Publications

Suppression of arthritis-induced bone erosion by a CRAC channel antagonist.
Blair HC, Soboloff J, Robinson LJ, Tourkova IL, Larrouture QC, Witt MR, Holaskova I, Schafer R, Elliott M, Hirsch R, Barnett JB.
RMD Open. 2016;2(1):e000093

PMC4716559.

Combinatorial approaches to evaluate nanodiamond uptake and induced cellular fate.
Eldawud R, Reitzig M, Opitz J, Rojansakul Y, Jiang W, Nangia S, Dinu CZ.
Nanotechnology. 2016;27(8):085107


Gallic acid, a phenolic compound, exerts anti-angiogenic effects via the PTEN/AKT/HIF-1alpha/VEGF signaling pathway in ovarian cancer cells.
He Z, Chen AY, Rojanasakul Y, Rankin GO, Chen YC.
Oncol Rep. 2016;35(1):291-297.


Autophagy-induced apoptosis in lung cancer cells by a novel digitoxin analog.
Kulkarni YM, Kaushik V, Azad N, Wright C, Rojanasakul Y, O'Doherty G, Iyer AK.
J Cell Physiol. 2016;231(4):817-828.

PMC4751068.

Relationships of climate and irrigation factors with malaria parasite incidences in two climatically dissimilar regions in India.
Lee E, Burkhart J, Olson S, Billings AA, Patz JA, Harner EJ.
Journal of Arid Environments. 2016;124:214-224.


Depleting Tumor-NQO1 Potentiates Anoikis and Inhibits Growth of NSCLC.
Madajewski B, Boatman MA, Chakrabarti G, Boothman DA, Bey EA.
Mol Cancer Res. 2016;14(1):14-25.

PMC4715967.

Effects of laser printer-emitted engineered nanoparticles on cytotoxicity, chemokine expression, reactive oxygen species, DNA methylation, and DNA damage: a comprehensive in vitro analysis in human small airway epithelial cells, macrophages, and lymphoblasts.
Pirela SV, Miousse IR, Lu X, Castranova V, Thomas T, Qian Y, Bello D, Kobzik L, Koturbash I, Demokritou P.
Environ Health Perspect. 2016;124(2):210-219.

PMC4749083.

Effects of nickel-oxide nanoparticle pre-exposure dispersion status on bioactivity in the mouse lung.
Sager T, Wolfarth M, Keane M, Porter D, Castranova V, Holian A.
Nanotoxicology. 2016;10(2):151-161.


Toxicological assessment of CoO and La2O3 metal oxide nanoparticles in human small airway epithelial cells.
Sisler JD, Pirela SV, Shaffer J, Mihalchik AL, Chisholm WP, Andrew ME, Schwegler-Berry D, Castranova V, Demokritou P, Qian Y.
Toxicol Sci. 2016; [Epub ahead of print]


mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo-alveolar adenoma and adenocarcinoma after multi-walled carbon nanotube inhalation exposure in mice.
Snyder-Talkington BN, Dong C, Sargent LM, Porter DW, Staska LM, Hubbs AF, Raese R, McKinney W, Chen BT, Battelli L, Lowry DT, Reynolds SH, Castranova V, Qian Y, Guo NL.
J Appl Toxicol. 2016;36(1):161-174.

PMC4418205.

The influence of inhaled multi-walled carbon nanotubes on the autonomic nervous system.
Zheng W, McKinney W, Kashon M, Salmen R, Castranova V, Kan H.
Part Fibre Toxicol. 2016;13(1):8

PMC4750189.

Dipping into a drink: Basil-seed supported silver nanoparticles as surface-enhanced Raman scattering substrates for toxic molecule detection.
Zhou QT, Meng GW, Wu NQ, Zhou NN, Chen BS, Li FD, Huang Q.
Sensors and Actuators B-Chemical. 2016;223:447-452.


Development and validation of a smoking expectancies measure for adolescents seeking to quit smoking.
Branstetter SA, Mercincavage M, Dino GA, Horn KA.
Subst Abus. 2015;36(1):119-126.

PMC4562463.

Gene expression profile of human lung epithelial cells chronically exposed to single-walled carbon nanotubes.
Chen DQ, Stueckle T, Luanpitpong S, Rojanasakul Y, Lu YJ, Wang LY.
Nano Res Lett. 2015;10:1-12.

PMC4314466.

The flavonoid nobiletin inhibits tumor growth and angiogenesis of ovarian cancers via the Akt pathway.
Chen J, Chen AY, Huang H, Ye X, Rollyson WD, Perry HE, Brown KC, Rojanasakul Y, Rankin GO, Dasgupta P, Chen YC.
Int J Oncol. 2015;46(6):2629-2638.

PMC4441297.

Controlling plasmon-induced resonance energy transfer and hot electron injection processes in metal@TiO2 core-shell nanoparticles.
Cushing SK, Li JT, Bright J, Yost BT, Zheng P, Bristow AD, Wu NQ.
Journal of Physical Chemistry C. 2015;119(28):16239-16244.


Theoretical maximum efficiency of solar energy conversion in plasmonic metal-semiconductor heterojunctions.
Cushing SK, Bristow AD, Wu NQ.
Phys Chem Chem Phys. 2015;17(44):30013-30022.


Carbon nanotube uptake changes the biomechanical properties of human lung epithelial cells in a time-dependent manner.
Dong CB, Eldawud R, Sargent LM, Kashon ML, Lowry D, Rojanasakul Y, Dinu CZ.
J Mater Chem B Mater Biol Med. 2015;3:3983-3992.

PMC4486612.

mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung inflammatory and fibrotic pathologies in mice.
Dymacek J, Snyder-Talkington BN, Porter DW, Mercer RR, Wolfarth MG, Castranova V, Qian Y, Guo NL.
Toxicol Sci. 2015;144(1):51-64.

PMC4349139.

Electronic platform for real-time multi-parametric analysis of cellular behavior post-exposure to single-walled carbon nanotubes.
Eldawud R, Wagner A, Dong C, Rojanasakul Y, Zoica DC.
Biosens Bioelectron. 2015;71:269-277.


Characteristics influencing weight reduction among veterans in the MOVE!(R) Program.
Garvin JT, Marion LN, Narsavage GL, Finnegan L.
West J Nurs Res. 2015;37(1):50-65.


Gaussian process based modeling and experimental design for sensor calibration in drifting environments.
Geng ZY, Yang F, Chen X, Wu NQ.
Sens Actuators B Chem. 2015;216:321-331.


Towards high efficiency air-processed near-infrared responsive photovoltaics: bulk heterojunction solar cells based on PbS/CdS core-shell quantum dots and TiO2 nanorod arrays.
Gonfa BA, Kim MR, Delegan N, Tavares AC, Izquierdo R, Wu NQ, El Khakani MA, Ma D.
Nanoscale. 2015;7(22):10039-10049.


Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.
Goodson WH, III, Lowe L, Carpenter DO, Gilbertson M, Manaf AA, Lopez de Cerain SA, Lasfar A, Carnero A, Azqueta A, Amedei A, Charles AK, Collins AR, Ward A, Salzberg AC, Colacci A, Olsen AK, Berg A, Barclay BJ, Zhou BP, Blanco-Aparicio C, Baglole CJ, Dong C, Mondello C, Hsu CW, Naus CC, Yedjou C, Curran CS, Laird DW, Koch DC, Carlin DJ, Felsher DW, Roy D, Brown DG, Ratovitski E, Ryan EP, Corsini E, Rojas E, Moon EY, Laconi E, Marongiu F, Al-Mulla F, Chiaradonna F, Darroudi F, Martin FL, Van Schooten FJ, Goldberg GS, Wagemaker G, Nangami G, Calaf GM, Williams G, Wolf GT, Koppen G, Brunborg G, Kim LH, Krishnan H, Ab HH, Yasaei H, Sone H, Kondoh H, Salem HK, Hsu HY, Park HH, Koturbash I, Miousse IR, Scovassi AI, Klaunig JE, Vondracek J, Raju J, Roman J, Wise JP, Sr., Whitfield JR, Woodrick J, Christopher JA, Ochieng J, Martinez-Leal JF, Weisz J, Kravchenko J, Sun J, Prudhomme KR, Narayanan KB, Cohen-Solal KA, Moorwood K, Gonzalez L, Soucek L, Jian L, D'Abronzo LS, Lin LT, Li L, Gulliver L, McCawley LJ, Memeo L, Vermeulen L, Leyns L, Zhang L, Valverde M, Khatami M, Romano MF, Chapellier M, Williams MA, Wade M, Manjili MH, Lleonart M, Xia M, Gonzalez MJ, Karamouzis MV, Kirsch-Volders M, Vaccari M, Kuemmerle NB, Singh N, Cruickshanks N, Kleinstreuer N, van LN, Ahmed N, Ogunkua O, Krishnakumar PK, Vadgama P, Marignani PA, Ghosh PM, Ostrosky-Wegman P, Thompson P, Dent P, Heneberg P, Darbre P, Sing LP, Nangia-Makker P, Cheng QS, Robey RB, Al-Temaimi R, Roy R, ndrade-Vieira R, Sinha RK, Mehta R, Vento R, Di FR, Ponce-Cusi R, Dornetshuber-Fleiss R, Nahta R, Castellino RC, Palorini R, Abd HR, Langie SA, Eltom S, Brooks SA, Ryeom S, Wise SS, Bay SN, Harris SA, Papagerakis S, Romano S, Pavanello S, Eriksson S, Forte S, Casey SC, Luanpitpong S, Lee TJ, Otsuki T, Chen T, Massfelder T, Sanderson T, Guarnieri T, Hultman T, Dormoy V, Odero-Marah V, Sabbisetti V, Maguer-Satta V, Rathmell WK, Engstrom W, Decker WK, Bisson WH, Rojanasakul Y, Luqmani Y, Chen Z, Hu ZW.
Carcinogenesis. 2015;36 Suppl 1:S254-S296.

PMC4480130.

Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy.
He J, Yu JJ, Xu Q, Wang L, Zheng JZ, Liu LZ, Jiang BH.
Autophagy. 2015;11(2):373-384.

PMC4502709.

Selecting bioactive phenolic compounds as potential agents to inhibit proliferation and VEGF expression in human ovarian cancer cells.
He Z, Li B, Rankin GO, Rojanasakul Y, Chen YC.
Oncol Lett. 2015;9(3):1444-1450.

PMC4314987.

Effectiveness of community-based integrated care in frail COPD patients: a randomised controlled trial.
Hernandez C, Alonso A, Garcia-Aymerich J, Serra I, Marti D, Rodriguez-Roisin R, Narsavage GL, Carmen GM, Roca J, NEXES consortium.
NPJ.Prim Care Respir Med. 2015;25:15022

PMC4532156.

Analysis of affinities between specific biological ligands using atomic force microscopy.
Hu X, Dinu CZ.
Analyst. 2015;140(24):8118-8126.


Myricetin inhibits proliferation of cisplatin-resistant cancer cells through a p53-dependent apoptotic pathway.
Huang H, Chen AY, Ye X, Li BY, Rojanasakul Y, Rankin GO, Chen YC.
Int J Oncol. 2015;47(4):1494-1502.

PMC4583523.

Dietary compounds galangin and myricetin suppress ovarian cancer cell angiogenesis.
Huang H, Chen AY, Rojanasakul Y, Ye X, Rankin GO, Chen YC.
J Funct Foods. 2015;15:464-475.

PMC4476554.

Nitric oxide mediates bleomycin-induced angiogenesis and pulmonary fibrosis via regulation of VEGF.
Iyer AK, Ramesh V, Castro CA, Kaushik V, Kulkarni YM, Wright CA, Venkatadri R, Rojanasakul Y, Azad N.
J Cell Biochem. 2015;116(11):2484-2493.

PMC4586046.

Silica coating influences the corona and biokinetics of cerium oxide nanoparticles.
Konduru NV, Jimenez RJ, Swami A, Friend S, Castranova V, Demokritou P, Brain JD, Molina RM.
Part Fibre Toxicol. 2015;12(1):31

PMC4603643.

Chaetoglobosin K induces apoptosis and G2 cell cycle arrest through p53-dependent pathway in cisplatin-resistant ovarian cancer cells.
Li B, Gao Y, Rankin GO, Rojanasakul Y, Cutler SJ, Tu Y, Chen YC.
Cancer Lett. 2015;356(2 Pt B):418-433.

PMC4351971.

Semiconductor-based photocatalysts and photoelectrochemical cells for solar fuel generation: a review.
Li JT, Wu NQ.
Catalysis Science & Technology. 2015;5(3):1360-1384.


Plasmon-induced resonance energy transfer for solar energy conversion.
Li JT, Cushing SK, Meng FK, Senty TR, Bristow AD, Wu NQ.
Nature Photonics. 2015;9(9):601-+.


SLUG is required for SOX9 stabilization and functions to promote cancer stem cells and metastasis in human lung carcinoma.
Luanpitpong S, Li J, Manke A, Brundage KM, Ellis E, McLaughlin SL, Angsutararux P, Chanthra N, Voronkova M, Chen YC, Wang L, Chanvorachote P, Pei M, Issaragrisil S, Rojanasakul Y.
Oncogene. 2015; [Epub ahead of print]

PMC Journal - In Process.

Response to comment on "Appalachian mountaintop mining particulate matter induces neoplastic transformation of human bronchial epithelial cells and promotes tumor formation".
Luanpitpong S, Chen M, Knuckles T, Wen S, Luo JH, Ellis E, Hendryx MS, Rojanasakul Y.
Environ Sci Technol. 2015;49(15):9385


Effects of amorphous silica coating on cerium oxide nanoparticles induced pulmonary responses.
Ma J, Mercer RR, Barger M, Schwegler-Berry D, Cohen JM, Demokritou P, Castranova V.
Toxicol Appl Pharmacol. 2015;288(1):63-73.

PMC4579046.

Enhancement of solar hydrogen generation by synergistic interaction of La2Ti2O7 photocatalyst with plasmonic gold nanoparticles and reduced graphene oxide nanosheets.
Meng FK, Cushing SK, Li JT, Hao SM, Wu NQ.
ACS Catal. 2015;5(3):1949-1955.


Effects of nitrogen-doped multi-walled carbon nanotubes compared to pristine multi-walled carbon nanotubes on human small airway epithelial cells.
Mihalchik AL, Ding W, Porter DW, McLoughlin C, Schwegler-Berry D, Sisler JD, Stefaniak AB, Snyder-Talkington BN, Cruz-Silva R, Terrones M, Tsuruoka S, Endo M, Castranova V, Qian Y.
Toxicology. 2015;333:25-36.


Identification of TGF-beta receptor-1 as a key regulator of carbon nanotube-induced fibrogenesis.
Mishra A, Stueckle TA, Mercer RR, Derk R, Rojanasakul Y, Castranova V, Wang L.
Am J Physiol Lung Cell Mol Physiol. 2015;309(8):L821-L833.

PMC4609943.

Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death.
Narayanan KB, Ali M, Barclay BJ, Cheng Q, D'Abronzo L, Dornetshuber-Fleiss R, Ghosh PM, Gonzalez Guzman MJ, Luanpitpong S, Rojanasakul Y, Romano MF, Park HH, et.al.
Carcinogenesis. 2015;36 Suppl 1:S89-S110.

PMC4565614.

Inhalation exposure to carbon nanotubes (CNT) and carbon nanofibers (CNF): methodology and dosimetry.
Oberdorster G, Castranova V, Asgharian B, Sayre P.
J Toxicol Environ Health B Crit Rev. 2015;18(3-4):121-212.

PMC4706753.

AF1q is a novel TCF7 co-factor which activates CD44 and promotes breast cancer metastasis.
Park J, Schlederer M, Schreiber M, Kim S, Ice RJ, Merkel O, Bilban M, Hofbauer S, Addison JB, Zou J, Ji CY, Bunting S, Wang Z, Shoham M, Huang G, Bago-Horvath Z, Gibson LF, Rojanasakul Y, Remick SC, Ivanov AV, Pugacheva EN, Bunting K, Moriggl R, Kenner L, Tse WW.
OncoTarget. 2015;6(24):20697-20710.

PMC4653036.

Consumer exposures to laser printer-emitted engineered nanoparticles: A case study of life-cycle implications from nano-enabled products.
Pirela SV, Sotiriou GA, Bello D, Shafer M, Bunker KL, Castranova V, Thomas T, Demokritou P.
Nanotoxicology. 2015;9(6):760-768.

PMC4671491.

Carbon nanotubes induce apoptosis resistance of human lung epithelial cells through FLICE-inhibitory protein.
Pongrakhananon V, Luanpitpong S, Stueckle TA, Wang LY, Nimmannit U, Rojanasakul Y.
Toxicol Sci. 2015;143(2):499-511.

PMC4306727.

Evaluation of the pulmonary toxicity of ambient particulate matter from Camp Victory, Iraq.
Porter KL, Green FH, Harley RA, Vallyathan V, Castranova V, Waldron NR, Leonard SS, Nelson DE, Lewis JA, Jackson DA.
J Toxicol Environ Health A. 2015;78(23-24):1385-1408.

PMC4714599.

Effects of nickel-oxide nanoparticle pre-exposure dispersion status on bioactivity in the mouse lung.
Sager T, Wolfarth M, Keane M, Porter D, Castranova V, Holian A.
Nanotoxicology. 2015;1-11.


Small airway epithelial cells exposure to printer-emitted engineered nanoparticles induces cellular effects on human microvascular endothelial cells in an alveolar-capillary co-culture model.
Sisler JD, Pirela SV, Friend S, Farcas M, Schwegler-Berry D, Shvedova A, Castranova V, Demokritou P, Qian Y.
Nanotoxicology. 2015;9(6):769-779.


Multi-walled carbon nanotube-induced gene expression in vitro: concordance with in vivo studies.
Snyder-Talkington BN, Dong C, Zhao X, Dymacek J, Porter DW, Wolfarth MG, Castranova V, Qian Y, Guo NL.
Toxicology. 2015;328:66-74.

PMC4308557.

Differentiation of chemical reaction activity of various carbon nanotubes using redox potential: Classification by physical and chemical structures.
Tsuruoka S, Matsumoto H, Castranova V, Porter DW, Yanagisawa T, Saito N, Kobayashi S, Endo M.
Carbon. 2015;95:302-308.


Radical scavenging reaction kinetics with multiwalled carbon nanotubes.
Tsuruoka S, Matsumoto H, Koyama K, Akiba E, Yanagisawa T, Cassee FR, Saito N, Usui Y, Kobayashi S, Porter DW, Castranova V, Endo M.
Carbon. 2015;83:232-239.


Nitric oxide induces cancer stem cell-like phenotypes in human lung cancer cells.
Yongsanguanchai N, Pongrakhananon V, Mutirangura A, Rojanasakul Y, Chanvorachote P.
Am J Physiol Cell Physiol. 2015;308(2):C89-C100.


Investigation of band gap narrowing in nitrogen-doped La2Ti2O7 with transient absorption spectroscopy.
Yost BT, Cushing SK, Meng F, Bright J, Bas DA, Wu NQ, Bristow AD.
Phys Chem Chem Phys. 2015;17(46):31039-31043.


Microfluidic gradient device for studying mesothelial cell migration and the effect of chronic carbon nanotube exposure.
Zhang HY, Lohcharoenkal W, Sun JB, Li X, Wang LY, Wu NQ, Rojanasakul Y, Liu YX.
Journal of Micromechanics and Microengineering. 2015;25(7)


Band gap narrowing in nitrogen-doped La2Ti2O7 predicted by density-functional theory calculations.
Zhang JY, Dang WQ, Ao ZM, Cushing SK, Wu NQ.
Phys Chem Chem Phys. 2015;17(14):8994-9000.


Lignosulphonate-cellulose derived porous activated carbon for supercapacitor electrode.
Zhao ZH, Hao SM, Hao P, Sang YH, Manivannan A, Wu NQ, Liu H.
J Mater Chem A. 2015;3(29):15049-15056.


Tailoring plasmonic properties of gold nanohole arrays for surface-enhanced Raman scattering.
Zheng P, Cushing SK, Suri S, Wu NQ.
Phys Chem Chem Phys. 2015;17(33):21211-21219.

PMC4501901.

A gold nanohole array based surface-enhanced Raman scattering biosensor for detection of silver(i) and mercury(ii) in human saliva.
Zheng P, Li M, Jurevic RJ, Cushing SK, Liu Y, Wu NQ.
Nanoscale. 2015;7(25):11005-11012.

PMC4476066.

Cardiovascular effects in rats after intratracheal instillation of metal welding particles.
Zheng W, Antonini JM, Lin YC, Roberts JR, Kashon ML, Castranova V, Kan H.
Inhal Toxicol. 2015;27(1):45-53.


A surface-enhanced Raman scattering sensor integrated with battery-controlled fluidic device for capture and detection of trace small molecules.
Zhou QT, Meng GW, Zheng P, Cushing SK, Wu NQ, Huang Q, Zhu CH, Zhang Z, Wang ZW.
Sci Rep. 2015;5:12865

PMC4523941.

ZnO-nanotaper array sacrificial templated synthesis of noble-metal building-block assembled nanotube arrays as 3D SERS-substrates.
Zhu CH, Meng GW, Huang Q, Wang XJ, Qian YW, Hu XY, Tang HB, Wu NQ.
Nano Research. 2015;8(3):957-966.


Detection of the ovarian cancer biomarker CA-125 using chemiluminescence resonance energy transfer to graphene quantum dots.
Al-Ogaidi I, Gou HL, Aguilar ZP, Guo SW, Melconian AK, Al-Kazaz AK, Meng F, Wu NQ.
Chem Commun (Camb). 2014;50(11):1344-1346.


A gold@silica core-shell nanoparticle-based surface-enhanced Raman scattering biosensor for label-free glucose detection.
Al-Ogaidi I, Gou H, Al-Kazaz AK, Aguilar ZP, Melconian AK, Zheng P, Wu NQ.
Anal Chim.Acta. 2014;811:76-80.


Enzyme catalytic efficiency: a function of bio-nano interface reactions.
Campbell AS, Dong CB, Meng F, Hardinger J, Perhinschi G, Wu NQ, Dinu CZ.
ACS Appl Mater Interfaces. 2014;6(8):5393-5403.


Tumor-selective, futile redox cycle-induced bystander effects elicited by NQO1 bioactivatable radiosensitizing drugs in triple-negative breast cancers.
Cao L, Li LS, Spruell C, Xiao L, Chakrabarti G, Bey EA, Reinicke KE, Srougi MC, Moore Z, Dong Y, Vo P, Kabbani W, Yang CR, Wang X, Fattah F, Morales JC, Motea EA, Bornmann WG, Yordy JS, Boothman DA.
Antioxid Redox Signal. 2014;21(2):237-250.

PMC4060774.

Origin of strong excitation wavelength dependent fluorescence of graphene oxide.
Cushing SK, Li M, Huang F, Wu NQ.
ACS Nano. 2014;8(1):1002-1013.


Towards elucidating the effects of purified MWCNTs on human lung epithelial cells.
Dong C, EIdawud R, Sargent LM, Kashon ML, Lowry D, Rojanasakul Y, Dinu CZ.
Environ Sci Nano. 2014;1(6):95-603.

PMC4254708.

