Rev. 2014;10(5):686-696.


Demineralized bone matrix combined bone marrow mesenchymal stem cells, Bone Morphogenetic protein-2 and Transforming Growth Factor-beta3 gene promoted pig cartilage defect repair.
Wang X, Li Y, Han R, He C, Wang G, Wang J, Zheng J, Pei M, Wei L.
PLoS One. 2014;9(12):e116061

PMC4278773.

Anti-Inflammatory strategies in cartilage repair.
Zhang Y, Pizzute T, Pei M.
Tissue Eng Part B Rev. 2014;29(6):655-668.

PMC4241874.

A review of crosstalk between MAPK and Wnt signals and its impact on cartilage regeneration.
Zhang Y, Pizzute T, Pei M.
Cell Tissue Res. 2014;358(3):633-649.

PMC4234693.

Extracellular matrix enhances differentiation of adipose stem cells from infrapatellar fat pad toward chondrogenesis.
He F, Pei M.
J Tissue Eng Regen Med. 2013;7(1):73-84.


Repair of large animal partial-thickness cartilage defects through intraarticular injection of matrix-rejuvenated synovium-derived stem cells.
Pei M, He F, Li J, Tidwell JE, Jones AC, McDonough EB.
Tissue Eng Part A. 2013;19(9-10):1144-1154.


Antioxidation of decellularized stem cell matrix promotes human synovium-derived stem cell-based chondrogenesis.
Pei M, Zhang Y, Li J, Chen D.
Stem Cells Dev. 2013;22(6):889-900.

PMC3585742.

Reconstruction of an in vitro niche for the transition from intervertebral disc development to nucleus pulposus regeneration.
Shoukry M, Li J, Pei M.
Stem Cells Dev. 2013;22(8):1162-1176.

PMC3613965.

Subcellular relocation of histone deacetylase 4 regulates growth plate chondrocyte differentiation through Ca2+/calmodulin-dependent kinase IV.
Guan Y, Chen Q, Yang X, Haines P, Pei M, Terek R, Wei X, Zhao T, Wei L.
Am J Physiol Cell Physiol. 2012;303(1):C33-C40.

PMC3404523.

Rejuvenation of nucleus pulposus cells using extracellular matrix deposited by synovium-derived stem cells.
He F, Pei M.
Spine (Phila Pa 1976.). 2012;37(6):459-469.


Synovium-derived stem cells: a tissue-specific stem cell for cartilage engineering and regeneration.
Jones BA, Pei M.
Tissue Eng Part B Rev. 2012;18(4):301-311.


Cell senescence: a challenge in cartilage engineering and regeneration.
Li JT, Pei M.
Tissue Eng Part B Rev. 2012;


Modulation of In Vitro microenvironment facilitates synovium-derived stem cell-based nucleus pulposus tissue regeneration.
Pei M, Shoukry M, Li J, Daffner SD, France JC, Emery SE.
Spine (Phila Pa 1976.). 2012;


Extracellular matrix deposited by synovium-derived stem cells delays replicative senescent chondrocyte dedifferentiation and enhances redifferentiation.
Pei M, He F.
J Cell Physiol. 2012;227(5):2163-2174.

PMC3265606.

Activation of Indian hedgehog promotes chondrocyte hypertrophy and upregulation of MMP-13 in human osteoarthritic cartilage.
Wei F, Zhou J, Wei X, Zhang J, Fleming BC, Terek R, Pei M, Chen Q, Liu T, Wei L.
Osteoarthritis Cartilage. 2012;20(7):755-763.

PMC3374008.

Creation of an in vitro microenvironment to enhance human fetal synovium-derived stem cell chondrogenesis.
Li J, He F, Pei M.
Cell Tissue Res. 2011;345(3):357-365.


Optimization of an in vitro three-dimensional microenvironment to reprogram synovium-derived stem cells for cartilage tissue engineering.
Li J, Pei M.
Tissue Eng Part A. 2011;17(5-6):703-712.


Three dimensional cell expansion substrate for cartilage tissue engineering and regeneration: a comparision in decellularized matrix deposited by synovium-derived stem cells and chondrocytes.
Pei M, He F, Wei L.
J Tissue Sci Eng. 2011;2(2):1000104


A review of decellularized stem cell matrix: a novel cell expansion system for cartilage tissue engineering.
Pei M, Li JT, Shoukry M, Zhang Y.
Eur Cell Mater. 2011;22:333-343.


Expansion on extracellular matrix deposited by human bone marrow stromal cells facilitates stem cell proliferation and tissue-specific lineage potential.
Pei M, He F, Kish VL.
Tissue Eng Part A. 2011;17(23-24):3067-3076.