Preparation, characterization and application of magnetic Fe3O4-CS for the adsorption of orange I from aqueous solutions.
Du Y, Pei M, He Y, Yu F, Guo W, Wang L.
PLoS One. 2014;9(10):e108647

PMC4182735.

Real-time analysis of the effects of toxic, therapeutic and sub-therapeutic concentrations of digitoxin on lung cancer cells.
Eldawud R, Stueckle TA, Manivannan S, Elbaz H, Chen M, Rojanasakul Y, Dinu CZ.
Biosens Bioelectron. 2014;59C:192-199.


IL-1R signalling is critical for regulation of multi-walled carbon nanotubes-induced acute lung inflammation in C57Bl/6 mice.
Girtsman TA, Beamer CA, Wu NQ, Buford M, Holian A.
Nanotoxicology. 2014;8:17-27.

PMC4080682.

Air-processed depleted bulk heterojunction solar cells based on PbS/CdS core-shell quantum dots and TiO2 nanorod arrays.
Gonfa BA, Zhao HG, Li JT, Qiu JX, Saidani M, Zhang SQ, Izquierdo R, Wu NQ, El Khakani MA, Ma DL.
Solar Energy Materials and Solar Cells. 2014;124:67-74.


Network-based identification of biomarkers coexpressed with multiple pathways.
Guo NL, Wan YW.
Cancer Inform. 2014;13(Suppl 5):37-47.

PMC4218687.

Synthesis, characterization, and bioactivity of carboxylic acid-functionalized titanium dioxide nanobelts.
Hamilton RF, Wu NQ, Xiang C, Li M, Yang F, Wolfarth M, Porter DW, Holian A.
Part Fibre Toxicol. 2014;11(1):43

PMC4237951.

MicroRNA-29 induces cellular senescence in aging muscle through multiple signaling pathways.
Hu Z, Klein JD, Mitch WE, Zhang L, Martinez I, Wang XH.
Aging (Albany.NY). 2014;6(3):160-175.

PMC4012934.

Integrated DNA Copy Number and Gene Expression Regulatory Network Analysis of Non-small Cell Lung Cancer Metastasis.
Iranmanesh SM, Guo NL.
Cancer Inform. 2014;13(Suppl 5):13-23.

PMC4218678.

Nitrosothiol signaling and protein nitrosation in cell death.
Iyer AK, Rojanasakul Y, Azad N.
Nitric Oxide. 2014;42C:9-18.

PMC4258442.

The role of nodose ganglia in the regulation of cardiovascular function following pulmonary exposure to ultrafine titanium dioxide.
Kan H, Wu Z, Lin YC, Chen TH, Cumpston JL, Kashon ML, Leonard S, Munson AE, Castranova V.
Nanotoxicology. 2014;8:447-454.


Improving the risk assessment of lipophilic persistent environmental chemicals in breast milk.
Lehmann GM, Verner MA, Luukinen B, Henning C, Assimon SA, LaKind JS, McLanahan ED, Phillips LJ, Davis MH, Powers CM, Hines EP, Haddad S, Longnecker MP, Poulsen MT, Farrer DG, Marchitti SA, Tan YM, Swartout JC, Sagiv SK, Welsh C, Campbell JL, Jr., Foster WG, Yang RS, Fenton SE, Tornero-Velez R, Francis BM, Barnett JB, El-Masri HA, Simmons JE.
Crit Rev Toxicol. 2014;44(7):600-617.

PMC4115797.

Rejuvenation of chondrogenic potential in a young stem cell microenvironment.
Li J, Hansen KC, Zhang Y, Dong C, Dinu CZ, Dzieciatkowska M, Pei M.
Biomaterials. 2014;35(2):642-653.


Solar hydrogen generation by a CdS-Au-TiO2 sandwich nanorod array enhanced with Au nanoparticle as electron relay and plasmonic photosensitizer.
Li JT, Cushing SK, Zheng P, Senty T, Meng FK, Bristow AD, Manivannan A, Wu NQ.
J Am Chem Soc. 2014;136(23):8438-8449.


Protein nanoparticles as drug delivery carriers for cancer therapy.
Lohcharoenkal W, Wang LY, Chen YC, Rojanasakul Y.
Biomed Res Int. 2014;2014:180549

PMC3977416.

Role of H-Ras/ERK signaling in carbon nanotube-induced neoplastic-like transformation of human mesothelial cells.
Lohcharoenkal W, Wang LY, Stueckle TA, Park J, Tse WW, Dinu CZ, Rojanasakul Y.
Front Physiol. 2014;5:222

PMC4054652.

Luciferase reporter cells as a platform to detect SMAD-dependent collagen production.
Lohcharoenkal W, Liu Y, Wang LY, Yang Y, Rojanasakul Y.
J Biosci Bioeng. 2014;118(6):732-735.

PMC4253305.

Induction of stem-like cells with fibrogenic properties by carbon nanotubes and its role in fibrogenesis.
Luanpitpong S, Wang LY, Manke A, Castranova V, Yang Y, Martin KH, Ammer AG, Rojanasakul Y.
Nano Lett. 2014;14(6):3110-3116.

PMC4055043.

Appalachian mountaintop mining particulate matter induces neoplastic transformation of human bronchial epithelial cells and promotes tumor formation.
Luanpitpong S, Chen M, Knuckles T, Wen S, Luo JH, Ellis E, Hendryx MS, Rojanasakul Y.
Environ Sci Technol. 2014;48(21):12912-12919.

PMC4224494.

Induction of stem-like cells with malignant properties by chronic exposure of human lung epithelial cells to single-walled carbon nanotubes.
Luanpitpong S, Wang LY, Castranova V, Rojanasakul Y.
Part Fibre Toxicol. 2014;11(1):22

PMC4040122.

The effects of carbon nanotubes on lung and dermal cellular behaviors.
Luanpitpong S, Wang LY, Rojanasakul Y.
Nanomedicine (Lond). 2014;9(6):895-912.

PMC4710349.

Caveolin-1 regulates lung cancer stem-like cell induction and p53 inactivation in carbon nanotube-driven tumorigenesis.
Luanpitpong S, Wang LY, Stueckle TA, Tse WW, Chen YC, Rojanasakul Y.
OncoTarget. 2014;5(11):3541-3554.

PMC4116501.

Interactive effects of cerium oxide and diesel exhaust nanoparticles on inducing pulmonary fibrosis.
Ma JY, Young SH, Mercer RR, Barger MW, Schwegler-Berry D, Ma JK, Castranova V.
Toxicol Appl Pharmacol. 2014;278(2):135-147.


Metallic nickel nanoparticles may exhibit higher carcinogenic potential than fine particles in JB6 cells.
Magaye R, Zhou Q, Bowman L, Zou B, Mao G, Xu J, Castranova V, Zhao J, Ding M.
PLoS One. 2014;9(4):e92418

PMC3972196.

Effect of fiber length on carbon nanotube-induced fibrogenesis.
Manke A, Luanpitpong S, Dong C, Wang LY, He X, Battelli LA, Derk R, Stueckle TA, Porter DW, Sager T, Gou H, Dinu CZ, Wu NQ, Mercer RR, Rojanasakul Y.
Int J Mol Sci. 2014;15(5):7444-7461.

PMC4057682.

Review of poly (ADP-ribose) polymerase (PARP) mechanisms of action and rationale for targeting in cancer and other diseases.
Morales JC, Li LS, Fattah FJ, Dong Y, Bey EA, Patel M, Gao JM, Boothman DA.
Crit Rev Eukaryot Gene Expr. 2014;24(1):15-28.


Band gap modulation of functionalized metal-organic frameworks.
Musho T, Li J, Wu NQ.
Phys Chem Chem Phys. 2014;16(43):23646-23653.


Feasibility study: home telemonitoring for patients with lung cancer in a mountainous rural area.
Petitte TM, Narsavage GL, Chen YJ, Coole C, Forth T, Frick KD.
Oncol Nurs Forum. 2014;41(2):153-161.

PMC4332839.

Development and characterization of an exposure platform suitable for physico-chemical, morphological and toxicological characterization of printer-emitted particles (PEPs).
Pirela SV, Pyrgiotakis G, Bello D, Thomas T, Castranova V, Demokritou P.
Inhal Toxicol. 2014;26(7):400-408.

PMC4383100.

Monosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradation.
Pongrakhananon V, Stueckle TA, Wang HY, O'Doherty GA, Dinu CZ, Chanvorachote P, Rojanasakul Y.
Biochem Pharmacol. 2014;88(1):23-35.

PMC3970117.

Alterations in cardiomyocyte function after pulmonary treatment with stainless steel welding fume in rats.
Popstojanov R, Antonini JM, Salmen R, Ye M, Zheng W, Castranova V, Fekedulegn DB, Kan H.
J Toxicol Environ Health A. 2014;77(12):705-715.


Combining COPD with clinical, pathological and demographic information refines prognosis and treatment response prediction of non-small cell lung cancer.
Putila J, Guo NL.
PLoS One. 2014;9(6):e100994

PMC4072724.

Therapeutic applications of carbon nanotubes: opportunities and challenges.
Rogers-Nieman GM, Dinu CZ.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2014;6(4):327-337.


Effect of multi-walled carbon nanotube surface modification on bioactivity in the C57Bl/6 mouse model.
Sager TM, Wolfarth MG, Friend S, Hubbs AF, Hamilton RF, Wu NQ, Yang F, Porter DW, Holian A.
Nanotoxicology. 2014;8:317-327.

PMC4669410.

Promotion of lung adenocarcinoma following inhalation exposure to multi-walled carbon nanotubes.
Sargent LM, Porter DW, Staska LM, Hubbs AF, Lowry DT, Battelli LA, Siegrist KJ, Kashon ML, Mercer RR, Bauer AK, Chen BT, Salisbury JL, Frazer D, McKinney W, Andrew ME, Tsuruoka S, Endo M, Fluharty KL, Castranova V, Reynolds SH.
Part Fibre Toxicol. 2014;11(1):3

PMC3895742.

Occupational safety and health criteria for responsible development of nanotechnology.
Schulte PA, Geraci CL, Murashov V, Kuempel ED, Zumwalde RD, Castranova V, Hoover MD, Hodson L, Martinez KF.
J Nanopart Res. 2014;16:2153

PMC3890581.

Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year post exposure comparisons.
Shvedova AA, Yanamala N, Kisin ER, Tkach AV, Murray AR, Hubbs A, Chirila MM, Keohavong P, Sycheva LP, Kagan VE, Castranova V.
Am J Physiol Lung Cell Mol Physiol. 2014;306(2):L170-82.

PMC3920208.

Genotoxicity of multi-walled carbon nanotubes at occupationally relevant doses.
Siegrist KJ, Reynolds SH, Kashon ML, Lowry DT, Dong C, Hubbs AF, Young SH, Salisbury JL, Porter DW, Benkovic SA, McCawley MA, Keane MJ, Mastovich JT, Bunker KL, Cena LG, Sparrow MC, Sturgeon JL, Dinu CZ, Sargent LM.
Part Fibre Toxicol. 2014;11:6

PMC3923549.

S-nitrosylation of FLICE inhibitory protein determines its interaction with RIP1 and activation of NF-kappaB.
Talbott SJ, Luanpitpong S, Stehlik C, Azad N, Iyer AK, Wang LY, Rojanasakul Y.
Cell Cycle. 2014;13(12):1948-1957.

PMC4111758.

A new stochastic Kriging method for modeling multi-source exposure-response data in toxicology studies.
Wang K, Chen X, Yang F, Porter DW, Wu NQ.
ACS Sustain.Chem Eng. 2014;2(7):1581-1591.

PMC4105196.

Neoplastic-like transformation effect of single-walled and multi-walled carbon nanotubes compared to asbestos on human lung small airway epithelial cells.
Wang LY, Stueckle TA, Mishra A, Derk R, Meighan T, Castranova V, Rojanasakul Y.
Nanotoxicology. 2014;8(5):485-507.

PMC4599578.

Dispersion method for safety research on manufactured nanomaterials.
Wu W, Ichihara G, Suzuki Y, Izuoka K, Oikawa-Tada S, Chang J, Sakai K, Miyazawa K, Porter D, Castranova V, Kawaguchi M, Ichihara S.
Ind Health. 2014;52(1):54-65.

PMC4202770.

The Yin: An adverse health perspective of nanoceria: uptake, distribution, accumulation, and mechanisms of its toxicity.
Yokel RA, Hussain S, Garantziotis S, Demokritou P, Castranova V, Cassee FR.
Environ Sci Nano. 2014;1(5):406-428.

PMC4167411.

Effects of pore structure on performance of an activated-carbon supercapacitor electrode recycled from scrap waste tires.
Zhi MJ, Yang F, Meng FK, Li MQ, Manivannan A, Wu NQ.
Acs Sustainable Chemistry & Engineering. 2014;2(7):1592-1598.


Electrospun activated carbon nanofibers for supercapacitor electrodes.
Zhi MJ, Liu SH, Hong ZL, Wu NQ.
Rsc Advances. 2014;4(82):43619-43623.


Dual detection of cancer biomarker CA125 using absorbance and electrochemical methods.
Al-Ogaidi I, Aguilar ZP, Suri S, Gou H, Wu NQ.
Analyst. 2013;138(19):5647-5653.

PMC3816148.

Reactive oxygen species-mediated p38 MAPK regulates carbon nanotube-induced fibrogenic and angiogenic responses.
Azad N, Iyer AK, Wang LY, Liu Y, Lu Y, Rojanasakul Y.
Nanotoxicology. 2013;7(2):157-168.

PMC4089498.

Catalase abrogates beta-Lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers.
Bey EA, Reinicke KE, Srougi MC, Varnes M, Anderson VE, Pink JJ, Li LS, Patel M, Cao L, Moore Z, Rommel A, Boatman M, Lewis C, Euhus DM, Bornmann WG, Buchsbaum DJ, Spitz DR, Gao J, Boothman DA.
Mol Cancer Ther. 2013;12(10):2110-2120.

PMC3807805.

Interlaboratory evaluation of rodent pulmonary responses to engineered nanomaterials: The NIEHS NanoGo Consortium.
Bonner JC, Silva RM, Taylor AJ, Brown JM, Hilderbrand SC, Castranova V, Porter DW, Elder A, Oberdorster G, Harkema JR, Bramble LA, Kavanagh TJ, Botta D, Nel AE, Pinkerton KE.
Environ Health Perspect. 2013;121(6):676-682.

PMC3672912.

BioNano engineered hybrids for hypochlorous acid generation.
Campbell AS, Dong CB, Dordick JS, Dinu CZ.
Process Biochemistry. 2013;48(9):1355-1360.


Occupational nanosafety considerations for carbon nanotubes and carbon nanofibers.
Castranova V, Schulte PA, Zumwalde RD.
Acc Chem Res. 2013;46(3):642-649.


An in vivo and in vitro toxicological characterisation of realistic nanoscale CeO(2) inhalation exposures.
Demokritou P, Gass S, Pyrgiotakis G, Cohen JM, Goldsmith W, McKinney W, Frazer D, Ma J, Schwegler-Berry D, Brain J, Castranova V.
Nanotoxicology. 2013;7:1338-1350.

PMC4438163.

Effects of acid treatment on structure, properties and biocompatibility of carbon nanotubes.
Dong CB, Campell AS, Eldawud R, Perhinschi G, Rojanasakul Y, Dinu CZ.
Appl Surf Sci. 2013;264:261-268.


Exposure to carbon nanotubes leads to changes in the cellular biomechanics.
Dong CB, Kashon ML, Lowry D, Dordick JS, Reynolds SH, Rojanasakul Y, Sargent LM, Dinu CZ.
Adv Healthc Mater. 2013;2(7):945-951.


Molecular trucks and complementary tracks for bionanotechnological applications.
Dong CB, Dinu CZ.
Curr Opin Biotechnol. 2013;24(4):612-619.


Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology.
Erdely A, Dahm M, Chen BT, Zeidler-Erdely PC, Fernback JE, Birch ME, Evans DE, Kashon ML, Deddens JA, Hulderman T, Bilgesu SA, Battelli LA, Schwegler-Berry D, Leonard HD, McKinney W, Frazer DG, Antonini JM, Porter DW, Castranova V, Schubauer-Berigan MK.
Part Fibre Toxicol. 2013;10(1):53

PMC4015290.

A bootstrapping-based statistical procedure for multivariate calibration of sensor arrays.
Geng ZY, Yang F, Li MQ, Wu NQ.
Sensor Actuat B-Chem. 2013;188:440-453.


Enzyme-based formulations for decontamination: current state and perspectives.
Grover N, Dinu CZ, Kane RS, Dordick JS.
Appl Microbiol Biotechnol. 2013;97(8):3293-3300.


Purification and sidewall functionalization of multiwalled carbon nanotubes and resulting bioactivity in two macrophage models.
Hamilton RF, Jr., Xiang C, Li M, Ka I, Yang F, Ma D, Porter DW, Wu NQ, Holian A.
Inhal Toxicol. 2013;25(4):199-210.

PMC4127292.

Engineered nanoparticles (ENM) cause lung pathology by increasing lysosomal membrane permeability and activation of the NLRP3 inflammasome in macrophages.
Holian A, Hamilton R, Girtsman T, Migliaccio C, Buford M, Shaw P, Herritt L, Mitra S, Sager T, Porter DW, Wu NQ.
Eur J Clin Invest. 2013;43:5-5.


Understanding physical activity outcomes as a function of teen smoking cessation.
Horn KA, Branstetter SA, Zhang J, Jarrett TD, O'Hara-Tompkins NM, Anesetti-Rothermel A, Olfert M, Richards T, Dino GA.
J Adolesc Health. 2013;53(1):125-131.


Nanotechnology: toxicologic pathology.
Hubbs AF, Sargent LM, Porter DW, Sager TM, Chen BT, Frazer DG, Castranova V, Sriram K, Nurkiewicz TR, Reynolds SH, Battelli LA, Schwegler-Berry D, McKinney W, Fluharty KL, Mercer RR.
Toxicol Pathol. 2013;4(2):395-409.

PMC4665093.

The effect of the physicochemical properties of bioactive electroconductive hydrogels on the growth and proliferation of attachment dependent cells.
Kotanen CN, Wilson AN, Dong C, Dinu CZ, Justin GA, Guiseppi-Elie A.
Biomaterials. 2013;34(27):6318-6327.


Toxicity of lunar dust assessed in inhalation-exposed rats.
Lam CW, Scully RR, Zhang Y, Renne RA, Hunter RL, McCluskey RA, Chen BT, Castranova V, Driscoll KE, Gardner DE, McClellan RO, Cooper BL, McKay DS, Marshall L, James JT.
Inhal Toxicol. 2013;25(12):661-678.


Parental influences on 7-9 year olds' physical activity: a conceptual model.
Leary JM, Ice CL, Dino GA, Loprinzi P, Cottrell LA.
Prev Med. 2013;56(5):341-344.


The toxicity of the N-hydroxy and 6-hydroxy metabolites of 3,4-dichloropropionanilide does not depend on calcium release-activated calcium channel inhibition.
Lewis TL, Holaskova I, Barnett JB.
Toxicol Sci. 2013;131(2):395-405.

PMC3551424.

Plasmon-induced photonic and energy-transfer enhancement of solar water splitting by a hematite nanorod array.
Li JT, Cushing SK, Zheng P, Meng F, Chu D, Wu NQ.
Nat Commun. 2013;4:2651


Ag@Cu2O core-shell nanoparticles as visible-light plasmonic photocatalysts.
Li JT, Cushing SK, Bright J, Meng FK, Senty TR, Zheng P, Bristow AD, Wu NQ.
ACS Catal. 2013;3(1):47-51.


Plasmonic nanorice antenna on triangle nanoarray for surface-enhanced Raman scattering detection of hepatitis B virus DNA.
Li M, Cushing SK, Liang H, Suri S, Ma D, Wu NQ.
Anal Chem. 2013;85(4):2072-2078.


Fluorescent aptamer-functionalized graphene oxide biosensor for label-free detection of mercury(II).
Li M, Zhou X, Ding WQ, Guo SW, Wu NQ.
Biosens Bioelectron. 2013;41:889-893.


Detection of lead (II) with a "turn-on" fluorescent biosensor based on energy transfer from CdSe/ZnS quantum dots to graphene oxide.
Li M, Zhou XJ, Guo SW, Wu NQ.
Biosens Bioelectron. 2013;43:69-74.


Photocatalytic hydrogen generation enhanced by band gap narrowing and improved charge carrier mobility in AgTaO3 by compensated co-doping.
Li M, Zhang JY, Dang WQ, Cushing SK, Guo D, Wu NQ, Yin PG.
Phys Chem Chem Phys. 2013;15(38):16220-16226.


Three-dimensional hierarchical plasmonic nano-architecture enhanced surface-enhanced Raman scattering immunosensor for cancer biomarker detection in blood plasma.
Li M, Cushing SK, Zhang J, Suri S, Evans R, Petros WP, Gibson LF, Ma D, Liu Y, Wu NQ.
ACS Nano. 2013;7(6):4967-4976.

PMC3732798.

Nanostructured sensors for detection of heavy metals: A Review.
Li M, Gou HL, Al-Ogaidi I, Wu NQ.
Acs Sustainable Chemistry & Engineering. 2013;1(7):713-723.


Selective stamp bonding of PDMS microfluidic devices to polymer substrates for biological applications.
Li X, Wu NQ, Rojanasakul Y, Liu YX.
Sensor Actuat A-Physical. 2013;193:186-192.


Asymmetric silver "nanocarrot" structures: solution synthesis and their asymmetric plasmonic resonances.
Liang HY, Rossouw D, Zhao HG, Cushing SK, Shi HL, Korinek A, Xu HX, Rosei F, Wang WZ, Wu NQ, Botton GA, Ma DL.
J Am Chem Soc. 2013;135(26):9616-9619.


Hemoglobin-based oxygen carrier mitigates transfusion-mediated pancreas cancer progression.
Lo KK, Bey EA, Patra B, Benson DD, Boothman DA, Silliman CC, Barnett CC, Jr.
Ann Surg Oncol. 2013;20(6):2073-2077.

PMC3699326.

Chronic exposure to carbon nanotubes induces invasion of human mesothelial cells through matrix netalloproteinase-2.
Lohcharoenkal W, Wang LY, Stueckle TA, Dinu CZ, Castranova V, Liu Y, Rojanasakul Y.
ACS Nano. 2013;24(7):7711-7723.

PMC3875633.

Regulation of apoptosis by Bcl-2 cysteine oxidation in human lung epithelial cells.
Luanpitpong S, Chanvorachote P, Stehlik C, Tse WW, Callery PS, Wang LY, Rojanasakul Y.
Mol Biol Cell. 2013;24(6):858-869.

PMC3596255.

Mechanisms of nanoparticle-induced oxidative stress and toxicity.
Manke A, Wang LY, Rojanasakul Y.
Biomed Res Int. 2013;2013:942916

PMC3762079.

Pulmonary toxicity and fibrogenic response of carbon nanotubes.
Manke A, Wang LY, Rojanasakul Y.
Toxicol Mech Methods. 2013;23(3):196-206.

PMC4593477.

Solar hydrogen generation by nanoscale p-n junction of p-type molybdenum disulfide/n-type nitrogen-doped reduced graphene oxide.
Meng F, Li J, Cushing SK, Zhi M, Wu NQ.
J Am Chem Soc. 2013;135(28):10286-10289.


Photocatalytic water oxidation by hematite/reduced graphene oxide composites.
Meng FK, Li JT, Cushing SK, Bright J, Zhi MJ, Rowley JD, Hong ZL, Manivannan A, Bristow AD, Wu NQ.
ACS Catal. 2013;3(4):746-751.


Photocatalytic generation of hydrogen with visible-light nitrogen-doped lanthanum titanium oxides.
Meng FK, Li JT, Hong ZL, Zhi MJ, Sakla A, Xiang CC, Wu NQ.
Catalysis Today. 2013;199:48-52.


Distribution and fibrotic response following inhalation exposure to multi-walled carbon nanotubes.
Mercer RR, Scabilloni JF, Hubbs AF, Battelli LA, McKinney W, Friend S, Wolfarth MG, Andrew ME, Castranova V, Porter DW.
Part Fibre Toxicol. 2013;10(1):33

PMC3733770.

Extrapulmonary transport of MWCNT following inhalation exposure.
Mercer RR, Scabilloni JF, Hubbs AF, Wang LY, Battelli LA, McKinney W, Castranova V, Porter DW.
Part Fibre Toxicol. 2013;10(1):38

PMC3750633.

Oxidative stress and dermal toxicity of iron oxide nanoparticles in vitro.
Murray AR, Kisin E, Inman A, Young SH, Muhammed M, Burks T, Uheida A, Tkach A, Waltz M, Castranova V, Fadeel B, Kagan VE, Riviere JE, Monteiro-Riviere N, Shvedova AA.
Cell Biochem Biophys. 2013;67(2):461-476.


A multi-stakeholder perspective on the use of alternative test strategies for nanomaterial safety assessment.
Nel AE, Nasser E, Godwin H, Avery D, Bahadori T, Bergeson L, Beryt E, Bonner JC, Boverhof D, Carter J, Castranova V, Deshazo JR, Hussain SM, Kane AB, Klaessig F, Kuempel E, Lafranconi M, Landsiedel R, Malloy T, Miller MB, Morris J, Moss K, Oberdorster G, Pinkerton K, Pleus RC, Shatkin JA, Thomas R, Tolaymat T, Wang A, Wong J.
ACS Nano. 2013;7(8):6422-6433.

PMC4004078.

Parent health risk and support for child physical activity.
Nolan JA, Cottrell LA, Dino GA.
Am J Health Behav. 2013;37(1):32-42.


The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells.
Pacurari M, Addison JB, Bondalapati N, Wan YW, Luo D, Qian Y, Castranova V, Ivanov AV, Guo NL.
Int J Oncol. 2013;43(2):548-560.

PMC3775564.

Acute pulmonary dose-responses to inhaled multi-walled carbon nanotubes.
Porter DW, Hubbs AF, Chen BT, McKinney W, Mercer RR, Wolfarth MG, Battelli LA, Wu NQ, Sriram K, Leonard S, Andrew ME, Willard P, Tsuruoka S, Endo M, Tsukada T, Munekane F, Frazer DG, Castranova V.
Nanotoxicology. 2013;7:1179-1194.


Differential mouse pulmonary dose- and time course-responses to titanium dioxide nanospheres and nanobelts.
Porter DW, Wu NQ, Hubbs AF, Mercer R, Funk K, Meng F, Li J, Wolfarth M, Battelli LA, Friend S, Andrew ME, Hamilton R, Sriram K, Yang F, Castranova V, Holian A.
Toxicol Sci. 2013;131(1):179-193.

PMC3537123.

Pulmonary and cardiovascular responses of rats to inhalation of silver nanoparticles.
Roberts JR, McKinney W, Kan H, Krajnak K, Frazer DG, Thomas TA, Waugh S, Kenyon A, Maccuspie RI, Hackley VA, Castranova V.
J Toxicol Environ Health A. 2013;76(11):651-668.


Lung toxicity and biodistribution of Cd/Se-ZnS quantum dots with different surface functional groups after pulmonary exposure in rats.
Roberts JR, Antonini JM, Porter DW, Chapman RS, Scabilloni JF, Young SH, Schwegler-Berry D, Castranova V, Mercer RR.
Part Fibre Toxicol. 2013;10:5

PMC3599433.

Linking JNK-STAT3-Akt signaling axis to EZH2 phosphorylation: a novel pathway of carcinogenesis.
Rojanasakul Y.
Cell Cycle. 2013;12(2):202

PMC3575446.

Investigation of the pulmonary bioactivity of double-walled carbon nanotubes.
Sager TM, Wolfarth MW, Battelli LA, Leonard SS, Andrew ME, Steinbach T, Endo M, Tsuruoka S, Porter DW, Castranova V.
J Toxicol Environ Health A. 2013;76(15):922-936.


Titanium dioxide nanoparticles: a review of current toxicological data.
Shi H, Magaye R, Castranova V, Zhao J.
Part Fibre Toxicol. 2013;10(1):15

PMC3637140.

Systematic analysis of multiwalled carbon nanotube-induced cellular signaling and gene expression in human small airway epithelial cells.
Snyder-Talkington BN, Pacurari M, Dong C, Leonard SS, Schwegler-Berry D, Castranova V, Qian Y, Guo NL.
Toxicol Sci. 2013;133(1):79-89.

PMC3627550.

System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses.
Snyder-Talkington BN, Dymacek J, Porter DW, Wolfarth MG, Mercer RR, Pacurari M, Denvir J, Castranova V, Qian Y, Guo NL.
Toxicol Appl Pharmacol. 2013;272(2):476-489.

PMC4017347.

Multi-walled carbon nanotubes induce human microvascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells.
Snyder-Talkington BN, Schwegler-Berry D, Castranova V, Qian Y, Guo NL.
Part Fibre Toxicol. 2013;10:35

PMC3750368.

Graphene oxide, but not fullerenes, targets immunoproteasomes and suppresses antigen presentation by dendritic cells.
Tkach AV, Yanamala N, Stanley S, Shurin MR, Shurin GV, Kisin ER, Murray AR, Pareso S, Khaliullin T, Kotchey GP, Castranova V, Mathur S, Fadeel B, Star A, Kagan VE, Shvedova AA.
Small. 2013;9(9-10):1686-1690.

PMC4009732.

A new approach to design safe CNTs with an understanding of redox potential.
Tsuruoka S, Cassee FR, Castranova V.
Part Fibre Toxicol. 2013;10(1):44

PMC3848781.

Human cytochrome P450 1A1 structure and utility in understanding drug and xenobiotic metabolism.
Walsh AA, Szklarz GD, Scott EE.
J Biol Chem. 2013;288(18):12932-12943.

PMC3642336.

Two-stage experimental design for dose-response modeling in toxicology studies.
Wang K, Yang F, Porter DW, Wu NQ.
Acs Sustainable Chem Eng. 2013;1(9):1119-1128.


The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Wang LY, He X, Szklarz GD, Bi Y, Rojanasakul Y, Ma Q.
Arch Biochem Biophys. 2013;537(1):31-38.


Interlaboratory evaluation of in vitro cytotoxicity and inflammatory responses to engineered nanomaterials: the NIEHS Nano GO Consortium.
Xia T, Hamilton RF, Bonner JC, Crandall ED, Elder A, Fazlollahi F, Girtsman TA, Kim K, Mitra S, Ntim SA, Orr G, Tagmount M, Taylor AJ, Telesca D, Tolic A, Vulpe CD, Walker AJ, Wang X, Witzmann FA, Wu NQ, Xie Y, Zink JI, Nel A, Holian A.
Environ Health Perspect. 2013;121(6):683-690.

PMC3672931.

Experimental and statistical analysis of surface charge, aggregation and adsorption behaviors of surface-functionalized titanium dioxide nanoparticles in aquatic system.
Xiang CC, Yang F, Li M, Jaridi M, Wu NQ.
J Nanopart Res. 2013;15(1)


A reduced graphene oxide/Co3O4 composite for supercapacitor electrode.
Xiang CC, Li M, Zhi MJ, Manivannan A, Wu NQ.
J Power Sources. 2013;226:65-70.


Dynamic calibration of electrochemical sensor for accelerated analyte quantification.
Yang F, Geng ZY, Koneru A, Zhi MJ, Li HL, Wu NQ.
IEEE Sens J. 2013;13(4):1192-1199.


Whole-body nanoparticle aerosol inhalation exposures.
Yi J, Chen BT, Schwegler-Berry D, Frazer D, Castranova V, McBride C, Knuckles TL, Stapleton PA, Minarchick VC, Nurkiewicz TR.
J Vis Exp. 2013;(75)

PMC3679583.

TRAIL and proteasome inhibitors combination induces a robust apoptosis in human malignant pleural mesothelioma cells through Mcl-1 and Akt protein cleavages.
Yuan BZ, Chapman J, Ding M, Wang J, Jiang B, Rojanasakul Y, Reynolds SH.
BMC Cancer. 2013;13(1):140

PMC3665596.

Apoptosis induced by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS generation through both extrinsic and intrinsic apoptosis pathways.
Zhao J, Bowman L, Magaye R, Leonard SS, Castranova V, Ding M.
Int J Oncol. 2013;42(4):1349-1359.


Nanostructured carbon-metal oxide composite electrodes for supercapacitors: a review.
Zhi MJ, Xiang CC, Li JT, Li M, Wu NQ.
Nanoscale. 2013;5(1):72-88.


Single cell gel electrophoresis assay (comet assay) for evaluating nanoparticles-induced DNA damage in cells.
Bowman L, Castranova V, Ding M.
Methods Mol Biol. 2012;906:415-422.


Additive effects of exogenous IL-12 supplementation and antibiotic treatment in infection prophylaxis.
Boyce BM, Lindsey BA, Clovis NB, Smith ES, Hobbs GR, Hubbard DF, Emery SE, Barnett JB, Li BY.
J Orthop Res. 2012;30(2):196-202.

PMC3699881.

Gender differences in cigarette smoking, social correlates and cessation among adolescents.
Branstetter SA, Blosnich JR, Dino GA, Nolan J, Horn KA.
Addict Behav. 2012;37(6):739-742.

PMC3334461.

Multi-walled carbon nanotubes: sampling criteria and aerosol characterization.
Chen BT, Schwegler-Berry D, McKinney W, Stone S, Cumpston JL, Friend S, Porter DW, Castranova V, Frazer DG.
Inhal Toxicol. 2012;24(12):798-820.


Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells.
Chunhacha P, Pongrakhananon V, Rojanasakul Y, Chanvorachote P.
Am J Physiol Cell Physiol. 2012;302(9):C1284-C1292.

PMC3774262.

Photocatalytic activity enhanced by plasmonic resonant energy transfer from metal to semiconductor.
Cushing SK, Li J, Meng F, Senty TR, Suri S, Zhi M, Li M, Bristow AD, Wu NQ.
J Am Chem Soc. 2012;134(36):15033-15041.


Luciferase reporter system for studying the effect of nanoparticles on gene expression.
Ding M, Bowman L, Castranova V.
Methods Mol Biol. 2012;906:403-414.


Antibacterial and surface-enhanced Raman scattering (SERS) activities of AgCl cubes synthesized by pulsed laser ablation in liquid.
Dong CB, Yan ZJ, Kokx J, Chrisey DB, Dinu CZ.
Applied Surface Science. 2012;258(23):9218-9222.


Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cells.
Elbaz HA, Stueckle TA, Wang HY, O'Doherty GA, Lowry DT, Sargent LM, Wang LY, Dinu CZ, Rojanasakul Y.
Toxicol Appl Pharmacol. 2012;258(1):51-60.

PMC3254807.

Digitoxin and its analogs as novel cancer therapeutics.
Elbaz HA, Stueckle TA, Tse WW, Rojanasakul Y, Dinu CZ.
Exp Hematol Oncol. 2012;1(1):4

PMC3506989.

Apaf-1 deficiency confers resistance to ultraviolet-induced apoptosis in mouse embryonic fibroblasts by disrupting reactive oxygen species amplification production and mitochondrial pathway.
Feng R, Han J, Ziegler J, Yang M, Castranova V.
Free Radic Biol Med. 2012;52(5):889-897.


Perhydrolase-nanotube paint composites with sporicidal and antiviral activity.
Grover N, Douaisi MP, Borkar IV, Lee L, Dinu CZ, Kane RS, Dordick JS.
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Laccase- and chloroperoxidase-nanotube paint composites with bactericidal and sporicidal activity.
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Enzyme Microb Technol. 2012;50(6-7):271-279.


Crosslink density of a biomimetic poly(HEMA)-based hydrogel influences growth and proliferation of attachment dependent RMS 13 cells.
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Multiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosis.
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Pathway-based identification of a smoking associated 6-gene signature predictive of lung cancer risk and survival.
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NLRP3 inflammasome activation in murine alveolar macrophages and related lung pathology is associated with MWCNT nickel contamination.
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Prenatal cadmium exposure alters postnatal immune cell development and function.
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Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the nuclear factor erythroid 2-related factor 2 pathway.
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Prenatal cadmium exposure produces persistent changes to thymus and spleen cell phenotypic repertoire as well as the acquired immune response.
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Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.
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An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis.
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Cancer Res. 2012;72(12):3038-3047.


Respiratory and olfactory cytotoxicity of inhaled 2,3-pentanedione in Sprague-Dawley rats.
Hubbs AF, Cumpston AM, Goldsmith WT, Battelli LA, Kashon ML, Jackson MC, Frazer DG, Fedan JS, Goravanahally MP, Castranova V, Kreiss K, Willard PA, Friend S, Schwegler-Berry D, Fluharty KL, Sriram K.
Am J Pathol. 2012;181(3):829-844.


Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells.
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Pulmonary exposure of rats to ultrafine titanium dioxide enhances cardiac protein phosphorylation and substance P synthesis in nodose ganglia.
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Nanotoxicology. 2012;6:736-745.


AC927, a sigma receptor ligand, blocks methamphetamine-induced release of dopamine and generation of reactive oxygen species in NG108-15 cells.
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Mol Pharmacol. 2012;81(3):299-308.

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An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages.
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Nanoparticle inhalation alters systemic arteriolar vasoreactivity through sympathetic and cyclooxygenase-mediated pathways.
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Nanotoxicology. 2012;6:724-735.


Development of risk-based nanomaterial groups for occupational exposure control.
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Photoelectrochemical performance enhanced by a nickel oxide-hematite p-n junction photoanode.
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Chem Commun (Camb). 2012;48(66):8213-8215.


Detection of adenosine triphosphate with an aptamer biosensor based on surface-enhanced Raman scattering.
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Anal Chem. 2012;84(6):2837-2842.


Fingerprinting photoluminescence of functional groups in graphene oxide.
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J Mater Chem. 2012;22(44):23374-23379.


Shape-dependent surface-enhanced Raman scattering in gold-Raman probe-silica sandwiched nanoparticles for biocompatible applications.
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Defective calcium inactivation causes long QT in obese insulin-resistant rat.
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Am J Physiol Heart Circ Physiol. 2012;302(4):H1013-H1022.

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Mitochondrial superoxide mediates doxorubicin-induced keratinocyte apoptosis through oxidative modification of ERK and Bcl-2 ubiquitination.
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Biochem Pharmacol. 2012;83(12):1643-1654.

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Nitrosothiol signaling in anoikis resistance and cancer metastasis.
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Predictors of survival in patients with non-small cell lung cancer.
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Oncol Nurs Forum. 2012;39(6):609-616.


Induction of pulmonary fibrosis by cerium oxide nanoparticles.
Ma JY, Mercer RR, Barger MW, Schwegler-Berry D, Scabilloni J, Ma JK, Castranova V.
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Pulmonary and cardiovascular responses of rats to inhalation of a commercial antimicrobial spray containing titanium dioxide nanoparticles.
McKinney W, Jackson M, Sager TM, Reynolds JS, Chen BT, Afshari A, Krajnak K, Waugh S, Johnson C, Mercer RR, Frazer DG, Thomas TA, Castranova V.
Inhal Toxicol. 2012;24(7):447-457.


Multifunctional role of Bcl-2 in malignant transformation and tumorigenesis of Cr(VI)-transformed lung cells.
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PLoS One. 2012;7(5):e37045

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Visible light photocatalytic activity of nitrogen-doped La2Ti2O7 nanosheets originating from band gap narrowing.
Meng FK, Hong ZL, Arndt J, Li M, Zhi MJ, Yang F, Wu NQ.
Nano Research. 2012;5(3):213-221.


Assessment of pulmonary fibrogenic potential of multiwalled carbon nanotubes in human lung cells.
Mishra A, Rojanasakul Y, Chen BT, Castranova V, Mercer RR, Wang LY.
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Cell permeability, migration, and reactive oxygen species induced by multiwalled carbon nanotubes in human microvascular endothelial cells.
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J Toxicol Environ Health A. 2012;75(2):112-128.

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Single-cell gel electrophoresis (Comet) assay in nano-genotoxicology.
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Glutathione conjugation of busulfan produces a hydroxyl radical-trapping dehydroalanine metabolite.
Peer CJ, Younis IR, Leonard SS, Gannett PM, Minarchick VC, Kenyon AJ, Rojanasakul Y, Callery PS.
Xenobiotica. 2012;42(12):1170-1177.


The role of physical therapists in smoking cessation: Opportunities for improving treatment outcomes.
Pignataro RM, Ohtake PJ, Swisher AK, Dino GA.
Phys Ther. 2012;92(5):757-766.


Differential oxidation of two thiophene-containing regioisomers to reactive metabolites by cytochrome P450 2C9.
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Chem Res Toxicol. 2012;25(4):895-903.

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In situ construction of a titanate-silver nanoparticle-titanate sandwich nanostructure on a metallic titanium surface for bacteriostatic and biocompatible implants.
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J Mater Chem. 2012;22(36):19151-19160.


Pulmonary toxicity, distribution, and clearance of intratracheally instilled silicon nanowires in rats.
Roberts JR, Mercer RR, Chapman RS, Cohen GM, Bangsaruntip S, Schwegler-Berry D, Scabilloni JF, Castranova V, Antonini JM, Leonard SS.
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Gene disruption of the calcium channel Orai1 results in inhibition of osteoclast and osteoblast differentiation and impairs skeletal development.
Robinson LJ, Mancarella S, Songsawad D, Tourkova IL, Barnett JB, Gill DL, Soboloff J, Blair HC.
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Focused actions to protect carbon nanotube workers.
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Am J Ind Med. 2012;55(5):395-411.


New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformatics.
Snyder-Talkington BN, Qian Y, Castranova V, Guo NL.
J Toxicol Environ Health B Crit Rev. 2012;15(7):468-492.

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Impairment of coronary arteriolar endothelium-dependent dilation after multi-walled carbon nanotube inhalation: a time-course study.
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Chronic occupational exposure to arsenic induces carcinogenic gene signaling networks and neoplastic transformation in human lung epithelial cells.
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Damage associated molecular pattern molecule-induced microRNAs (DAMPmiRs) induction in human peripheral blood mononuclear cells.
Unlu S, Tang S, Wang E, Martinez I, Tang D, Bianchi ME, Zeh HJ, Lotze MT.
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Predictors of retention and BMI loss or stabilization in obese youth enrolled in a weight loss intervention.
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Obes Res Clin Pract. 2012;6(4):e330-e339.

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Signaling pathway-based identification of extensive prognostic gene signatures for lung adenocarcinoma.
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A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis.
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Selective filling of nanowells in nanowell arrays fabricated using polystyrene nanosphere lithography with cytochrome P450 enzymes.
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Nanotechnology. 2012;23(38):385101

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Reduced graphene oxide/titanium dioxide composites for supercapacitor electrodes: shape and coupling effects.
Xiang CC, Li M, Zhi MJ, Manivannan A, Wu NQ.
J Mater Chem. 2012;22(36):19161-19167.


Highly conductive electrospun carbon nanofiber/MnO2 coaxial nano-cables for high energy and power density supercapacitors.
Zhi MJ, Manivannan A, Meng FK, Wu NQ.
J Power Sources. 2012;208:345-353.


Electrospun La0.8Sr0.2MnO(3) nanofibers for a high-temperature electrochemical carbon monoxide sensor.
Zhi MJ, Koneru A, Yang F, Manivannan A, Li JT, Wu NQ.
Nanotechnology. 2012;23(30):305501


Beyond reach and effectiveness: evaluating the Not-On-Tobacco (N-O-T) program in West Virginia from 2000 to 2005.
Anesetti-Rothermel A, Noerachmanto N, Horn KA, Dino GA.
Health Promot Pract. 2011;13(4):506-514.


miR-190-Mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis.
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Toxicol Sci. 2011;123(2):411-420.

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Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1.
Carpenter RL, Jiang Y, Jing Y, He J, Rojanasakul Y, Liu LZ, Jiang BH.
Biochem Biophys Res Commun. 2011;414(3):533-538.


Bioactivity of oil dispersant used in the deepwater horizon cleanup operation.
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J Toxicol Environ Health A. 2011;74(21):1367


Overview of current toxicological knowledge of engineered nanoparticles.
Castranova V.
J Occup Environ Med. 2011;53(6 Suppl):S14-7


Origin of localized surface plasmon resonances in thin silver film over nanosphere patterns.
Cushing SK, Hornak LA, Lankford J, Liu YX, Wu NQ.
Appl Phys A Mater Sci Process. 2011;103(4):955-958.


Intraoperative imaging guidance for sentinel node biopsy in melanoma using a mobile gamma camera.
Dengel LT, More MJ, Judy PG, Petroni GR, Smolkin ME, Rehm PK, Majewski S, Williams MB, Slingluff CL, Jr.
Ann Surg. 2011;253(4):774-778.


Adolescent smoking cessation: promising strategies and evidence-based recommendations.
Dino GA, Pignataro R, Breland A, Murray PJ, Horn KA.
Adolesc Med State Art Rev. 2011;22(3):614-xiv.


Kinesin I ATPase manipulates biohybrids formed from tubulin and carbon nanotubes.
Dinu CZ, Bale SS, Dordick JS.
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Identification of systemic markers from a pulmonary carbon nanotube exposure.
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J Occup Environ Med. 2011;53(6 Suppl):S80-S86.


Optimum design of sensor arrays via simulation-based multivariate calibration.
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Sensor Actuat B-Chem. 2011;156(2):854-862.


A novel network model identified a 13-gene lung cancer prognostic signature.
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Int J Comput Biol Drug Des. 2011;4(1):19-39.

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Effects of physical activity on teen smoking cessation.
Horn KA, Dino GA, Branstetter SA, Zhang J, Noerachmanto N, Jarrett T, Taylor M.
Pediatrics. 2011;128(4):e801-e811.


Nanotoxicology--a pathologist's perspective.
Hubbs AF, Mercer RR, Benkovic SA, Harkema J, Sriram K, Schwegler-Berry D, Goravanahally MP, Nurkiewicz TR, Castranova V, Sargent LM.
Toxicol Pathol. 2011;39(2):301-324.


Antioxidant c-FLIP inhibits Fas ligand-induced NF-{kappa}B activation in a phosphatidylinositol 3-Kinase/Akt-dependent manner.
Iyer AK, Azad N, Talbot S, Stehlik C, Lu B, Wang LY, Rojanasakul Y.
J Immunol. 2011;187(6):3256-3266.