PMC3226057.

Failure of xenoimplantation using porcine synovium-derived stem cell-based cartilage tissue constructs for the repair of rabbit osteochondral defects.
Pei M, Yan Z, Shoukry M, Boyce BM.
J Orthop Res. 2010;28(8):1064-1070.


Meniscus reconstruction through coculturing meniscus cells with synovium-derived stem cells on small intestine submucosa--a pilot study to engineer meniscus tissue constructs.
Tan Y, Zhang Y, Pei M.
Tissue Eng Part A. 2010;16(1):67-79.


Stimulation of chondrocyte hypertrophy by chemokine stromal cell-derived factor 1 in the chondro-osseous junction during endochondral bone formation.
Wei L, Kanbe K, Lee M, Wei X, Pei M, Sun X, Terek R, Chen Q.
Dev Biol. 2010;341(1):236-245.

PMC2862458.

CD14-negative isolation enhances chondrogenesis in synovial fibroblasts.
Bilgen B, Ren Y, Pei M, Aaron RK, Ciombor DM.
Tissue Eng Part A. 2009;15(11):3261-3270.

PMC2792095.

Coculture of synovium-derived stem cells and nucleus pulposus cells in serum-free defined medium with supplementation of transforming growth factor-beta1: a potential application of tissue-specific stem cells in disc regeneration.
Chen S, Emery SE, Pei M.
Spine (Phila Pa 1976.). 2009;34(12):1272-1280.


Reconstruction of an in vitro tissue-specific microenvironment to rejuvenate synovium-derived stem cells for cartilage tissue engineering.
He F, Chen X, Pei M.
Tissue Eng Part A. 2009;15(12):3809-3821.


Repair of full-thickness femoral condyle cartilage defects using allogeneic synovial cell-engineered tissue constructs.
Pei M, He F, Boyce BM, Kish VL.
Osteoarthritis Cartilage. 2009;17(6):714-722.


Melatonin enhances cartilage matrix synthesis by porcine articular chondrocytes.
Pei M, He F, Wei L, Rawson A.
J Pineal Res. 2009;46(2):181-187.


Histone deacetylase 4 promotes TGF-beta1-induced synovium-derived stem cell chondrogenesis but inhibits chondrogenically differentiated stem cell hypertrophy.
Pei M, Chen D, Li J, Wei L.
Differentiation. 2009;78(5):260-268.


Synovium-derived stem cell-based chondrogenesis.
Pei M, He F, Vunjak-Novakovic G.
Differentiation. 2008;76(10):1044-1056.

PMC2772098.

Engineering of functional cartilage tissue using stem cells from synovial lining: a preliminary study.
Pei M, He F, Kish VL, Vunjak-Novakovic G.
Clin Orthop Relat Res. 2008;466(8):1880-1889.

PMC2584267.

Enhancing and maintaining chondrogenesis of synovial fibroblasts by cartilage extracellular matrix protein matrilins.
Pei M, Luo J, Chen Q.
Osteoarthritis Cartilage. 2008;16(9):1110-1117.

PMC2596998.

Morphology controllable nanostructured chitosan matrix and its cytocompatibility.
Qi L, Pal S, Dutta P, Seehra M, Pei M.
J Biomed Mater Res A. 2008;87(1):236-244.


Mechanical properties and remodeling of hybrid cardiac constructs made from heart cells, fibrin, and biodegradable, elastomeric knitted fabric.
Boublik J, Park H, Radisic M, Tognana E, Chen F, Pei M, Vunjak-Novakovic G, Freed LE.
Tissue Eng. 2005;11(7-8):1122-1132.


Long-term culture of tissue engineered cartilage in a perfused chamber with mechanical stimulation.
Seidel JO, Pei M, Gray ML, Langer R, Freed LE, Vunjak-Novakovic G.
Biorheology. 2004;41(3-4):445-458.


Bioreactors mediate the effectiveness of tissue engineering scaffolds.
Pei M, Solchaga LA, Seidel J, Zeng L, Vunjak-Novakovic G, Caplan AI, Freed LE.
FASEB J. 2002;16(12):1691-1694.


Growth factors for sequential cellular de- and re-differentiation in tissue engineering.
Pei M, Seidel J, Vunjak-Novakovic G, Freed LE.
Biochem Biophys Res Commun. 2002;294(1):149-154.


Expression of collagen type I, II and III in loose body of osteoarthritis.
Pei M, Yu CL, Qu MY.
J Orthop Sci. 2000;5(3):288-293.