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Genotoxicity of carbon nanofibers: Are they potentially more or less dangerous than carbon nanotubes or asbestos?
Kisin ER, Murray AR, Sargent LM, Lowry D, Chirila M, Siegrist KJ, Schwegler-Berry D, Leonard S, Castranova V, Fadeel B, Kagan VE, Shvedova AA.
Toxicol Appl Pharmacol. 2011;252(1):1-10.


Acute effects of COREXIT EC9500A on cardiovascular functions in rats.
Krajnak K, Kan H, Waugh S, Miller GR, Johnson C, Roberts JR, Goldsmith WT, Jackson M, McKinney W, Frazer D, Kashon ML, Castranova V.
J Toxicol Environ Health A. 2011;74(21):1397-1404.


Single-crystalline Ni(OH)(2) and NiO nanoplatelet arrays as supercapacitor electrodes.
Li JT, Zhao W, Huang FQ, Manivannan A, Wu NQ.
Nanoscale. 2011;3(12):5103-5109.


Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of beta-lapachone for pancreatic cancer therapy.
Li LS, Bey EA, Dong Y, Meng J, Patra B, Yan J, Xie XJ, Brekken RA, Barnett CC, Jr., Bornmann WG, Gao J, Boothman DA.
Clin Cancer Res. 2011;17(2):275-285.


Size-dependent energy transfer between CdSe/ZnS quantum dots and gold nanoparticles.
Li M, Cushing SK, Wang QY, Shi XD, Hornak LA, Hong ZL, Wu NQ.
J Phys Chem Lett. 2011;2(17):2125-2129.


Detection of mercury(II) by quantum dot/DNA/gold nanoparticle ensemble based nanosensor via nanometal surface energy transfer.
Li M, Wang Q, Shi X, Hornak LA, Wu NQ.
Anal Chem. 2011;83(18):7061-7065.


Random KNN feature selection -- a fast and stable alternative to Random Forests.
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Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1alpha pathway.
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Hydroxyl radical mediates cisplatin-induced apoptosis in human hair follicle dermal papilla cells and keratinocytes through Bcl-2-dependent mechanism.
Luanpitpong S, Nimmannit U, Chanvorachote P, Leonard SS, Pongrakhananon V, Wang LY, Rojanasakul Y.
Apoptosis. 2011;16(8):769-782.


Cerium oxide nanoparticle-induced pulmonary inflammation and alveolar macrophage functional change in rats.
Ma JY, Zhao H, Mercer RR, Barger MW, Rao M, Meighan T, Schwegler-Berry D, Castranova V, Ma JK.
Nanotoxicology. 2011;5:312-325.


miR-29 and miR-30 regulate B-Myb expression during cellular senescence.
Martinez I, Cazalla D, Almstead LL, Steitz JA, DiMaio D.
Proc Natl Acad Sci USA. 2011;108(2):522-527.

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B-Myb, cancer, senescence, and microRNAs.
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Cancer Res. 2011;71(16):5370-5373.

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MicroRNAs and senescence.
Martinez I, Almstead LL, DiMaio D.
Aging (Albany.NY). 2011;3(2):77-78.

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Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes.
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Pulmonary particulate matter and systemic microvascular dysfunction.
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Res Rep Health Eff Inst. 2011;(164):3-48.


Raw single-walled carbon nanotube-induced cytotoxic effects in human bronchial epithelial cells: comparison to asbestos.
Pacurari M, Schwegler-Berry D, Friend S, Leonard SS, Mercer RR, Vallyathan V, Castranova V.
Toxicol Environ Chem. 2011;93(5):1045-1072.


Multi-walled carbon nanotube-induced gene expression in the mouse lung: association with lung pathology.
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Association of arsenic exposure with lung cancer incidence rates in the United States.
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Combining clinical, pathological, and demographic factors refines prognosis of lung cancer: a population-based study.
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Pulmonary effects after acute inhalation of oil dispersant (COREXIT EC9500A) in rats.
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J Toxicol Environ Health A. 2011;74(21):1381-1396.


Hydrogen peroxide inhibits non-small cell lung cancer cell anoikis through the inhibition of caveolin-1 degradation.
Rungtabnapa P, Nimmannit U, Halim H, Rojanasakul Y, Chanvorachote P.
Am J Physiol Cell Physiol. 2011;300(2):C235-C245.

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Single-walled carbon nanotube-induced mitotic disruption.
Sargent LM, Hubbs AF, Young SH, Kashon ML, Dinu CZ, Salisbury JL, Benkovic SA, Lowry DT, Murray AR, Kisin ER, Siegrist KJ, Battelli LA, Mastovich J, Sturgeon JL, Bunker KL, Shvedova AA, Reynolds SH.
Mutat Res. 2011;745(1-2):28-37.


The dual roles of c-Jun NH2-terminal kinase signaling in Cr(VI)-induced apoptosis in JB6 cells.
Son YO, Hitron JA, Cheng S, Budhraja A, Zhang Z, Guo NL, Lee JC, Shi X.
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Nanomaterials in humans: identification, characteristics, and potential damage.
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Neurotoxicity following acute inhalation exposure to the oil dispersant COREXIT EC9500A.
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C5'-Alkyl substitution effects on digitoxigenin alpha-l-glycoside cancer cytotoxicity.
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Stereochemical survey of digitoxin monosaccharides: new anticancer analogues with enhanced apoptotic activity and growth inhibitory effect on human non-small cell lung cancer cell.
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Synthesis and evaluation of the alpha-D-/alpha-L-rhamnosyl and amicetosyl digitoxigenin oligomers as anti-tumor agents.
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Carbon nanotubes induce malignant transformation and tumorigenesis of human lung epithelial cells.
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Dispersal state of multiwalled carbon nanotubes elicits profibrogenic cellular responses that correlate with fibrogenesis biomarkers and fibrosis in the murine lung.
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Ensuring accountability in public health prevention research: evaluating the Prevention Research Centers Program at the Centers for Disease Control and Prevention.
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Decreased dissolution of ZnO by iron doping yields nanoparticles with reduced toxicity in the rodent lung and zebrafish embryos.
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Engineering of a microfluidic cell culture platform embedded with nanoscale features.
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Pulmonary inflammation induced by office dust and the relation to 1 3--glucan using different extraction techniques.
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Toxicol Environ Chem. 2011;93(4):806-823.


Towards controlled synthesis and better understanding of highly luminescent PbS/CdS core/shell quantum dots.
Zhao HG, Chaker M, Wu NQ, Ma DL.
J Mater Chem. 2011;21(24):8898-8904.


Toxicology of nanomaterials used in nanomedicine.
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J Toxicol Environ Health B Crit Rev. 2011;14(8):593-632.


The role of calcium release activated calcium channels in osteoclast differentiation.
Zhou Y, Lewis TL, Robinson LJ, Brundage KM, Schafer R, Martin KH, Blair HC, Soboloff J, Barnett JB.
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Role of oxidative/nitrosative stress-mediated Bcl-2 regulation in apoptosis and malignant transformation.
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Nitric oxide-mediated bcl-2 stabilization potentiates malignant transformation of human lung epithelial cells.
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Evaluating macrophages in immunotoxicity testing.
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Microprocessor of microRNAs: regulation and potential for therapeutic intervention.
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Beta-lapachone micellar nanotherapeutics for non-small cell lung cancer therapy.
Blanco E, Bey EA, Khemtong C, Yang SG, Setti-Guthi J, Chen H, Kessinger CW, Carnevale KA, Bornmann WG, Boothman DA, Gao J.
Cancer Res. 2010;70(10):3896-3904.

PMC2873165.

Bionanoconjugate-based composites for decontamination of nerve agents.
Borkar IV, Dinu CZ, Zhu G, Kane RS, Dordick JS.
Biotechnol Prog. 2010;26(6):1622-1628.


Differential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomes.
Bryan NB, Dorfleutner A, Kramer SJ, Yun C, Rojanasakul Y, Stehlik C.
J Inflamm (Lond). 2010;7:23

PMC2887861.

Nanoparticles-containing spray can aerosol: characterization, exposure assessment, and generator design.
Chen BT, Afshari A, Stone S, Jackson M, Schwegler-Berry D, Frazer DG, Castranova V, Thomas TA.
Inhal Toxicol. 2010;22(13):1072-1082.


The development and psychometric analysis of the short-form Pulmonary Functional Status Scale (PFSS-11).
Chen YJ, Narsavage GL, Culp SL, Weaver TE.
Res Nurs Health. 2010;33(6):477-485.


Oleanane triterpenoid CDDO-Me inhibits growth and induces apoptosis in prostate cancer cells through a ROS-dependent mechanism.
Deeb D, Gao X, Jiang H, Janic B, Arbab AS, Rojanasakul Y, Dulchavsky SA, Gautam SC.
Biochem Pharmacol. 2010;79(3):350-360.

PMC2822351.

Enzyme-based nanoscale composites for use as active decontamination surfaces.
Dinu CZ, Zhu G, Bale SS, Anand G, Reeder PJ, Sanford K, Whited G, Kane RS, Dordick JS.
Adv Funct Mater. 2010;20(3):392-398.


Prostate cancer radiosensitization through poly(ADP-Ribose) polymerase-1 hyperactivation.
Dong Y, Bey EA, Li LS, Kabbani W, Yan J, Xie XJ, Hsieh JT, Gao J, Boothman DA.
Cancer Res. 2010;70(20):8088-8096.

PMC2955807.

Challenges in assessing nanomaterial toxicology: a personal perspective.
Geraci CL, Castranova V.
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2010;2(6):569-577.


Interleukin 12 a key immunoregulatory cytokine in infection applications.
Hamza T, Barnett JB, Li BY.
Int J Mol Sci. 2010;11(3):789-806.

PMC2869233.

Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/beta-catenin signaling in the thymus resulting in altered thymocyte development.
Hanson ML, Brundage KM, Schafer R, Tou JC, Barnett JB.
Toxicol Appl Pharmacol. 2010;242(2):136-145.

PMC2789900.

Subcellular localization of the amide class herbicide 3,4-dichloropropionanilide (DCPA) in T cells and hepatocytes.
Hanson ML, Peer CJ, Brundage RA, Callery PS, Brundage KM, Schafer R, Eremin S, Barnett JB.
J Toxicol Environ Health A. 2010;73(1):1-4.

PMC2888467.

Significant increase in phenacetin oxidation on L382V substitution in human cytochrome P450 1A2.
Huang Q, Szklarz GD.
Drub Metab Dispos. 2010;38(7):1039-1045.

PMC2908983.

Cell-based detection of Bacillus Cereus anthrax simulant using cell impedance sensing.
Hynes A, Mohanraj B, Schiele N, Corr DT, Plopper GE, Dinu CZ, Chrisey DB.
Sensor Letters. 2010;8(3):528-533.


A direct comparison of the anticancer activities of digitoxin MeON-Neoglycosides and O-Glycosides: oligosaccharide chain length-dependent induction of Caspase-9-mediated apoptosis.
Iyer AK, Zhou M, Azad N, Elbaz H, Wang LY, Rogalsky DK, Rojanasakul Y, O'Doherty GA, Langenhan JM.
ACS Med Chem Lett. 2010;1(7):326-330.

PMC2916185.

Nanoparticle inhalation impairs coronary microvascular reactivity via a local reactive oxygen species-dependent mechanism.
LeBlanc AJ, Moseley AM, Chen BT, Frazer DG, Castranova V, Nurkiewicz TR.
Cardiovasc Toxicol. 2010;10(1):27-36.

PMC2825710.

Phosphatidylinositol-3-kinase/akt regulates bleomycin-induced fibroblast proliferation and collagen production.
Lu YJ, Azad N, Wang LY, Iyer AK, Castranova V, Jiang BH, Rojanasakul Y.
Am J Respir Cell Mol Biol. 2010;42(4):432-441.

PMC2848736.

Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1.
Luanpitpong S, Talbott SJ, Rojanasakul Y, Nimmannit U, Pongrakhananon V, Wang LY, Chanvorachote P.
J Biol Chem. 2010;285(50):38832-38840.

PMC2998081.

Distribution and persistence of pleural penetrations by multi-walled carbon nanotubes.
Mercer RR, Hubbs AF, Scabilloni JF, Wang LY, Battelli LA, Schwegler-Berry D, Castranova V, Porter DW.
Part Fibre Toxicol. 2010;7:28

PMC2958975.

A 12-gene genomic instability signature predicts clinical outcomes in multiple cancer types.
Mettu RK, Wan YW, Habermann JK, Ried T, Guo NL.
Int J Biol Markers. 2010;25(4)

PMC3155635.

Pulmonary inflammation after intraperitoneal administration of ultrafine titanium dioxide (TiO2) at rest or in lungs primed with lipopolysaccharide.
Moon C, Park HJ, Choi YH, Park EM, Castranova V, Kang JL.
J Toxicol Environ Health A. 2010;73(5):396-409.


DNA double-strand breaks by asbestos, silica, and titanium dioxide: possible biomarker of carcinogenic potential?
Msiska Z, Pacurari M, Mishra A, Leonard SS, Castranova V, Vallyathan V.
Am J Respir Cell Mol Biol. 2010;43(2):210-219.


Single- and multi-wall carbon nanotubes versus asbestos: are the carbon nanotubes a new health risk to humans?
Pacurari M, Castranova V, Vallyathan V.
J Toxicol Environ Health A. 2010;73(5):378-395.


Antistaphylococcal nanocomposite films based on enzyme-nanotube conjugates.
Pangule RC, Brooks SJ, Dinu CZ, Bale SS, Salmon SL, Zhu G, Metzger DW, Kane RS, Dordick JS.
ACS Nano. 2010;4(7):3993-4000.

PMC2919614.

Curcumin sensitizes non-small cell lung cancer cell anoikis through reactive oxygen species-mediated Bcl-2 downregulation.
Pongrakhananon V, Nimmannit U, Luanpitpong S, Rojanasakul Y, Chanvorachote P.
Apoptosis. 2010;15(5):574-585.


Mouse pulmonary dose- and time course-responses induced by exposure to multi-walled carbon nanotubes.
Porter DW, Hubbs AF, Mercer RR, Wu NQ, Wolfarth MG, Sriram K, Leonard SS, Battelli LA, Schwegler-Berry D, Friend S, Andrew ME, Chen BT, Tsuruoka S, Endo M, Castranova V.
Toxicology. 2010;269(2-3):136-147.


Perfluorooctane sulfonate (PFOS) induces reactive oxygen species (ROS) production in human microvascular endothelial cells: role in endothelial permeability.
Qian Y, Ducatman AM, Ward R, Leonard SS, Bukowski VC, Guo NL, Shi XL, Vallyathan V, Castranova V.
J Toxicol Environ Health A. 2010;73(12):819-836.

PMC3107001.

A population-based gene signature is predictive of breast cancer survival and chemoresponse.
Rathnagiriswaran S, Wan YW, Abraham J, Castranova V, Qian Y, Guo NL.
Int J Oncol. 2010;36(3):607-616.

PMC3103999.

Regulation of bone turnover by calcium-regulated calcium channels.
Robinson LJ, Blair HC, Barnett JB, Zaidi M, Huang CL.
Ann NY Acad Sci. 2010;1192:351-357.


Concept of assessing nanoparticle hazards considering nanoparticle dosemetric and chemical/biological response metrics.
Rushton EK, Jiang J, Leonard SS, Eberly S, Castranova V, Biswas P, Elder A, Han X, Gelein R, Finkelstein J, Oberdorster G.
J Toxicol Environ Health A. 2010;73(5):445-461.

PMC3884809.

Potential pulmonary effects of engineered carbon nanotubes: in vitro genotoxic effects.
Sargent LM, Reynolds SH, Castranova V.
Nanotoxicology. 2010;4:396-408.


Algorithm for haplotype resolution and block partitioning for partial XOR-genotype data.
Sazonova N, Sazonov E, Harner EJ.
J Biomed Inform. 2010;43(1):51-59.


Effects of titanium dioxide nanoparticle exposure on neuroimmune responses in rat airways.
Scuri M, Chen BT, Castranova V, Reynolds JS, Johnson VJ, Samsell L, Walton C, Piedimonte G.
J Toxicol Environ Health A. 2010;73(20):1353-1369.

PMC3655524.

Mitochondrial dysfunction and loss of Parkinson's disease-linked proteins contribute to neurotoxicity of manganese-containing welding fumes.
Sriram K, Lin GX, Jefferson AM, Roberts JR, Wirth O, Hayashi Y, Krajnak KM, Soukup JM, Ghio AJ, Reynolds SH, Castranova V, Munson AE, Antonini JM.
FASEB J. 2010;24(12):4989-5002.


A breast cancer prognostic signature predicts clinical outcomes in multiple tumor types.
Wan YW, Qian Y, Rathnagiriswaran S, Castranova V, Guo NL.
Oncol Rep. 2010;24(2):489-494.

PMC3095949.

Hybrid models identified a 12-gene signature for lung cancer prognosis and chemoresponse prediction.
Wan YW, Sabbagh E, Raese RA, Qian Y, Luo D, Denvir J, Vallyathan V, Castranova V, Guo NL.
PLoS One. 2010;5(8):e12222

PMC2923187.

Tuning the charge-transfer property of PbS-quantum dot/TiO2-nanobelt nanohybrids via quantum confinement.
Wang DF, Zhao HG, Wu NQ, El Khakani MA, Ma DL.
J Phys Chem Lett. 2010;1(7):1030-1035.


Direct fibrogenic effects of dispersed single-walled carbon nanotubes on human lung fibroblasts.
Wang LY, Mercer RR, Rojanasakul Y, Qiu AJ, Lu YJ, Scabilloni JF, Wu NQ, Castranova V.
J Toxicol Environ Health A. 2010;73(5):410-422.


Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies.
Wang LY, Castranova V, Mishra A, Chen B, Mercer RR, Schwegler-Berry D, Rojanasakul Y.
Part Fibre Toxicol. 2010;7:31-41.

PMC2970581.

Quantitative techniques for assessing and controlling the dispersion and biological effects of multiwalled carbon nanotubes in mammalian tissue culture cells.
Wang X, Xia T, Ntim SA, Ji Z, George S, Meng H, Zhang H, Castranova V, Mitra S, Nel AE.
ACS Nano. 2010;4:7241-7252.

PMC3899393.

Shape-enhanced photocatalytic activity of single-crystalline anatase TiO(2) (101) nanobelts.
Wu NQ, Wang J, Tafen DN, Wang H, Zheng JG, Lewis JP, Liu XG, Leonard SS, Manivannan A.
J Am Chem Soc. 2010;132(19):6679-6685.

PMC2878616.

Laser ablation induced agglomeration of Cu nanoparticles in sodium dodecyl sulfate aqueous solution.
Yan ZJ, Bao RQ, Dinu CZ, Huang Y, Caruso AN, Chrisey DB.
J Optoelectron Adv M. 2010;12(3):437-439.


Excimer laser production, assembly, sintering, and fragmentation of novel fullerene-like permalloy particles in liquid.
Yan ZJ, Bao RQ, Huang Y, Caruso AN, Qadri SB, Dinu CZ, Chrisey DB.
Journal of Physical Chemistry C. 2010;114(9):3869-3873.


Tuning the shape and thermoelectric property of PbTe nanocrystals by bismuth doping.
Zhang Q, Sun T, Cao F, Li M, Hong M, Yuan J, Yan Q, Hng HH, Wu NQ, Liu X.
Nanoscale. 2010;2(7):1256-1259.


Tungsten carbide-cobalt particles activate Nrf2 and its downstream target genes in JB6 cells possibly by ROS generation.
Zhang XD, Zhao JS, Bowman LL, Shi XG, Castranova V, Ding M.
J Environ Pathol Toxicol Oncol. 2010;29(1):31-40.


Temperature and impurity concentration effects on degradation of nickel/yttria-stabilised zirconia anode in PH3-containing coal syngas.
Zhi MJ, Cayan FN, Celik I, Gemmen R, Pakalapati SR, Wu NQ.
Fuel Cells. 2010;10(1):174-180.


Iron oxide nanoparticles induce human microvascular endothelial cell permeability through reactive oxygen species production and microtubule remodeling.
Apopa PL, Qian Y, Shao R, Guo NL, Schwegler-Berry D, Pacurari M, Porter DW, Shi XL, Vallyathan V, Castranova V, Flynn DC.
Part Fibre Toxicol. 2009;6:1

PMC2632982.

Methods to analyze S-nitrosylation of proteins involved in apoptosis.
Azad N, Iyer AK, Rojanasakul Y.
Methods Mol Biol. 2009;559:117-130.


Toxicology of nanomaterials: permanent interactive learning.
Borm PJ, Castranova V.
Part Fibre Toxicol. 2009;6:28

PMC2774283.

Beyond quitting: predictors of teen smoking cessation, reduction and acceleration following a school-based intervention.
Branstetter SA, Horn KA, Dino GA, Zhang J.
Drug Alcohol Depend. 2009;99(1-3):160-168.

PMC2683731.

Activation of inflammasomes requires intracellular redistribution of the apoptotic speck-like protein containing a caspase recruitment domain.
Bryan NB, Dorfleutner A, Rojanasakul Y, Stehlik C.
J Immunol. 2009;182(5):3173-3182.

PMC2652671.

JNK1 activation predicts the prognostic outcome of the human hepatocellular carcinoma.
Chang QS, Chen J, Beezhold KJ, Castranova V, Shi XL, Chen F.
Mol Cancer. 2009;8:64

PMC2732591.

Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer.
Chang QS, Zhang Y, Beezhold KJ, Bhatia D, Zhao H, Chen J, Castranova V, Shi XL, Chen F.
J Hepatol. 2009;50(2):323-333.

PMC4417500.

Curcumin sensitizes lung cancer cells to cisplatin-induced apoptosis through superoxide anion-mediated Bcl-2 degradation.
Chanvorachote P, Pongrakhananon V, Wannachaiyasit S, Luanpitpong S, Rojanasakul Y, Nimmannit U.
Cancer Invest. 2009;27(6):6241-635.


Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1.
Chanvorachote P, Nimmannit U, Lu YJ, Talbott SJ, Jiang BH, Rojanasakul Y.
J Biol Chem. 2009;284(41):28476-28484.

PMC2788896.

Beyond apoptosis of JNK1 in liver cancer.
Chen F, Castranova V.
Cell Cycle. 2009;8(8):1145-1147.


JNK1, a Potential Therapeutic Target for Hepatocellular Carcinoma.
Chen F, Beezhold KJ, Castranova V.
Biochim Biophys Acta. 2009;1796(2):242-251.


Overlapping signature genes between hepatocellular carcinoma and intrahepatic cholangiocarcinoma.
Chen F, Li S, Castranova V.
Eur J Gastroenterol Hepatol. 2009;21(11):1320-1321.


Signature genes for both hepatoblastoma and hepatocellular carcinoma.
Chen F, Li S, Castranova V.
Eur J Gastroenterol Hepatol. 2009;21(10):1220-1222.


Size-dependent effects of tungsten carbide-cobalt particles on oxygen radical production and activation of cell signaling pathways in murine epidermal cells.
Ding M, Kisin ER, Zhao J, Bowman LL, Lu Y, Jiang BH, Leonard SS, Vallyathan V, Castranova V, Murray AR, Fadeel B, Shvedova AA.
Toxicol Appl Pharmacol. 2009;241(3):260-268.


POLY 177-Enzyme-nanotube-based composites used for antifouling, chemical, and biological decontamination.
Dinu CZ, Zhu GY, Whited G, Sanford K, Kane R, Dordick JS.
Abstr Pap Am Chem S. 2009;238


Tubulin encapsulation of carbon nanotubes into functional hybrid assemblies.
Dinu CZ, Bale SS, Zhu G, Dordick JS.
Small. 2009;5(3):310-315.


The limits of testing particle-mediated oxidative stress in vitro in predicting diverse pathologies; relevance for testing of nanoparticles.
Donaldson K, Borm PJ, Castranova V, Gulumian M.
Part Fibre Toxicol. 2009;6:13

PMC2685764.

Intratumoral delivery of beta-lapachone via polymer implants for prostate cancer therapy.
Dong Y, Chin SF, Blanco E, Bey EA, Kabbani W, Xie XJ, Bornmann WG, Boothman DA, Gao J.
Clin Cancer Res. 2009;15(1):131-139.

PMC2845536.

Cross-talk between lung and systemic circulation during carbon nanotube respiratory exposure. Potential biomarkers.
Erdely A, Hulderman T, Salmen R, Liston A, Zeidler-Erdely PC, Schwegler-Berry D, Castranova V, Koyama S, Kim YA, Endo M, Simeonova PP.
Nano Lett. 2009;9(1):36-43.


Coal dust alters beta-naphthoflavone-induced aryl hydrocarbon receptor nuclear translocation in alveolar type II cells.
Ghanem MM, Battelli LA, Law BF, Castranova V, Kashon ML, Nath J, Hubbs AF.
Part Fibre Toxicol. 2009;6:21

PMC2732588.

Impact and interactions between smoking and traditional prognostic factors in lung cancer progression.
Guo NL, Tosun K, Horn KA.
Lung Cancer. 2009;66(3):386-392.

PMC2783345.

The role of p53 in silica-induced cellular and molecular responses associated with carcinogenesis.
Gwinn MR, Leonard SS, Sargent LM, Lowry DT, McKinstry KT, Meighan T, Reynolds SH, Kashon ML, Castranova V, Vallyathan V.
J Toxicol Environ Health A. 2009;72(23):1509-1519.


The gene expression signature of genomic instability in breast cancer is an independent predictor of clinical outcome.
Habermann JK, Doering J, Hautaniemi S, Roblick UJ, Bundgen NK, Nicorici D, Kronenwett U, Rathnagiriswaran S, Mettu RK, Ma Y, Kruger S, Bruch HP, Auer G, Guo NL, Ried T.
Int J Cancer. 2009;124(7):1552-1564.

PMC2707256.

Particle length-dependent titanium dioxide nanomaterials toxicity and bioactivity.
Hamilton RF, Wu NQ, Porter DW, Buford M, Wolfarth M, Holian A.
Part Fibre Toxicol. 2009;6:35

PMC2806338.

JavaStat: a Java/R-based statistical computing environment.
Harner EJ, Luo DJ, Tan J.
Comput Stat. 2009;24(2):295-302.


The dose effect of pulmonary rehabilitation on physical activity, perceived exertion, and quality of life.
Hassanein SE, Narsavage GL.
J Cardiopulm Rehabil Prev. 2009;29(4):255-260.


Potential effects of active parental consent: Enrolling teen smokers into a school-based cessation program.
Horn KA, Branstetter SA, Dino GA, Jarrett TD, Tworek C, Zhang JJ.
Nicotine Tob Res. 2009;11(11):1359-1367.


Who wants to quit? Characteristics of American Indian youth who seek smoking cessation intervention.
Horn KA, Noerachmanto N, Dino GA, Manzo K, Brayboy M.
J Community Health. 2009;34(2):153-163.


From high tech to high touch: integrating community voices in mobile mammography outreach.
Kennedy S, Stephens S, Tephabock K, Brown PK, Davis P, Keresztury J, Narsavage GL.
WV Med J. 2009;105 Spec No:74-77.


In vivo off-resonance saturation magnetic resonance imaging of alphavbeta3-targeted superparamagnetic nanoparticles.
Khemtong C, Kessinger CW, Ren J, Bey EA, Yang SG, Guthi JS, Boothman DA, Sherry AD, Gao J.
Cancer Res. 2009;69(4):1651-1658.

PMC2821739.

Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations.
Konstantinidou G, Bey EA, Rabellino A, Schuster K, Maira MS, Gazdar AF, Amici A, Boothman DA, Scaglioni PP.
Cancer Res. 2009;69(19):7644-7652.

PMC2760010.

Nanoparticle inhalation impairs endothelium-dependent vasodilation in subepicardial arterioles.
LeBlanc AJ, Cumpston JL, Chen BT, Frazer DG, Castranova V, Nurkiewicz TR.
J Toxicol Environ Health A. 2009;72(24):1576-1584.

PMC2808198.

Lung cancer-associated JmjC domain protein mdig suppresses formation of tri-methyl lysine 9 of histone H3.
Lu Y, Chang QS, Zhang Y, Beezhold KJ, Rojanasakul Y, Zhao H, Castranova V, Shi XL, Chen F.
Cell Cycle. 2009;8(13)


An integrative genomic and proteomic approach to chemosensitivity prediction.
Ma Y, Ding ZY, Qian Y, Wan YW, Tosun K, Shi XL, Castranova V, Harner EJ, Guo NL.
Int J Oncol. 2009;34(1):107-115.

PMC2667126.

Oxidative stress and inflammatory response in dermal toxicity of single-walled carbon nanotubes.
Murray AR, Kisin E, Leonard SS, Young SH, Kommineni C, Kagan VE, Castranova V, Shvedova AA.
Toxicology. 2009;257(3):161-171.


Understanding biophysicochemical interactions at the nano-bio interface.
Nel AE, Madler L, Velegol D, Xia T, Hoek EM, Somasundaran P, Klaessig F, Castranova V, Thompson M.
Nat Mater. 2009;8(7):543-557.


Pulmonary nanoparticle exposure disrupts systemic microvascular nitric oxide signaling.
Nurkiewicz TR, Porter DW, Hubbs AF, Stone S, Chen BT, Frazer DG, Boegehold MA, Castranova V.
Toxicol Sci. 2009;110(1):191-203.

PMC2696324.

Safety assessment of azelaic acid and its derivatives entrapped in nanovesicles.
Panyosak A, Manosroi J, Rojanasakul Y, Manosroi A.
Hum Exp Toxicol. 2009;28(6-7):387-392.


The soluble nickel component of residual oil fly ash alters pulmonary host defense in rats.
Roberts JR, Young SH, Castranova V, Antonini JM.
J Immunotoxicol. 2009;6(1):49-61.


Surface area of particle administered versus mass in determining the pulmonary toxicity of ultrafine and fine carbon black: comparison to ultrafine titanium dioxide.
Sager TM, Castranova V.
Part Fibre Toxicol. 2009;6:15

PMC2681444.

Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus?
Shvedova AA, Kisin ER, Porter D, Schulte P, Kagan VE, Fadeel B, Castranova V.
Pharmacol Ther. 2009;121(2):192-204.


A mass balance mercury budget for a mine-dominated lake: Clear Lake, California.
Suchanek TH, Cooke J, Keller K, Jorgensen S, Richerson PJ, Eagles-Smith CA, Harner EJ, Adam DP.
Water Air Soil Poll. 2009;196(1-4):51-73.


Visible light photocatalytic activity in nitrogen-doped TiO2 nanobelts.
Tafen DN, Wang J, Wu NQ, Lewis JP.
Appl Phys Lett. 2009;94(9)


Smoking and breast cancer screening in West Virginia: opportunities for intervention.
Tworek C, Nadpara PA, Adkins B, Horn KA, Dino GA, Christy D, Madhavan SS.
WV Med J. 2009;105 Spec No:48-53.


Origin of photocatalytic activity of nitrogen-doped TiO2 nanobelts.
Wang J, Tafen DN, Lewis JP, Hong ZL, Manivannan A, Zhi MJ, Li M, Wu NQ.
J Am Chem Soc. 2009;131(34):12290-12297.


Electrocatalytic drug metabolism by CYP2C9 bonded to a self-assembled monolayer-modified electrode.
Yang ML, Kabulski JL, Wollenberg L, Chen XQ, Subramanian M, Tracy TS, Lederman D, Gannett PM, Wu NQ.
Drub Metab Dispos. 2009;37(4):892-899.

PMC2680531.

Characterization of an alternatively spliced GADD45alpha, GADD45alpha1 isoform, in arsenic-treated epithelial cells.
Zhang Y, Beezhold KJ, Castranova V, Shi XL, Chen F.
Mol Carcinog. 2009;48(5):454-464.

PMC2680285.

Reactive oxygen species- and nitric oxide-mediated lung inflammation and mitochondrial dysfunction in wild-type and iNOS-deficient mice exposed to diesel exhaust particles.
Zhao HW, Ma JK, Barger MW, Mercer RR, Millecchia LL, Schwegler-Berry D, Castranova V, Ma JY.
J Toxicol Environ Health A. 2009;72(8):560-570.


Metallic nickel nano- and fine particles induce JB6 cell apoptosis through a caspase-8/AIF mediated cytochrome c-independent pathway.
Zhao J, Bowman LL, Zhang X, Shi XL, Jiang BH, Castranova V, Ding M.
J Nanobiotechnology. 2009;7:2

PMC2673202.

Titanium dioxide (TiO2) nanoparticles induce JB6 cell apoptosis through activation of the caspase-8/Bid and mitochondrial pathways.
Zhao J, Bowman LL, Zhang X, Vallyathan V, Young SH, Castranova V, Ding M.
J Toxicol Environ Health A. 2009;72(19):1141-1149.


Occupational toxicology of nickel and nickel compounds.
Zhao J, Shi X, Castranova V, Ding M.
J Environ Pathol Toxicol Oncol. 2009;28(3):177-208.


Evaluating the toxicity of airborne particulate matter and nanoparticles by measuring oxidative stress potential--a workshop report and consensus statement.
Ayres JG, Borm PJ, Cassee FR, Castranova V, Donaldson K, Ghio A, Harrison RM, Hider R, Kelly F, Kooter IM, Marano F, Maynard RL, Mudway I, Nel A, Sioutas C, Smith S, Baeza-Squiban A, Cho A, Duggan S, Froines J.
Inhal Toxicol. 2008;20(1):75-99.


Superoxide-mediated proteasomal degradation of Bcl-2 determines cell susceptibility to Cr(VI)-induced apoptosis.
Azad N, Iyer AK, Manosroi A, Wang LY, Rojanasakul Y.
Carcinogenesis. 2008;29(8):1538-1545.

PMC2516494.

Inflammation and lung cancer: roles of reactive oxygen/nitrogen species.
Azad N, Rojanasakul Y, Vallyathan V.
J Toxicol Environ Health B Crit Rev. 2008;11(1):1-15.


Aerosolization of single-walled carbon nanotubes for an inhalation study.
Baron PA, Deye GJ, Chen BT, Schwegler-Berry DE, Shvedova AA, Castranova V.
Inhal Toxicol. 2008;20(8):751-760.


Effects of coal syngas impurities on anodes of solid oxide fuel cells.
Cayan FN, Zhi MJ, Pakalapati SR, Celik I, Wu NQ, Gemmen R.
J Power Sources. 2008;185(2):595-602.


Tumor promoting or tumor suppressing of NF-kappa B, a matter of cell context dependency.
Chen F, Beezhold KJ, Castranova V.
Int Rev Immunol. 2008;27(4):183-204.


Cost-effectiveness analysis of the not on tobacco program for adolescent smoking cessation.
Dino GA, Horn KA, Abdulkadri A, Kalsekar ID, Branstetter SA.
Prev Sci. 2008;9(1):38-46.


Confirmation of gene expression-based prediction of survival in non-small cell lung cancer.
Guo NL, Wan YW, Tosun K, Lin H, Msiska Z, Flynn DC, Remick SC, Vallyathan V, Dowlati A, Shi XL, Castranova V, Beer DG, Qian Y.
Clin Cancer Res. 2008;14(24):8213-8220.

PMC2605664.

Feasibility of a smoking cessation intervention for teens in the emergency department: reach, implementation fidelity, and acceptability.
Horn KA, Dino GA, Hamilton C, Noerachmanto N, Zhang J.
Am J Crit Care. 2008;17(3):205-216.


A profile of teen smokers who volunteered to participate in school-based smoking intervention.
Horn KA, Dino GA, Branstetter SA, Zhang J, Kelley G, Noerachmanto N, Tworek C.
Tob Induc Dis. 2008;4:6

PMC2556032.

Applying community-based participatory research principles to the development of a smoking-cessation program for American Indian teens: "Telling Our Story".
Horn KA, McCracken L, Dino GA, Brayboy M.
Health Educ Behav. 2008;35(1):44-69.


Respiratory toxicologic pathology of inhaled diacetyl in sprague-dawley rats.
Hubbs AF, Goldsmith WT, Kashon ML, Frazer DG, Mercer RR, Battelli LA, Kullman GJ, Schwegler-Berry D, Friend S, Castranova V.
Toxicol Pathol. 2008;36(2):330-344.


Re: Induction of mesothelioma in p53+/- mouse by intraperitoneal application of multi-wall carbon nanotube.
Ichihara G, Castranova V, Tanioka A, Miyazawa K.
J Toxicol Sci. 2008;33(3):381-382.


Role of S-nitrosylation in apoptosis resistance and carcinogenesis.
Iyer AK, Azad N, Wang LY, Rojanasakul Y.
Nitric Oxide. 2008;19(2):146-151.

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Up- and down-conversion cubic zirconia and Hafnia nanobelts.
Jiang CL, Wang F, Wu NQ, Liu XG.
Advanced Materials. 2008;20(24):4826-+.


Three-dimensional localization and quantification of PAF-induced gap formation in intact venular microvessels.
Jiang Y, Wen K, Zhou XD, Schwegler-Berry D, Castranova V, He P.
Am J Physiol Heart Circ Physiol. 2008;295(2):H898-H906.

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Comparison of the biological activity between ultrafine and fine titanium dioxide particles in RAW 264.7 cells associated with oxidative stress.
Kang JL, Moon C, Lee HS, Lee HW, Park EM, Kim HS, Castranova V.
J Toxicol Environ Health A. 2008;71(8):478-485.


Mortality associated with a bark beetle outbreak in dwarf mistletoe-infested ponderosa pine stands in Arizona.
Kenaley S, Mathiasen R, Harner EJ.
West J Appl For. 2008;23(2):113-120.


Modulating temporal control of NF-kappaB activation: implications for therapeutic and assay selection.
Klinke DJ, Ustyugova IV, Brundage KM, Barnett JB.
Biophys J. 2008;94(11):4249-4259.

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Dependence of reactive oxygen species and FLICE inhibitory protein on lipofectamine-induced apoptosis in human lung epithelial cells.
Kongkaneramit L, Sarisuta N, Azad N, Lu YZ, Iyer AK, Wang LY, Rojanasakul Y.
J Pharmacol Exp Ther. 2008;325(3):969-977.


3,4-Dichloropropionanilide (DCPA) inhibits T-cell activation by altering the intracellular calcium concentration following store depletion.
Lewis TL, Brundage KM, Brundage RA, Barnett JB.
Toxicol Sci. 2008;103(1):97-107.


A large-area nanoscale gold hemisphere pattern as a nanoelectrode array.
Li HQ, Wu NQ.
Nanotechnology. 2008;19(27):275301


Large-area well-ordered nanodot array pattern fabricated with self-assembled nanosphere template.
Li HQ, Low J, Brown KS, Wu NQ.
IEEE Sensors Journal. 2008;8(5-6):880-884.


Human papillomavirus type 16 reduces the expression of microRNA-218 in cervical carcinoma cells.
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Oncogene. 2008;27(18):2575-2582.

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Alteration of deposition pattern and pulmonary response as a result of improved dispersion of aspirated single-walled carbon nanotubes in a mouse model.
Mercer RR, Scabilloni J, Wang LY, Kisin E, Murray AR, Schwegler-Berry D, Shvedova AA, Castranova V.
Am J Physiol Lung Cell Mol Physiol. 2008;294(1):L87-L97.


Factors related to depressed mood in adults with chronic obstructive pulmonary disease after hospitalization.
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Home Healthc Nurse. 2008;26(8):474-482.

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Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction.
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Raw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappaB, and Akt in normal and malignant human mesothelial cells.
Pacurari M, Yin XJ, Zhao J, Ding M, Leonard SS, Schwegler-Berry D, Ducatman BS, Sbarra D, Hoover MD, Castranova V, Vallyathan V.
Environ Health Perspect. 2008;116(9):1211-1217.

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In vitro nephrotoxicity induced by propanil.
Rankin GO, Racine C, Sweeney A, Kraynie A, Anestis DK, Barnett JB.
Environ Toxicol. 2008;23(4):435-442.


Developmental immunotoxicity of atrazine in rodents.
Rowe AM, Brundage KM, Barnett JB.
Basic Clin Pharmacol Toxicol. 2008;102(2):139-145.


Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area.
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A review of the immunotoxicity of the pesticide 3,4-dichloropropionanalide.
Salazar KD, Ustyugova IV, Brundage KM, Barnett JB, Schafer R.
J Toxicol Environ Health B Crit Rev. 2008;11(8):630-645.


Haplotype inference and block partitioning in mixed population samples.
Sazonova N, Harner EJ.
J Bioinform Comput Biol. 2008;6(6):1177-1192.


Pharmacologic effects of grain weevil extract on isolated guinea pig tracheal smooth muscle.
Schachter EN, Zuskin E, Arumugam U, Goswami S, Castranova V, Whitmer M, Chiarelli A.
Lung. 2008;186(5):317-321.


Sharpening the focus on occupational safety and health in nanotechnology.
Schulte PA, Geraci C, Zumwalde RD, Hoover M, Castranova V, Kuempel E, Murashov V, Vainio H, Savolainen K.
Scand J Work Environ Health. 2008;34(6):471-478.


Options for occupational health surveillance of workers potentially exposed to engineered nanoparticles: state of the science.
Schulte PA, Trout D, Zumwalde RD, Kuempel E, Geraci CL, Castranova V, Mundt DJ, Mundt KA, Halperin WE.
J Occup Environ Med. 2008;50(5):517-526.


Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis.
Shvedova AA, Kisin E, Murray AR, Johnson VJ, Gorelik O, Arepalli S, Hubbs AF, Mercer RR, Keohavong P, Sussman N, Jin J, Yin J, Stone S, Chen BT, Deye G, Maynard A, Castranova V, Baron PA, Kagan VE.
Am J Physiol Lung Cell Mol Physiol. 2008;295(4):L552-L565.

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Sequential exposure to carbon nanotubes and bacteria enhances pulmonary inflammation and infectivity.
Shvedova AA, Fabisiak JP, Kisin ER, Murray AR, Roberts JR, Tyurina YY, Antonini JM, Feng WH, Kommineni C, Reynolds J, Barchowsky A, Castranova V, Kagan VE.
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Increased accumulation of neutrophils and decreased fibrosis in the lung of NADPH oxidase-deficient C57BL/6 mice exposed to carbon nanotubes.
Shvedova AA, Kisin ER, Murray AR, Kommineni C, Castranova V, Fadeel B, Kagan VE.
Toxicol Appl Pharmacol. 2008;231(2):235-240.


Mercury in abiotic matrices of Clear Lake, California: human health and ecotoxicological implications.
Suchanek TH, Eagles-Smith CA, Slotton DG, Harner EJ, Adam DP.
Ecol Appl. 2008;18(8 Suppl):A128-A157.


Spatiotemporal trends in fish mercury from a mine-dominated ecosystem: Clear Lake, California.
Suchanek TH, Eagles-Smith CA, Slotton DG, Harner EJ, Colwell AE, Anderson NL, Mullen LH, Flanders JR, Adam DP, McElroy KJ.
Ecol Appl. 2008;18(8 Suppl):A177-A195.


The legacy of mercury cycling from mining sources in an aquatic ecosystem: from ore to organism.
Suchanek TH, Richerson PJ, Zierenberg RA, Eagles-Smith CA, Slotton DG, Harner EJ, Osleger DA, Anderson DW, Cech JJ, Jr., Schladow SG, Colwell AE, Mount JF, King PS, Adam DP, McElroy KJ.
Ecol Appl. 2008;18(8 Suppl):A12-A28.


Mine-derived mercury: effects on lower trophic species in Clear Lake, California.
Suchanek TH, Eagles-Smith CA, Slotton DG, Harner EJ, Adam DP, Colwell AE, Anderson NL, Woodward DL.
Ecol Appl. 2008;18(8 Suppl):A158-A176.


Is Clear Lake methylmercury distribution decoupled from bulk mercury loading?
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Ecol Appl. 2008;18(8 Suppl):A107-A127.


The application of molecular modeling for prediction of substrate specificity in cytochrome P450 1A2 mutants.
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Sol-gel derived La0.6Sr0.4CoO3 nanoparticles, nanotubes, nanowires and thin films.
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Thin Solid Films. 2008;517(2):582-587.


G-CSF stimulates Jak2-dependent Gab2 phosphorylation leading to Erk1/2 activation and cell proliferation.
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Cell Signal. 2008;20(10):1890-1899.

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Peroxide is a key mediator of Bcl-2 down-regulation and apoptosis induction by cisplatin in human lung cancer cells.
Wang LY, Chanvorachote P, Toledo D, Stehlik C, Mercer RR, Castranova V, Rojanasakul Y.
Mol Pharmacol. 2008;73(1):119-127.


The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation.
Wang LY, Azad N, Kongkaneramit L, Chen F, Lu YJ, Jiang BH, Rojanasakul Y.
J Immunol. 2008;180(5):3072-3080.

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A lactate electrochemical biosensor with a titanate nanotube as direct electron transfer promoter.
Yang ML, Wang J, Li HQ, Zheng JG, Wu NQ.
Nanotechnology. 2008;19(7)


Oxidative stress and chromium(VI) carcinogenesis.
Yao H, Guo NL, Jiang BH, Luo J, Shi XL.
J Environ Pathol Toxicol Oncol. 2008;27(2):77-88.


Electrochemical and microstructural analysis of nickel-yttria-stabilized zirconia electrode operated in phosphorus-containing syngas.
Zhi MJ, Chen XQ, Finklea H, Celik I, Wu NQ.
J Power Sources. 2008;183(2):485-490.


Nonhomologous end joining is essential for cellular resistance to the novel antitumor agent, beta-lapachone.
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Cancer Res. 2007;67(14):6936-6945.


An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone.
Bey EA, Bentle MS, Reinicke KE, Dong Y, Yang CR, Girard L, Minna JD, Bornmann WG, Gao J, Boothman DA.
Proc Natl Acad Sci USA. 2007;104(28):11832-11837.

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Beta-lapachone-containing PEG-PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells.
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J Control Release. 2007;122(3):365-374.

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Incorporation of an internal ribosome entry site-dependent mechanism in arsenic-induced GADD45 alpha expression.
Chang QS, Bhatia D, Zhang Y, Meighan T, Castranova V, Shi XL, Chen F.
Cancer Res. 2007;67(13):6146-6154.


Nuclear factor-kappaB, an unappreciated tumor suppressor.
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Cancer Res. 2007;67(23):11093-11098.


Cellular motors for molecular manufacturing.
Dinu CZ, Chrisey DB, Diez S, Howard J.
Anat Rec (Hoboken). 2007;290(10):1203-1212.


Printing technologies for fabrication of bioactive and regular microarrays of streptavidin.
Dinu CZ, Dinca V, Howard J, Chrisey DB.
Applied Surface Science. 2007;253(19):8119-8124.


Monitoring nitinol alloy surface reactions for biofouling studies.
Dinu CZ, Dinca VC, Soare S, Moldovan A, Smarandache D, Scarisoareanu N, Barbalat A, Birjega R, Dinescu M, DiStefano VF.
Appl Surf Sci. 2007;253(19):7719-7723.


Matrix-assisted pulsed-laser evaporation of DOPA-modified poly(ethylene glycol) thin films.
Doraiswamy A, Dinu CZ, Cristescu R, Messersmith PB, Chisholm BJ, Stafslien SJ, Chrisey DB, NarayaN' RJ.
J Adhes Sci Technol. 2007;21(3-4):287-299.


Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation.
Dorfleutner A, Bryan NB, Talbott SJ, Funya KN, Rellick SL, Reed JC, Shi XL, Rojanasakul Y, Flynn DC, Stehlik C.
Infect Immun. 2007;75(3):1484-1492.

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A Shope fibroma virus PYRIN-only protein modulates the host immune response.
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Virus Genes. 2007;35(3):685-694.


School-based programs: lessons learned from CATCH, Planet Health, and Not-On-Tobacco.
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Prev Chronic Dis. 2007;4(2):A33

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Individualized survival and treatment response predictions for breast cancers using phospho-EGFR, phospho-ER, phospho-HER2/neu, phospho-IGF-IR/In, phospho-MAPK, and phospho-p70S6K proteins.
Guo NL, Abraham J, Flynn DC, Castranova V, Shi XL, Qian Y.
Int J Biol Markers. 2007;22(1):1-11.


Efficacy of an emergency department-based motivational teenage smoking intervention.
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Adsorption and desorption of stearic acid self-assembled monolayers on aluminum oxide.
Lim MS, Feng K, Chen X, Wu NQ, Raman A, Nightingale J, Gawalt ES, Korakakis D, Hornak LA, Timperman AT.
Langmuir. 2007;23(5):2444-2452.


Population-based molecular prognosis of breast cancer by transcriptional profiling.
Ma Y, Qian Y, Wei L, Abraham J, Shi XL, Castranova V, Harner EJ, Flynn DC, Guo NL.
Clin Cancer Res. 2007;13(7):2014-2022.


Characteristics and anti-proliferative activity of azelaic acid and its derivatives entrapped in bilayer vesicles in cancer cell lines.
Manosroi A, Panyosak A, Rojanasakul Y, Manosroi J.
J Drug Target. 2007;15(5):334-341.


Identification of differentially expressed genes in HPV-positive and HPV-negative oropharyngeal squamous cell carcinomas.
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Eur J Cancer. 2007;43(2):415-432.

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Pulmonary toxicity of Expancel microspheres in the rat.
Porter DW, Hubbs AF, Baron PA, Millecchia LL, Wolfarth MG, Battelli LA, Schwegler-Berry DE, Beighley CM, Andrew ME, Castranova V.
Toxicol Pathol. 2007;35(5):702-714.


In vitro atrazine-exposure inhibits human natural killer cell lytic granule release.
Rowe AM, Brundage KM, Barnett JB.
Toxicol Appl Pharmacol. 2007;221(2):179-188.

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Identification of a novel domain at the N terminus of caveolin-1 that controls rear polarization of the protein and caveolae formation.
Sun XH, Flynn DC, Castranova V, Millecchia LL, Beardsley AR, Liu J.
J Biol Chem. 2007;282(10):7232-7241.


3,4-dichloropropionaniline suppresses normal macrophage function.
Ustyugova IV, Frost LL, Van Dyke K, Brundage KM, Schafer R, Barnett JB.
Toxicol Sci. 2007;97(2):364-374.


Ph+/VE-cadherin+ identifies a stem cell like population of acute lymphoblastic leukemia sustained by bone marrow niche cells.
Wang L, O'Leary HA, Fortney JE, Gibson LF.
Blood. 2007;110(9):3334-3344.

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Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor.
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Cancer Res. 2007;67(22):10823-10830.


Anion bridged nanosheet from self-assembled G-quadruplexes.
Zhong C, Wang J, Wu NQ, Wu G, Zavalij PY, Shi XD.
Chem Commun (Camb). 2007;(30):3148-3150.


Vaccine delivery--current trends and future.
Azad N, Rojanasakul Y.
Curr Drug Deliv. 2006;3(2):137-146.


S-nitrosylation of Bcl-2 inhibits its ubiquitin-proteasomal degradation. A novel antiapoptotic mechanism that suppresses apoptosis.
Azad N, Vallyathan V, Wang LY, Tantishaiyakul V, Stehlik C, Leonard SS, Rojanasakul Y.
J Biol Chem. 2006;281(45):34124-34134.


Calcium-dependent modulation of poly(ADP-ribose) polymerase-1 alters cellular metabolism and DNA repair.
Bentle MS, Reinicke KE, Bey EA, Spitz DR, Boothman DA.
J Biol Chem. 2006;281(44):33684-33696.


New tricks for old drugs: the anticarcinogenic potential of DNA repair inhibitors.
Bentle MS, Bey EA, Dong Y, Reinicke KE, Boothman DA.
J Mol Histol. 2006;37(5-7):203-218.


Mornings with Art, lessons learned: feedback regulation, restriction threshold biology, and redundancy govern molecular stress responses.
Bey EA, Wuerzberger-Davis SM, Pink JJ, Yang CR, Araki S, Reinicke KE, Bentle MS, Dong Y, Cataldo E, Criswell TL, Wagner MW, Li L, Gao J, Boothman DA.
J Cell Physiol. 2006;209(3):604-610.


Nitric oxide regulates cell sensitivity to cisplatin-induced apoptosis through S-nitrosylation and inhibition of Bcl-2 ubiquitination.
Chanvorachote P, Nimmannit U, Stehlik C, Wang LY, Jiang BH, Ongpipatanakul B, Rojanasakul Y.
Cancer Res. 2006;66(12):6353-6360.


Finding NEMO by K63-linked polyubiquitin chain.
Chen F, Bhatia D, Chang QS, Castranova V.
Cell Death Differ. 2006;13(11):1835-1838.


Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells.
Chen F, Lu Y, Castranova V, Li Z, Karin M.
J Biol Chem. 2006;281(48):37142-37149.


Factors related to chronic obstructive pulmonary disease readmission in Taiwan.
Chen YJ, Narsavage GL.
West J Nurs Res. 2006;28(1):105-124.


Nickel-titanium alloy: cytotoxicity evaluation on microorganism culture.
Dinca VC, Soare S, Barbalat A, Dinu CZ, Moldovan A, Stoica I, Vassu T, Purice A, Scarisoareanu N, Birjega R, Craciun V, DeStefano VF, Dinescu M.
Applied Surface Science. 2006;252(13):4619-4624.


Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathway.
Ding M, Huang C, Lu Y, Bowman LL, Castranova V, Vallyathan V.
Am J Physiol Lung Cell Mol Physiol. 2006;290(2):L291-L297.


Cyanidin-3-glucoside, a natural product derived from blackberry, exhibits chemopreventive and chemotherapeutic activity.
Ding M, Feng R, Wang SY, Bowman LL, Lu Y, Qian Y, Castranova V, Jiang BH, Shi XL.
J Biol Chem. 2006;281(25):17359-17368.


Parallel manipulation of bifunctional DNA molecules on structured surfaces using kinesin-driven microtubules.
Dinu CZ, Opitz J, Pompe W, Howard J, Mertig M, Diez S.
Small. 2006;2(8-9):1090-1098.


Constructing molecular classifiers for the accurate prognosis of lung adenocarcinoma.
Guo NL, Ma Y, Ward R, Castranova V, Shi XL, Qian Y.
Clin Cancer Res. 2006;12(11 Pt 1):3344-3354.


A novel role for 3, 4-dichloropropionanilide (DCPA) in the inhibition of prostate cancer cell migration, proliferation, and hypoxia-inducible factor 1alpha expression.
Jiang BH, Liu LZ, Schafer R, Flynn DC, Barnett JB.
BMC Cancer. 2006;6:204

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Shape-controlled growth of micrometer-sized gold crystals by a slow reduction method.
Liu XG, Wu NQ, Wunsch BH, Barsotti RJ, Stellacci F.
Small. 2006;2(8-9):1046-1050.


Phosphatidylinositol 3-kinase/Akt positively regulates Fas (CD95)-mediated apoptosis in epidermal Cl41 cells.
Lu B, Wang LY, Stehlik C, Medan D, Huang C, Hu S, Chen F, Shi XL, Rojanasakul Y.
J Immunol. 2006;176(11):6785-6793.


Predicting cancer drug response by proteomic profiling.
Ma Y, Ding Z, Qian Y, Shi XL, Castranova V, Harner EJ, Guo NL.
Clin Cancer Res. 2006;12(15):4583-4589.


Role of PI3K and AKT specific isoforms in ovarian cancer cell migration, invasion and proliferation through the p70S6K1 pathway.
Meng Q, Xia C, Fang J, Rojanasakul Y, Jiang BH.
Cell Signal. 2006;18(12):2262-2271.


Reactive oxygen species mediate caspase activation and apoptosis induced by lipoic acid in human lung epithelial cancer cells through Bcl-2 down-regulation.
Moungjaroen J, Nimmannit U, Callery PS, Wang LY, Azad N, Lipipun V, Chanvorachote P, Rojanasakul Y.
J Pharmacol Exp Ther. 2006;319(3):1062-1069.


Multifunctional polymeric micelles as cancer-targeted, MRI-ultrasensitive drug delivery systems.
Nasongkla N, Bey EA, Ren J, Ai H, Khemtong C, Guthi JS, Chin SF, Sherry AD, Boothman DA, Gao J.
Nano Lett. 2006;6(11):2427-2430.


Systemic microvascular dysfunction and inflammation after pulmonary particulate matter exposure.
Nurkiewicz TR, Porter DW, Barger MW, Millecchia LL, Rao KM, Marvar PJ, Hubbs AF, Castranova V, Boegehold MA.
Environ Health Perspect. 2006;114(3):412-419.

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Nitric oxide and reactive oxygen species production causes progressive damage in rats after cessation of silica inhalation.
Porter DW, Millecchia LL, Willard P, Robinson VA, Ramsey D, McLaurin J, Khan A, Brumbaugh K, Beighley CM, Teass A, Castranova V.
Toxicol Sci. 2006;90(1):188-197.


Immunomodulatory effects of maternal atrazine exposure on male Balb/c mice.
Rowe AM, Brundage KM, Schafer R, Barnett JB.
Toxicol Appl Pharmacol. 2006;214(1):69-77.

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Evidence for a novel endocrine disruptor: the pesticide propanil requires the ovaries and steroid synthesis to enhance humoral immunity.
Salazar KD, Miller MR, Barnett JB, Schafer R.
Toxicol Sci. 2006;93(1):62-74.


Propanil exposure induces delayed but sustained abrogation of cell-mediated immunity through direct interference with cytotoxic T-lymphocyte effectors.
Sheil JM, Frankenberry MA, Schell TD, Brundage KM, Barnett JB.
Environ Health Perspect. 2006;114(7):1059-1064.

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Welding fume exposure and associated inflammatory and hyperplastic changes in the lungs of tumor susceptible a/j mice.
Solano-Lopez C, Zeidler-Erdely PC, Hubbs AF, Reynolds SH, Roberts JR, Taylor MD, Young SH, Castranova V, Antonini JM.
Toxicol Pathol. 2006;34(4):364-372.


Stable aqueous dispersions of graphitic nanoplatelets via the reduction of exfoliated graphite oxide in the presence of poly(sodium 4-styrenesulfonate).
Stankovich S, Piner RD, Chen XQ, Wu NQ, Nguyen ST, Ruoff RS.
J Mater Chem. 2006;16(2):155-158.


Predictors of health promotion behavior in women without prior history of coronary heart disease.
Thanavaro JL, Moore SM, Anthony MK, Narsavage GL, Delicath T.
Appl Nurs Res. 2006;19(3):149-155.


Predictors of poor coronary heart disease knowledge level in women without prior coronary heart disease.
Thanavaro JL, Moore SM, Anthony MK, Narsavage GL, Delicath T.
J Am Acad Nurse Pract. 2006;18(12):574-581.


Induction of secondary apoptosis, inflammation, and lung fibrosis after intratracheal instillation of apoptotic cells in rats.
Wang LY, Scabilloni JF, Antonini JM, Rojanasakul Y, Castranova V, Mercer RR.
Am J Physiol Lung Cell Mol Physiol. 2006;290(4):L695-L702.


Role of lung surfactant in phagocytic clearance of apoptotic cells by macrophages in rats.
Wang LY, Scabilloni JF, Antonini JM, Castranova V, Rojanasakul Y, Roberts JR, Zhang Z, Mercer RR.
Lab Invest. 2006;86(5):458-466.


Impedance characterization of ZnO nanobelt/Pd Schottky contacts in ammonia.
Xu JH, Wu NQ, Jiang CB, Zhao MH, Li J, Wei YG, Mao SX.
Small. 2006;2(12):1458-1461.


Impedance characterization of ZnO nanobett/Pd Schottky contacts in ammonia.
Xu JH, Wu NQ, Jiang CB, Zhao MH, Li J, Wei YG, Mao SX.
Small. 2006;2(12):1458-1461.


Nucleolin links to arsenic-induced stabilization of GADD45alpha mRNA.
Zhang Y, Bhatia D, Xia H, Castranova V, Shi X, Chen F.
Nucleic Acids Res. 2006;34(2):485-495.

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Loss of caveolin-1 polarity impedes endothelial cell polarization and directional movement.
Beardsley AR, Fang K, Mertz H, Castranova V, Friend S, Liu J.
J Biol Chem. 2005;280(5):3541-3547.


Nitric oxide negatively regulates Fas CD95-induced apoptosis through inhibition of ubiquitin-proteasome-mediated degradation of FLICE inhibitory protein.
Chanvorachote P, Nimmannit U, Wang LY, Stehlik C, Lu B, Azad N, Rojanasakul Y.
J Biol Chem. 2005;280(51):42044-42050.


Effect of N-2 flow rate on morphology and structure of ZnO nanocrystals synthesized via vapor deposition.
Chen Z, Wu NQ, Shan ZW, Zhao MH, Li SX, Jiang CB, Chyu MK, Mao SX.
Scripta Materialia. 2005;52(1):63-67.


Characterization of thymic atrophy and the mechanism of thymocyte depletion after in vivo exposure to a mixture of herbicides.
de la Rosa P, Barnett JB, Schafer R.
J Toxicol Environ Health A. 2005;68(2):81-98.


Facile scheme for fabricating solid-state nanostructures using e-beam lithography and solution precursors.
Donthu SK, Pan Z, Myers B, Shekhawat G, Wu NQ, Dravid VP.
Nano Lett. 2005;5(9):1710-1715.


Regiospecificity of human cytochrome P450 1A1-mediated oxidations: the role of steric effects.
Ericksen SS, Szklarz GD.
J Biomol Struct Dyn. 2005;23(3):243-256.


Inhibition of activator protein-1, NF-kappaB, and MAPKs and induction of phase 2 detoxifying enzyme activity by chlorogenic acid.
Feng R, Lu Y, Bowman LL, Qian Y, Castranova V, Ding M.
J Biol Chem. 2005;280(30):27888-27895.


Human papillomavirus-16 associated squamous cell carcinoma of the head and neck (SCCHN): a natural disease model provides insights into viral carcinogenesis.
Ferris RL, Martinez I, Sirianni N, Wang J, Lopez-Albaitero A, Gollin SM, Johnson JT, Khan S.
Eur J Cancer. 2005;41(5):807-815.


Direct evidence of oxidized gold on supported gold catalysts.
Fu L, Wu NQ, Yang JH, Qu F, Johnson DL, Kung MC, Kung HH, Dravid VP.
J Phys Chem B. 2005;109(9):3704-3706.


Correlates of oxidative stress and free-radical activity in serum from asymptomatic shipyard welders.
Han SG, Kim Y, Kashon ML, Pack DL, Castranova V, Vallyathan V.
Am J Respir Crit Care Med. 2005;172(12):1541-1548.


Quit and reduction rates for a pilot study of the American Indian Not On Tobacco (N-O-T) program.
Horn KA, McGloin T, Dino GA, Manzo K, McCracken L, Shorty L, Lowry-Chavis L, Noerachmanto N.
Prev Chronic Dis. 2005;2(4):A13

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Regulation of Fas (CD95)-induced apoptotic and necrotic cell death by reactive oxygen species in macrophages.
Medan D, Wang LY, Toledo D, Lu B, Stehlik C, Jiang BH, Shi XL, Rojanasakul Y.
J Cell Physiol. 2005;203(1):78-84.


Statement on home care for patients with respiratory disorders.
Narsavage GL, Anderson K, Roksoky J, et.al.
Am J Respir Crit Care Med. 2005;171(12):1443-1464.


Efficacy of beta-lapachone in pancreatic cancer treatment: exploiting the novel, therapeutic target NQO1.
Ough M, Lewis A, Bey EA, Gao J, Ritchie JM, Bornmann WG, Boothman DA, Oberley LW, Cullen JJ.
Cancer Biol Ther. 2005;4(1):95-102.


Susceptibility of cancer cells to beta-lapachone is enhanced by ionizing radiation.
Park HJ, Ahn KJ, Ahn SD, Choi E, Lee SW, Williams B, Kim EJ, Griffin R, Bey EA, Bornmann WG, Gao J, Park HJ, Boothman DA, Song CW.
Int J Radiat Oncol Biol Phys. 2005;61(1):212-219.


Cdc42 regulates arsenic-induced NADPH oxidase activation and cell migration through actin filament reorganization.
Qian Y, Liu KJ, Chen Y, Flynn DC, Castranova V, Shi XL.
J Biol Chem. 2005;280(5):3875-3884.


Management of community-acquired pneumonia in the home: an American College of Chest Physicians clinical position statement.
Ramsdell J, Narsavage GL, Fink JB.
Chest. 2005;127(5):1752-1763.


Development of beta-lapachone prodrugs for therapy against human cancer cells with elevated NAD(P)H:quinone oxidoreductase 1 levels.
Reinicke KE, Bey EA, Bentle MS, Pink JJ, Ingalls ST, Hoppel CL, Misico RI, Arzac GM, Burton G, Bornmann WG, Sutton D, Gao J, Boothman DA.
Clin Cancer Res. 2005;11(8):3055-3064.


The polysaccharide antibody response after Streptococcus pneumoniae vaccination is differentially enhanced or suppressed by 3,4-dichloropropionanilide and 2,4-dichlorophenoxyacetic acid.
Salazar KD, de la Rosa P, Barnett JB, Schafer R.
Toxicol Sci. 2005;87(1):123-133.


Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice.
Shvedova AA, Kisin ER, Mercer R, Murray AR, Johnson VJ, Potapovich AI, Tyurina YY, Gorelik O, Arepalli S, Schwegler-Berry D, Hubbs AF, Antonini JM, Evans DE, Ku BK, Ramsey D, Maynard A, Kagan VE, Castranova V, Baron PA.
Am J Physiol Lung Cell Mol Physiol. 2005;289(5):L698-L708.


VEGF-induced survival of chronic lymphocytic leukemia is independent of Bcl-2 phosphorylation.
Wang L, Coad JE, Fortney JM, Gibson LF.
Leukemia. 2005;19(8):1486-1487.


Activation of transforming growth factor-beta1/p38/Smad3 signaling in stromal cells requires reactive oxygen species-mediated MMP-2 activity during bone marrow damage.
Wang L, Clutter SD, Benincosa J, Fortney JE, Gibson LF.
Stem Cells. 2005;23(8):1122-1134.


VEGF-induced phosphorylation of Bcl-2 influences B lineage leukemic cell response to apoptotic stimuli.
Wang L, Chen L, Benincosa J, Fortney JE, Gibson LF.
Leukemia. 2005;19(3):344-353.


Essential role of p53 in silica-induced apoptosis.
Wang LY, Bowman LL, Lu Y, Rojanasakul Y, Mercer RR, Castranova V, Ding M.
Am J Physiol Lung Cell Mol Physiol. 2005;288(3):L488-L496.


Experimental and computational studies of epithelial transport of mefenamic acid ester prodrugs.
Wiwattanawongsa K, Tantishaiyakul V, Lomlim L, Rojanasakul Y, Pinsuwan S, Keawnopparat S.
Pharm Res. 2005;22(5):721-727.


Impedance-metric Pt/YSZ/Au-Ga2O3 sensor for CO detection at high temperature.
Wu NQ, Chen Z, Xu JH, Chyu MK, Mao SX.
Sensor Actuat B-Chem. 2005;110(1):49-53.


Porous CuO-ZnO nanocomposite for sensing electrode of high-temperature CO solid-state electrochemical sensor.
Wu NQ, Zhao MH, Zheng JG, Jiang CB, Myers B, Li SX, Chyu MK, Mao SX.
Nanotechnology. 2005;16(12):2878-2881.


Hot corrosion mechanism of composite alumina/yttria-stabilized zirconia coating in molten sulfate-vanadate salt.
Wu NQ, Chen Z, Mao SX.
J Am Ceram Soc. 2005;88(3):675-682.


The Human mineral dust-induced gene, mdig, is a cell growth regulating gene associated with lung cancer.
Zhang Y, Lu Y, Yuan BZ, Castranova V, Shi XL, Stauffer JL, Demers LM, Chen F.
Oncogene. 2005;24(31):4873-4882.


Deficiency in Ikkbeta gene enhances arsenic-induced gadd45alpha expression.
Zhang Y, Lu Y, Ding M, Castranova V, Shi XL, Chen F.
Mol Cell Biochem. 2005;279(1-2):163-168.


Transport of organic solutes through amorphous teflon AF films.
Zhao H, Zhang J, Wu NQ, Zhang X, Crowley K, Weber SG.
J Am Chem Soc. 2005;127(43):15112-15119.


fMLP-stimulated neutrophils increase endothelial [Ca2+]i and microvessel permeability in the absence of adhesion: role of reactive oxygen species.
Zhu L, Castranova V, He P.
Am J Physiol Heart Circ Physiol. 2005;288(3):H1331-H1338.


Etoposide differentially affects bone marrow and dermal derived endothelial cells.
Adams SW, Wang L, Fortney JE, Gibson LF.
J Cell Mol Med. 2004;8(3):338-348.


Protein kinase C delta is required for p47phox phosphorylation and translocation in activated human monocytes.
Bey EA, Xu B, Bhattacharjee A, Oldfield CM, Zhao X, Li Q, Subbulakshmi V, Feldman GM, Wientjes FB, Cathcart MK.
J Immunol. 2004;173(9):5730-5738.


Antibiotics and HIV. Healing infection without hindering HAART.
Briggs JM, Narsavage GL.
Adv Nurse Pract. 2004;12(7):26-34.


Altered AP-1 (activating protein-1) activity and c-jun activation in T cells exposed to the amide class herbicide 3,4-dichloropropionanilide (DCPA).
Brundage KM, Schafer R, Barnett JB.
Toxicol Sci. 2004;79(1):98-105.


Orientation of phenacetin and acetaminophen within the active site of human cytochrome P450 1A1 and 1A2.
Deshmukh RS, Ericksen SS, Gannett PM, Szklarz GD.
Drug Metab Rev. 2004;36:68-68.


Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract.
Ding M, Lu Y, Bowman LL, Huang C, Leonard SS, Wang LY, Vallyathan V, Castranova V, Shi XL.
J Biol Chem. 2004;279(11):10670-10676.


Stage of change and smoking cessation outcomes among adolescents.
Dino GA, Kamal KM, Horn KA, Kalsekar ID, Fernandes AW.
Addict Behav. 2004;29(5):935-940.


Blackberry extracts inhibit activating protein 1 activation and cell transformation by perturbing the mitogenic signaling pathway.
Feng R, Bowman LL, Lu Y, Leonard SS, Shi XL, Jiang BH, Castranova V, Vallyathan V, Ding M.
Nutr Cancer. 2004;50(1):80-89.


Respirable coal dust particles modify cytochrome P4501A1 (CYP1A1) expression in rat alveolar cells.
Ghanem MM, Porter DW, Battelli LA, Vallyathan V, Kashon ML, Ma JY, Barger MW, Nath J, Castranova V, Hubbs AF.
Am J Respir Cell Mol Biol. 2004;31(2):171-183.


Stromal cells expressing elevated VCAM-1 enhance survival of B lineage tumor cells.
Hall BM, Fortney JE, Taylor L, Wood H, Wang L, Adams SW, Davis S, Gibson LF.
Cancer Lett. 2004;207(2):229-239.


Exploring the relationship between mental health and smoking cessation: a study of rural teens.
Horn KA, Dino GA, Kalsekar ID, Massey CJ, Manzo-Tennant K, McGloin T.
Prev Sci. 2004;5(2):113-126.


Appalachian teen smokers: not on tobacco 15 months later.
Horn KA, Dino GA, Kalsekar ID, Fernandes AW.
Am J Public Health. 2004;94(2):181-184.

PMC1448225.

The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism.
Liu J, Ericksen SS, Sivaneri M, Besspiata D, Fisher CW, Szklarz GD.
Arch Biochem Biophys. 2004;424(1):33-43.


Particulate matter exposure impairs systemic microvascular endothelium-dependent dilation.
Nurkiewicz TR, Porter DW, Barger MW, Castranova V, Boegehold MA.
Environ Health Perspect. 2004;112(13):1299-1306.

PMC1247520.

Progression of lung inflammation and damage in rats after cessation of silica inhalation.
Porter DW, Hubbs AF, Mercer R, Robinson VA, Ramsey D, McLaurin J, Khan A, Battelli LA, Brumbaugh K, Teass A, Castranova V.
Toxicol Sci. 2004;79(2):370-380.


One breath at a time: living with cystic fibrosis.
Rinaldi CD, Narsavage GL.
J Pediatr Nurs. 2004;19(1):25-32.


Arachidonic and eicosapentaenoic acid metabolism by human CYP1A1: highly stereoselective formation of 17(R),18(S)-epoxyeicosatetraenoic acid.
Schwarz D, Kisselev P, Ericksen SS, Szklarz GD, Chernogolov A, Honeck H, Schunck WH, Roots I.
Biochem Pharmacol. 2004;67(8):1445-1457.


Effect of diesel exhaust particulate (DEP) on immune responses: contributions of particulate versus organic soluble components.
Siegel PD, Saxena RK, Saxena QB, Ma JK, Ma JY, Yin XJ, Castranova V, Al-Humadi NH, Lewis DM.
J Toxicol Environ Health A. 2004;67(3):221-231.


Production of macrophage IL-1beta was inhibited both at the levels of transcription and maturation by caspase-1 following inhalation exposure to isobutyl nitrite.
Soderberg LS, Ponnappan U, Roy A, Schafer R, Barnett JB.
Toxicol Lett. 2004;152(1):47-56.


Individually addressed large-scale patterning of conducting polymers by localized electric fields.
Su M, Fu L, Wu NQ, Aslam M, Dravid VP.
Appl Phys Lett. 2004;84(5):828-830.


Dip-pen nanopatterning of photosensitive conducting polymer using a monomer ink.
Su M, Aslam M, Fu L, Wu NQ, Dravid VP.
Appl Phys Lett. 2004;84(21):4200-4202.


ATR-FTIR characterization of transport properties of benzoic acid ion-pairs in silicone membranes.
Tantishaiyakul V, Phadoongsombut N, Wongpuwarak W, Thungtiwachgul J, Faroongsarng D, Wiwattanawongsa K, Rojanasakul Y.
Int J Pharm. 2004;283(1-2):111-116.


Stromal cell protection of B-lineage acute lymphoblastic leukemic cells during chemotherapy requires active Akt.
Wang L, Fortney JE, Gibson LF.
Leuk Res. 2004;28(7):733-742.


Failure detection of thermal barrier coatings using impedance spectroscopy.
Wu NQ, Ogawa K, Chyu MK, Mao SX.
Thin Solid Films. 2004;457(2):301-306.


Interfacial structure and micro and nano-mechanical behavior of laser-welded 6061 aluminum alloy blank.
Wu NQ, Xia C, Li M, Perrusquia N, Mao SX.
J Eng Mater-T ASME. 2004;126(1):8-13.


Interaction of fatty acid monolayers with cobalt nanoparticles.
Wu NQ, Fu L, Su M, Aslam M, Wong KC, Dravid VP.
Nano Lett. 2004;4(2):383-386.


Crystalline boron nanoribbons: Synthesis and characterization.
Xu TT, Zheng JG, Wu NQ, Nicholls AW, Roth JR, Dikin DA, Ruoff RS.
Nano Lett. 2004;4(5):963-968.


Roles of reactive oxygen species and heme oxygenase-1 in modulation of alveolar macrophage-mediated pulmonary immune responses to Listeria monocytogenes by diesel exhaust particles.
Yin XJ, Ma JY, Antonini JM, Castranova V, Ma JK.
Toxicol Sci. 2004;82(1):143-153.


Role of inducible nitric oxide synthase-derived nitric oxide in silica-induced pulmonary inflammation and fibrosis.
Zeidler P, Hubbs AF, Battelli LA, Castranova V.
J Toxicol Environ Health A. 2004;67(13):1001-1026.


Time-dependent apoptosis of alveolar macrophages from rats exposed to bleomycin: involvement of tnf receptor 2.
Zhao HW, Hu SY, Barger MW, Ma JK, Castranova V, Ma JY.
J Toxicol Environ Health A. 2004;67(17):1391-1406.


Internalization of caveolin-1 scaffolding domain facilitated by Antennapedia homeodomain attenuates PAF-induced increase in microvessel permeability.
Zhu L, Schwegler-Berry D, Castranova V, He P.
Am J Physiol Heart Circ Physiol. 2004;286(1):H195-H201.


The amide class herbicide 3,4-dichloropropionanilide (DCPA) alters the mobility of hydrocarbon chains in T-lymphocyte but not macrophage membranes.
Brundage KM, Barnett JB, Mahaney JE.
J Toxicol Environ Health A. 2003;66(23):2253-2265.


Inhibitor of nuclear factor kappaB kinase deficiency enhances oxidative stress and prolongs c-Jun NH2-terminal kinase activation induced by arsenic.
Chen F, Castranova V, Li Z, Karin M, Shi X.
Cancer Res. 2003;63(22):7689-7693.


Effect of Al2O3 overlay on hot-corrosion behavior of yttria-stabilized zirconia coating in molten sulfate-vanadate salt.
Chen Z, Wu NQ, Singh J, Mao SX.
Thin Solid Films. 2003;443(1-2):46-52.


Loss of pre-B and IgM(+) B cells in the bone marrow after exposure to a mixture of herbicides.
de la Rosa P, Barnett JB, Schafer R.
J Toxicol Environ Health A. 2003;66(24):2299-2313.


Adolescent nicotine dependence and smoking cessation outcomes.
Horn KA, Fernandes AW, Dino GA, Massey CJ, Kalsekar ID.
Addict Behav. 2003;28(4):769-776.


Synthesis and characterization of MCM-41-supported Ba2SiO4 base catalyst.
Li QC, Brown SE, Broadbelt LJ, Zheng JG, Wu NQ.
Micropor Mesopor Mat. 2003;59(2-3):105-111.


Characterization of substrate binding to cytochrome P450 1A1 using molecular modeling and kinetic analyses: case of residue 382.
Liu J, Ericksen SS, Besspiata D, Fisher CW, Szklarz GD.
Drub Metab Dispos. 2003;31(4):412-420.


Inhalation exposure of rats to asphalt fumes generated at paving temperatures alters pulmonary xenobiotic metabolism pathways without lung injury.
Ma JY, Rengasamy A, Frazer DG, Barger MW, Hubbs AF, Battelli LA, Tomblyn S, Stone S, Castranova V.
Environ Health Perspect. 2003;111(9):1215-1221.

PMC1241577.

Processing and mechanical behaviour of TiAl/NiAl intermetallic composites produced by cryogenic mechanical alloying.
Mao SX, Mcminn NA, Wu NQ.
Mat Sci Eng A-Struct. 2003;363(1-2):275-289.


Recruitment barriers and successes of the American Lung Association's Not-On-Tobacco Program.
Massey CJ, Dino GA, Horn KA, Lacey-McCracken A, Goldcamp J, Kalsekar ID.
J Sch Health. 2003;73(2):58-63.


Stochastic comparisons of Poisson and binomial random variables with their mixtures.
Misra N, Singh H, Harner EJ.
Statistics & Probability Letters. 2003;65(4):279-290.


Education and support needs of younger and older cancer survivors.
Narsavage GL, Romeo E.
Appl Nurs Res. 2003;16(2):103-109.


Smoking cessation interventions for hospitalized patients with cardio-pulmonary disorders.
Narsavage GL, Idemoto BK.
Online J Issues Nurs. 2003;8(2):8


Developing personal and community learning in graduate nursing education through community engagement.
Narsavage GL, Batchelor H, Lindell D, Chen YJ.
Nurs Educ Perspect. 2003;24(6):300-305.


APN-directed transitional home care model: achieving positive outcomes for patients with COPD.
Neff DF, Madigan E, Narsavage GL.
Home Healthc Nurse. 2003;21(8):543-550.


Diesel exhaust particle-induced alterations of pulmonary phase I and phase II enzymes of rats.
Rengasamy A, Barger MW, Kane E, Ma JK, Castranova V, Ma JY.
J Toxicol Environ Health A. 2003;66(2):153-167.


Asphalt exposure enhances neuropeptide levels in sensory neurons projecting to the rat nasal epithelium.
Sikora ER, Stone S, Tomblyn S, Frazer DG, Castranova V, Dey RD.
J Toxicol Environ Health A. 2003;66(11):1015-1027.


Synthesis and optical characterization of CdTe nanocrystals prepared by ball milling process.
Tan GL, Hommerich U, Temple D, Wu NQ, Zheng JG, Loutts G.
Scripta Materialia. 2003;48(10):1469-1474.


Vanadium-induced apoptosis and pulmonary inflammation in mice: Role of reactive oxygen species.
Wang LY, Medan D, Mercer RR, Overmiller D, Leornard S, Castranova V, Shi XL, Ding M, Huang C, Rojanasakul Y.
J Cell Physiol. 2003;195(1):99-107.


Potential role of apoptotic macrophages in pulmonary inflammation and fibrosis.
Wang LY, Antonini JM, Rojanasakul Y, Castranova V, Scabilloni JF, Mercer RR.
J Cell Physiol. 2003;194(2):215-224.


Inhibition of TNF-alpha gene expression and bioactivity by site-specific transcription factor-binding oligonucleotides.
Ye J, Wang LY, Zhang X, Tantishaiyakul V, Rojanasakul Y.
Am J Physiol Lung Cell Mol Physiol. 2003;284(2):L386-L394.


Response of alveolar macrophages from inducible nitric oxide synthase knockout or wild-type mice to an in vitro lipopolysaccharide or silica exposure.
Zeidler PC, Roberts JR, Castranova V, Chen F, Butterworth L, Andrew ME, Robinson VA, Porter DW.
J Toxicol Environ Health A. 2003;66(11):995-1013.


Antisense oligodeoxyribonucleotides: a better way to inhibit monocyte superoxide anion production?
Bey EA, Cathcart MK.
Methods Enzymol. 2002;353:421-434.


Pulmonary alterations associated with inhalation of occupational and environmental irritants.
Castranova V, Frazer DG, Manley LK, Dey RD.
Int Immunopharmacol. 2002;2(2-3):163-172.


Protective roles of NF-kappa B for chromium(VI)-induced cytotoxicity is revealed by expression of Ikappa B kinase-beta mutant.
Chen F, Bower JJ, Leonard SS, Ding M, Lu Y, Rojanasakul Y, Kung HF, Vallyathan V, Castranova V, Shi XL.
J Biol Chem. 2002;277(5):3342-3349.


Arsenite-induced Cdc25C degradation is through the KEN-box and ubiquitin-proteasome pathway.
Chen F, Zhang Z, Bower JJ, Lu Y, Leonard SS, Ding M, Castranova V, Piwnica-Worms H, Shi XL.
Proc Natl Acad Sci USA. 2002;99(4):1990-1995.

PMC122307.

Differential role of hydrogen peroxide in UV-induced signal transduction.
Ding M, Li J, Leonard SS, Shi XL, Costa M, Castranova V, Vallyathan V, Huang C.
Mol Cell Biochem. 2002;234-235(1-2):81-90.


New obesity center at WVU offering comprehensive program.
Dino GA, Cohen D, Tessaro I, Ducatman AM.
WV Med J. 2002;98(6):288-289.


Effect of strain gradients and heterogeneity on flow strength of particle reinforced metal-matrix composites.
Duan DM, Wu NQ, Zhao MH, Slaughter WS, Mao SX.
J Eng Mater-T ASME. 2002;124(2):167-173.


p38 Signaling-mediated hypoxia-inducible factor 1alpha and vascular endothelial growth factor induction by Cr(VI) in DU145 human prostate carcinoma cells.
Gao N, Jiang BH, Leonard SS, Corum L, Zhang Z, Roberts JR, Antonini JM, Zheng JZ, Flynn DC, Castranova V, Shi XL.
J Biol Chem. 2002;277(47):45041-45048.


Comment on Peterson et al. (2001) - 'Sampling design begets conclusions'.
Gilfillan ES, Harner EJ, Page DS.
Mar Ecol-Prog Ser. 2002;231:303-308.


Ultraviolet-induced phosphorylation of p70(S6K) at Thr(389) and Thr(421)/Ser(424) involves hydrogen peroxide and mammalian target of rapamycin but not Akt and atypical protein kinase C.
Huang C, Li J, Ke Q, Leonard SS, Jiang BH, Zhong XS, Costa M, Castranova V, Shi XL.
Cancer Res. 2002;62(20):5689-5697.


Antioxidant properties of fruit and vegetable juices: more to the story than ascorbic acid.
Leonard SS, Cutler D, Ding M, Vallyathan V, Castranova V, Shi XL.
Ann Clin Lab Sci. 2002;32(2):193-200.


Length-scale-controlled interfacial toughening and weakening in metal/ceramic layered materials.
Li MZ, Wu NQ, Mao SX.
Philos Mag A. 2002;82(5):1049-1071.


Regulation of Fas (CD95)-induced apoptosis by nuclear factor-kappaB and tumor necrosis factor-alpha in macrophages.
Lu B, Wang LY, Medan D, Toledo D, Huang C, Chen F, Shi XL, Rojanasakul Y.
Am J Physiol Cell Physiol. 2002;283(3):C831-C838.


Alteration of pulmonary cytochrome p-450 system: effects of asphalt fume condensate exposure.
Ma JY, Yang HM, Barger MW, Siegel PD, Zhong BZ, Kriech AJ, Castranova V.
J Toxicol Environ Health A. 2002;65(17):1247-1260.


Induction of neutrophil apoptosis and secondary necrosis during endotoxin-induced pulmonary inflammation in mice.
Medan D, Wang LY, Yang X, Dokka S, Castranova V, Rojanasakul Y.
J Cell Physiol. 2002;191(3):320-326.


A community engagement initiative: service-learning in graduate nursing education.
Narsavage GL, Lindell D, Chen YJ, Savrin C, Duffy E.
J Nurs Educ. 2002;41(10):457-461.


Enhanced nitric oxide and reactive oxygen species production and damage after inhalation of silica.
Porter DW, Millecchia L, Robinson VA, Hubbs AF, Willard P, Pack D, Ramsey D, McLaurin J, Khan A, Landsittel D, Teass A, Castranova V.
Am J Physiol Lung Cell Mol Physiol. 2002;283(2):L485-L493.


Time course of pulmonary response of rats to inhalation of crystalline silica: NF-kappa B activation, inflammation, cytokine production, and damage.
Porter DW, Ye J, Ma J, Barger MW, Robinson VA, Ramsey DM, McLaurin JL, Khan A, Landsittel DP, Teass A, Castranova V.
Inhal Toxicol. 2002;14(4):349-367.


Molecular modeling of cytochrome P450 1A1: enzyme-substrate interactions and substrate binding affinities.
Szklarz GD, Paulsen MD.
J Biomol Struct Dyn. 2002;20(2):155-162.


Characterization of mefenamic acid-guaiacol ester: stability and transport across Caco-2 cell monolayers.
Tantishaiyakul V, Wiwattanawongsa K, Pinsuwan S, Kasiwong S, Phadoongsombut N, Kaewnopparat S, Kaewnopparat N, Rojanasakul Y.
Pharm Res. 2002;19(7):1013-1018.


Role of neutrophil apoptosis in vanadium-induced pulmonary inflammation in mice.
Wang LY, Medan D, Mercer RR, Shi XL, Huang C, Castranova V, Ding M, Rojanasakul Y.
J Environ Pathol Toxicol Oncol. 2002;21(4):343-350.


Modified endotoxin responses in rats pretreated with 1-->3-beta-glucan (zymosan A).
Young SH, Robinson VA, Barger M, Zeidler P, Porter DW, Frazer DG, Castranova V.
Toxicol Appl Pharmacol. 2002;178(3):172-179.


Cytosolic phospholipase A2 (cPLA2) regulation of human monocyte NADPH oxidase activity. cPLA2 affects translocation but not phosphorylation of p67(phox) and p47(phox).
Zhao X, Bey EA, Wientjes FB, Cathcart MK.
J Biol Chem. 2002;277(28):25385-25392.


Effect of exposure to diesel exhaust particles on the susceptibility of the lung to infection.
Castranova V, Ma JY, Yang HM, Antonini JM, Butterworth L, Barger MW, Roberts J, Ma JK.
Environ Health Perspect. 2001;109 Suppl 4:609-612.

PMC1240590.

Opposite effect of NF-kappa B and c-Jun N-terminal kinase on p53-independent GADD45 induction by arsenite.
Chen F, Lu Y, Zhang Z, Vallyathan V, Ding M, Castranova V, Shi XL.
J Biol Chem. 2001;276(14):11414-11419.


Carcinogenic metals and NF-kappaB activation.
Chen F, Ding M, Castranova V, Shi XL.
Mol Cell Biochem. 2001;222(1-2):159-171.


Induction of activator protein-1 through reactive oxygen species by crystalline silica in JB6 cells.
Ding M, Shi XL, Lu Y, Huang C, Leonard SS, Roberts J, Antonini JM, Castranova V, Vallyathan V.
J Biol Chem. 2001;276(12):9108-9114.


Statewide demonstration of not on tobacco: a gender-sensitive teen smoking cessation program.
Dino GA, Horn KA, Goldcamp J, Maniar SD, Fernandes AW, Massey CJ.
J Sch Nurs. 2001;17(2):90-97.


A 2-year efficacy study of Not On Tobacco in Florida: an overview of program successes in changing teen smoking behavior.
Dino GA, Horn KA, Goldcamp J, Fernandes AW, Kalsekar ID, Massey CJ.
Prev Med. 2001;33(6):600-605.


Teen smoking cessation: making it work through school and community partnerships.
Dino GA, Horn KA, Goldcamp J, Kemp-Rye L, Westrate S, Monaco K.
J Public Health Manag Pract. 2001;7(2):71-80.


Interleukin-10-mediated inhibition of free radical generation in macrophages.
Dokka S, Shi XL, Leonard SS, Wang LY, Castranova V, Rojanasakul Y.
Am J Physiol Lung Cell Mol Physiol. 2001;280(6):L1196-L1202.


Length scale effect on mechanical behavior due to strain gradient plasticity.
Duan DM, Wu NQ, Slaughter WS, Mao SX.
Mat Sci Eng A-Struct. 2001;303(1-2):241-249.


Propanil inhibits tumor necrosis factor-alpha production by reducing nuclear levels of the transcription factor nuclear factor-kappab in the macrophage cell line ic-21.
Frost LL, Neeley YX, Schafer R, Gibson LF, Barnett JB.
Toxicol Appl Pharmacol. 2001;172(3):186-193.


Arsenic-induced NFkappaB transactivation through Erks- and JNKs-dependent pathways in mouse epidermal JB6 cells.
Huang C, Li J, Ding M, Wang LY, Shi XL, Castranova V, Vallyathan V, Ju G, Costa M.
Mol Cell Biochem. 2001;222(1-2):29-34.


Vanadium-induced nuclear factor of activated T cells activation through hydrogen peroxide.
Huang C, Ding M, Li J, Leonard SS, Rojanasakul Y, Castranova V, Vallyathan V, Ju G, Shi XL.
J Biol Chem. 2001;276(25):22397-22403.


Transactivation of RARE and GRE in the cellular response to arsenic.
Huang C, Li J, Ding M, Costa M, Castranova V, Vallyathan V, Ju G, Shi XL.
Mol Cell Biochem. 2001;222(1-2):119-125.


UV Induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide.
Huang C, Li J, Ding M, Leonard SS, Wang LY, Castranova V, Vallyathan V, Shi XL.
J Biol Chem. 2001;276(43):40234-40240.


Involvement of sphingomyelinase in insulin-induced phosphatidylinositol 3-kinase activation.
Huang C, Ma WY, Ding M, Li J, Shi XL, Castranova V, Vallyathan V, Bode AM, Dong ZG.
FASEB J. 2001;15(6):1113-1114.


Immunoglobulin responses to experimental silicosis.
Huang SH, Hubbs AF, Stanley CF, Vallyathan V, Schnabel PC, Rojanasakul Y, Ma JK, Banks DE, Weissman DN.
Toxicol Sci. 2001;59(1):108-117.


Comparative pulmonary toxicity of 6 abrasive blasting agents.
Hubbs AF, Minhas NS, Jones W, Greskevitch M, Battelli LA, Porter DW, Goldsmith WT, Frazer DG, Landsittel DP, Ma JY, Barger MW, Hill K, Schwegler-Berry D, Robinson VA, Castranova V.
Toxicol Sci. 2001;61(1):135-143.


On the mechanism of Cr (VI)-induced carcinogenesis: dose dependence of uptake and cellular responses.
Liu K, Husler J, Ye J, Leonard SS, Cutler D, Chen F, Wang S, Zhang Z, Ding M, Wang L, Shi XL.
Mol Cell Biochem. 2001;222(1-2):221-229.


The mechanism of hydrogen-facilitated anodic-dissolution-type stress corrosion cracking: theories and experiments.
Mao SX, Gu B, Wu NQ, Qiao L.
Philos Mag A. 2001;81(7):1813-1831.


High prevalence of RET tyrosine kinase activation in Mexican patients with papillary thyroid carcinomas.
Martinez I, Mantilla A, Medrano ME, Hernandez R, Hernandez DM, Lazos M, Santiago H, Gonzalez B, Hidalgo A, Salcedo M.
Endocr Pathol. 2001;12(2):113-123.


Time course of pulmonary response of rats to inhalation of crystalline silica: histological results and biochemical indices of damage, lipidosis, and fibrosis.
Porter DW, Ramsey D, Hubbs AF, Battelli L, Ma J, Barger M, Landsittel D, Robinson VA, McLaurin J, Khan A, Jones W, Teass A, Castranova V.
J Environ Pathol Toxicol Oncol. 2001;20 Suppl 1:1-14.


Cr (VI) increases tyrosine phosphorylation through reactive oxygen species-mediated reactions.
Qian Y, Jiang BH, Flynn DC, Leonard SS, Wang S, Zhang Z, Ye J, Chen F, Wang L, Shi XL.
Mol Cell Biochem. 2001;222(1-2):199-204.


A cell-based drug delivery system for lung targeting: II. Therapeutic activities on B16-F10 melanoma in mouse lungs.
Shao J, DeHaven JI, Lamm DL, Weissman DN, Malanga CJ, Rojanasakul Y, Ma JK.
Drub Deliv. 2001;8(2):71-76.


A cell-based drug delivery system for lung targeting: I. Preparation and pharmacokinetics.
Shao J, DeHaven JI, Lamm DL, Weissman DN, Runyan K, Malanga CJ, Rojanasakul Y, Ma JK.
Drub Deliv. 2001;8(2):61-69.


Reactive oxygen species and molecular mechanism of silica-induced lung injury.
Shi XL, Ding M, Chen F, Wang LY, Rojanasakul Y, Vallyathan V, Castranova V.
J Environ Pathol Toxicol Oncol. 2001;20 Suppl 1:85-93.


Inhibition of nuclear transcription factor-kappaB by specific IkappaB kinase peptide inhibitor.
Swaroop N, Chen F, Wang LY, Dokka S, Toledo D, Rojanasakul Y.
Pharm Res. 2001;18(11):1631-1633.


IgG subclass responses in experimental silicosis.
Weissman DN, Hubbs AF, Huang SH, Stanley CF, Rojanasakul Y, Ma JK.
J Environ Pathol Toxicol Oncol. 2001;20 Suppl 1:67-74.


Influence of P450 3A4 SRS-2 residues on cooperativity and/or regioselectivity of aflatoxin B(1) oxidation.
Xue L, Wang HF, Wang Q, Szklarz GD, Domanski TL, Halpert JR, Correia MA.
Chem Res Toxicol. 2001;14(5):483-491.


Diesel exhaust particles suppress macrophage function and slow the pulmonary clearance of Listeria monocytogenes in rats.
Yang HM, Antonini JM, Barger MW, Butterworth L, Roberts BR, Ma JK, Castranova V, Ma JY.
Environ Health Perspect. 2001;109(5):515-521.

PMC1240312.

Rapid and sensitive assay of tumor necrosis factor-alpha gene transcription.
Zhang X, Ye J, Wang LY, Manosroi J, Shi XL, Rojanasakul Y.
Pharm Res. 2001;18(3):408-411.


Effect of silica inhalation on the pulmonary clearance of a bacterial pathogen in Fischer 344 rats.
Antonini JM, Roberts JR, Yang HM, Barger MW, Ramsey DM, Castranova V, Ma JY.
Lung. 2000;178(6):341-350.


In vitro knockout of human p47phox blocks superoxide anion production and LDL oxidation by activated human monocytes.
Bey EA, Cathcart MK.
J Lipid Res. 2000;41(3):489-495.


Participation of MAP kinase p38 and IkappaB kinase in chromium (VI)-induced NF-kappaB and AP-1 activation.
Chen F, Ding M, Lu Y, Leonard SS, Vallyathan V, Castranova V, Shi XL.
J Environ Pathol Toxicol Oncol. 2000;19(3):231-238.


Impairment of NF-kappaB activation and modulation of gene expression by calpastatin.
Chen F, Demers LM, Vallyathan V, Lu Y, Castranova V, Shi XL.
Am J Physiol Cell Physiol. 2000;279(3):C709-C716.


Predisposing factors in occupational lung cancer: inorganic minerals and chromium.
Ding M, Shi XL, Castranova V, Vallyathan V.
J Environ Pathol Toxicol Oncol. 2000;19(1-2):129-138.


Inhibition of endotoxin-induced lung inflammation by interleukin-10 gene transfer in mice.
Dokka S, Malanga CJ, Shi XL, Chen F, Castranova V, Rojanasakul Y.
Am J Physiol Lung Cell Mol Physiol. 2000;279(5):L872-L877.


Free radical-mediated transgene inactivation of macrophages by endotoxin.
Dokka S, Toledo D, Wang LY, Shi XL, Huang C, Leonard SS, Rojanasakul Y.
Am J Physiol Lung Cell Mol Physiol. 2000;279(5):L878-L883.


Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes.
Dokka S, Toledo D, Shi XL, Castranova V, Rojanasakul Y.
Pharm Res. 2000;17(5):521-525.


Novel non-endocytic delivery of antisense oligonucleotides.
Dokka S, Rojanasakul Y.
Adv Drug Deliv Rev. 2000;44(1):35-49.


High-efficiency gene transfection of macrophages by lipoplexes.
Dokka S, Toledo D, Shi XL, Ye J, Rojanasakul Y.
Int J Pharm. 2000;206(1-2):97-104.


Acute exposure to the abused inhalant, isobutyl nitrite, reduced T cell responsiveness and spleen cellularity.
Guo GL, Rose D, Flick JT, Barnett JB, Soderberg LS.
Toxicol Lett. 2000;116(1-2):151-158.


Determinants of youth tobacco use in West Virginia: a comparison of smoking and smokeless tobacco use.
Horn KA, Gao X, Dino GA, Kamal-Bahl S.
Am J Drug Alcohol Abuse. 2000;26(1):125-138.


Coaches' attitudes toward smokeless tobacco and intentions to intervene with athletes.
Horn KA, Maniar SD, Dino GA, Gao X, Meckstroth RL.
J Sch Health. 2000;70(3):89-94.


Vanadate induces p53 transactivation through hydrogen peroxide and causes apoptosis.
Huang C, Zhang Z, Ding M, Li J, Ye J, Leonard SS, Shen HM, Butterworth L, Lu Y, Costa M, Rojanasakul Y, Castranova V, Vallyathan V, Shi XL.
J Biol Chem. 2000;275(42):32516-32522.


Silica induces nuclear factor-kappa B activation through tyrosine phosphorylation of I kappa B-alpha in RAW264.7 macrophages.
Kang JL, Pack IS, Hong SM, Lee HS, Castranova V.
Toxicol Appl Pharmacol. 2000;169(1):59-65.


Effects of asphalt fume condensate exposure on acute pulmonary responses.
Ma JY, Barger MW, Kriech AJ, Castranova V.
Arch Toxicol. 2000;74(8):452-459.


Cardiovascular health for older adults.
Narsavage GL.
J Gerontol Nurs. 2000;26(5):5-6.


Factors associated with referral of elderly individuals with cardiac and pulmonary disorders for home care services following hospital discharge.
Narsavage GL, Naylor MD.
J Gerontol Nurs. 2000;26(5):14-20.


Cellular delivery of functional peptides to block cytokine gene expression.
Rojanasakul Y, Luo Q, Ye J, Antonini JM, Toledo D.
J Control Release. 2000;65(1-2):13-17.


Antioxidant properties of (-)-epicatechin-3-gallate and its inhibition of Cr(VI)-induced DNA damage and Cr(IV)- or TPA-stimulated NF-kappaB activation.
Shi XL, Ye J, Leonard SS, Ding M, Vallyathan V, Castranova V, Rojanasakul Y, Dong ZG.
Mol Cell Biochem. 2000;206(1-2):125-132.


Nitrite inhalants spontaneously liberate nitric oxide, which is not responsible for the immunotoxicity in C57BL/6 mice.
Soderberg LS, Roy A, Flick JT, Barnett JB.
Int J Immunopharmacol. 2000;22(2):151-157.


Molecular modeling of mammalian cytochromes P450: application to study enzyme function.
Szklarz GD, Graham SE, Paulsen MD.
Vitam Horm. 2000;58:53-87.


In vivo cytokine production and resistance to infection after acute exposure to 3,4-dichloropropionaniline.
Watson VA, Barnett JB, Schafer R.
J Toxicol Environ Health A. 2000;60(6):391-406.


Characterization of proteolytic activities of pulmonary alveolar epithelium.
Yang X, Ma JK, Malanga CJ, Rojanasakul Y.
Int J Pharm. 2000;195(1-2):93-101.


On the role of hydroxyl radical and the effect of tetrandrine on nuclear factor--kappaB activation by phorbol 12-myristate 13-acetate.
Ye J, Ding M, Zhang X, Rojanasakul Y, Shi XL.
Ann Clin Lab Sci. 2000;30(1):65-71.


Vanadate induction of NF-kappaB involves IkappaB kinase beta and SAPK/ERK kinase 1 in macrophages.
Chen F, Demers LM, Vallyathan V, Ding M, Lu Y, Castranova V, Shi XL.
J Biol Chem. 1999;274(29):20307-20312.


Nitric oxide inhibits HIV tat-induced NF-kappaB activation.
Chen F, Lu Y, Castranova V, Rojanasakul Y, Miyahara K, Shizuta Y, Vallyathan V, Shi XL, Demers LM.
Am J Pathol. 1999;155(1):275-284.

PMC1866645.

Involvement of 5'-flanking kappaB-like sites within bcl-x gene in silica-induced Bcl-x expression.
Chen F, Demers LM, Vallyathan V, Lu Y, Castranova V, Shi XL.
J Biol Chem. 1999;274(50):35591-35595.


Role of transcription factor NF-kappaB in asbestos-induced TNFalpha response from macrophages.
Cheng N, Shi XL, Ye J, Castranova V, Chen F, Leonard SS, Vallyathan V, Rojanasakul Y.
Exp Mol Pathol. 1999;66(3):201-210.


Asbestos induces activator protein-1 transactivation in transgenic mice.
Ding M, Dong ZG, Chen F, Pack DL, Ma WY, Ye J, Shi XL, Castranova V, Vallyathan V.
Cancer Res. 1999;59(8):1884-1889.


Vanadate-induced activation of activator protein-1: role of reactive oxygen species.
Ding M, Li JJ, Leonard SS, Ye JP, Shi XL, Colburn NH, Castranova V, Vallyathan V.
Carcinogenesis. 1999;20(4):663-668.


Freshly fractured crystalline silica induces activator protein-1 activation through ERKs and p38 MAPK.
Ding M, Shi XL, Dong ZG, Chen F, Lu Y, Castranova V, Vallyathan V.
J Biol Chem. 1999;274(43):30611-30616.


A comparison of shoreline assessment study designs used for the Exxon Valdez oil spill.
Gilfillan ES, Harner EJ, O'Reilly JE, Page DS, Burns WA.
Marine Pollut Bull. 1999;38(5):380-388.


Use of tetrandrine to differentiate between mechanisms involved in silica-versus bleomycin-induced fibrosis.
Ma JY, Barger MW, Hubbs AF, Castranova V, Weber SL, Ma JK.
J Toxicol Environ Health A. 1999;57(4):247-266.


There is no need to be normal: Generalized linear models of natural variation.
Parker KR, Maki AW, Harner EJ.
Human and Ecological Risk Assessment. 1999;5(2):355-374.


Dependence of NF-kappaB activation and free radical generation on silica-induced TNF-alpha production in macrophages.
Rojanasakul Y, Ye J, Chen F, Wang LY, Cheng N, Castranova V, Vallyathan V, Shi XL.
Mol Cell Biochem. 1999;200(1-2):119-125.


Cr(IV) causes activation of nuclear transcription factor-kappa B, DNA strand breaks and dG hydroxylation via free radical reactions.
Shi XL, Ding M, Ye J, Wang S, Leonard SS, Zang L, Castranova V, Vallyathan V, Chiu A, Dalal NS, Liu K.
J Inorg Biochem. 1999;75(1):37-44.


Antioxidant properties of aspirin: characterization of the ability of aspirin to inhibit silica-induced lipid peroxidation, DNA damage, NF-kappaB activation, and TNF-alpha production.
Shi XL, Ding M, Dong ZG, Chen F, Ye J, Wang S, Leonard SS, Castranova V, Vallyathan V.
Mol Cell Biochem. 1999;199(1-2):93-102.


The role of hydroxyl radical as a messenger in the activation of nuclear transcription factor NF-kappaB.
Shi XL, Dong ZG, Huang C, Ma W, Liu K, Ye J, Chen F, Leonard SS, Ding M, Castranova V, Vallyathan V.
Mol Cell Biochem. 1999;194(1-2):63-70.


Identification of selective mechanism-based inactivators of cytochromes P-450 2B4 and 2B5, and determination of the molecular basis for differential susceptibility.
Strobel SM, Szklarz GD, He Y, Foroozesh M, Alworth WL, Roberts ES, Hollenberg PF, Halpert JR.
J Pharmacol Exp Ther. 1999;290(1):445-451.


A collaborative partnership to enhance school-based tobacco control policies in West Virginia. Center for Disease Control and Prevention.
Tompkins NO, Dino GA, Zedosky LK, Harman M, Shaler G.
Am J Prev Med. 1999;16(3 Suppl):29-34.


Reduction reaction in Al-CuO powder mixture driven by mechanical alloying.
Wu JM, Zheng SL, Li ZZ, Wu NQ.
T Nonferr Metal Soc. 1999;9(4):717-722.


Effects of diesel exhaust particles (DEP), carbon black, and silica on macrophage responses to lipopolysaccharide: evidence of DEP suppression of macrophage activity.
Yang HM, Barger MW, Castranova V, Ma JK, Yang JJ, Ma JY.
J Toxicol Environ Health A. 1999;58(5):261-278.


Critical role of glass fiber length in TNF-alpha production and transcription factor activation in macrophages.
Ye J, Shi XL, Jones W, Rojanasakul Y, Cheng N, Schwegler-Berry D, Baron PA, Deye GJ, Li C, Castranova V.
Am J Physiol. 1999;276(3 Pt 1):L426-L434.


Vanadate induces apoptosis in epidermal JB6 P+ cells via hydrogen peroxide-mediated reactions.
Ye J, Ding M, Leonard SS, Robinson VA, Millecchia LL, Zhang X, Castranova V, Vallyathan V, Shi XL.
Mol Cell Biochem. 1999;202(1-2):9-17.


Role of reactive oxygen species and p53 in chromium(VI)-induced apoptosis.
Ye J, Wang S, Leonard SS, Sun Y, Butterworth L, Antonini JM, Ding M, Rojanasakul Y, Vallyathan V, Castranova V, Shi XL.
J Biol Chem. 1999;274(49):34974-34980.


Induction of TNFalpha in macrophages by vanadate is dependent on activation of transcription factor NF-kappaB and free radical reactions.
Ye J, Ding M, Zhang X, Rojanasakul Y, Nedospasov S, Vallyathan V, Castranova V, Shi XL.
Mol Cell Biochem. 1999;198(1-2):193-200.


Propanil affects transcriptional and posttranscriptional regulation of IL-2 expression in activated EL-4 cells.
Zhao W, Schafer R, Barnett JB.
Toxicol Appl Pharmacol. 1999;154(2):153-159.


Enhancement of nitric oxide production by pulmonary cells following silica exposure.
Castranova V, Huffman LJ, Judy DJ, Bylander JE, Lapp LN, Weber SL, Blackford JA, Dey RD.
Environ Health Perspect. 1998;106 Suppl 5:1165-1169.

PMC1533358.

Role of hydroxyl radical in silica-induced NF-kappa B activation in macrophages.
Chen F, Lu Y, Demers LM, Rojanasakul Y, Shi X, Vallyathan V, Castranova V.
Ann Clin Lab Sci. 1998;28(1):1-13.


Enteric reovirus infection as a probe to study immunotoxicity of the gastrointestinal tract.
Cuff CF, Fulton JR, Barnett JB, Boyce CS.
Toxicol Sci. 1998;42(2):99-108.


Validity of the numeric rating scale as a measure of dyspnea.
Gift AG, Narsavage GL.
Am J Crit Care. 1998;7(3):200-204.


Structural determinants of progesterone hydroxylation by cytochrome P450 2B5: the role of nonsubstrate recognition site residues.
He YQ, Harlow GR, Szklarz GD, Halpert JR.
Arch Biochem Biophys. 1998;350(2):333-339.


Presence of the 918 mutation in the RET proto-oncogene in a Mexican patient with multiple endocrine neoplasia type 2B.
Hidalgo A, Medrano ME, Rodriguez S, Franco C, Martinez I, Benitez L, Salcedo M.
J Exp Clin Cancer Res. 1998;17(2):149-152.


Effects of silica exposure on substance P immunoreactivity and preprotachykinin mRNA expression in trigeminal sensory neurons in Fischer 344 rats.
Hunter DD, Castranova V, Stanley CF, Dey RD.
J Toxicol Environ Health A. 1998;53(8):593-605.


Probing the active site of cytochrome P450 2B1: metabolism of 7-alkoxycoumarins by the wild type and five site-directed mutants.
Kobayashi Y, Fang X, Szklarz GD, Halpert JR.
Biochemistry. 1998;37(19):6679-6688.


Health management education and reformation of nursing education in the Slovak Republic.
Konosova H, Narsavage GL.
J Health Adm Educ. 1998;16(2):235-241.


Cobalt-mediated generation of reactive oxygen species and its possible mechanism.
Leonard SS, Gannett PM, Rojanasakul Y, Schwegler-Berry D, Castranova V, Vallyathan V, Shi X.
J Inorg Biochem. 1998;70(3-4):239-244.


Reactive oxygen species and silica-induced carcinogenesis.
Shi X, Castranova V, Halliwell B, Vallyathan V.
J Toxicol Environ Health B Crit Rev. 1998;1(3):181-197.


Isobutyl nitrite liberates nitric oxide which is not responsible for the immunotoxicity of the inhalant.
Soderberg LS, Roy A, Barnett JB.
Adv Exp Med Biol. 1998;437:265-268.


Redistribution of mercury from contaminated lake sediments of Clear Lake, California.
Suchanek TH, Mullen LH, Lamphere BA, Richerson PJ, Woodmansee CE, Slotton DG, Harner EJ, Woodward LA.
Water Air Soil Poll. 1998;104(1-2):77-102.


Molecular basis of P450 inhibition and activation: implications for drug development and drug therapy.
Szklarz GD, Halpert JR.
Drub Metab Dispos. 1998;26(12):1179-1184.


The development and psychometric evaluation of the Pulmonary Functional Status Scale: an instrument to assess functional status in pulmonary disease.
Weaver TE, Narsavage GL, Guilfoyle MJ.
J Cardiopulm Rehabil. 1998;18(2):105-111.


Mechanosynthesis mechanism of TiC powders.
Wu NQ, Lin S, Wu JM, Li ZZ.
Mat Sci Tech Ser. 1998;14(4):287-291.


Dry sliding wear of PM Al-10Ti alloy.
Wu NQ, Wu JM, Lin S, Zhou JQ, Li ZZ.
T Nonferr Metal Soc. 1998;8(3):421-426.


Preparation and microstructure of nano-sized Cu particles by mechanochemical reaction.
Wu NQ, Su LZ, Yuan MY, Liu YY, Wu JM, Li ZZ.
T Nonferr Metal Soc. 1998;8(4):610-612.


Enzymatic degradation of luteinizing hormone releasing hormone (LHRH)/[D-Ala6]-LHRH in lung pneumocytes.
Yang X, Rojanasakul Y, Wang LY, Ma JY, Ma JK.
Pharm Res. 1998;15(9):1480-1484.


Cytokine production by C57BL/6 mouse spleen cells is selectively reduced by exposure to propanil.
Zhao W, Schafer R, Barnett JB.
J Toxicol Environ Health A. 1998;55(2):107-120.


Comparison of inducible nitric oxide synthase gene expression and lung inflammation following intratracheal instillation of silica, coal, carbonyl iron, or titanium dioxide in rats.
Blackford JA, Jones W, Dey RD, Castranova V.
J Toxicol Environ Health. 1997;51(3):203-218.


Augmentation of pulmonary reactions to quartz inhalation by trace amounts of iron-containing particles.
Castranova V, Vallyathan V, Ramsey DM, McLaurin JL, Pack DL, Leonard SS, Barger MW, Ma JY, Dalal NS, Teass A.
Environ Health Perspect. 1997;105 Suppl 5:1319-1324.

PMC1470157.

One-electron reduction of chromium(VI) by alpha-lipoic acid and related hydroxyl radical generation, dG hydroxylation and nuclear transcription factor-kappaB activation.
Chen F, Ye J, Zhang X, Rojanasakul Y, Shi X.
Arch Biochem Biophys. 1997;338(2):165-172.


Effects of the Exxon Valdez oil spill on habitat use by birds in Prince William Sound, Alaska.
Day RH, Murphy SM, Wiens JA, Hayward GD, Harner EJ, Smith LN.
Ecol Appl. 1997;7(2):593-613.


Effects of the Exxon Valdez oil spill on habitat use by birds along the Kenai peninsula, Alaska.
Day RH, Murphy SM, Wiens JA, Hayward GD, Harner EJ, Lawhead BE.
Condor. 1997;99(3):728-742.


Cellular delivery of oligonucleotides by synthetic import peptide carrier.
Dokka S, Toledo-Velasquez D, Shi XL, Wang LY, Rojanasakul Y.
Pharm Res. 1997;14(12):1759-1764.


Identification of three key residues in substrate recognition site 5 of human cytochrome P450 3A4 by cassette and site-directed mutagenesis.
He YA, He YQ, Szklarz GD, Halpert JR.
Biochemistry. 1997;36(29):8831-8839.


Acute lung injury induced by a commercial leather conditioner.
Hubbs AF, Castranova V, Ma JY, Frazer DG, Siegel PD, Ducatman BS, Grote A, Schwegler-Berry D, Robinson VA, Van Dyke C, Barger MW, Xiang J, Parker J.
Toxicol Appl Pharmacol. 1997;143(1):37-46.


Significance of glycine 478 in the metabolism of N-benzyl-1-aminobenzotriazole to reactive intermediates by cytochrome P450 2B1.
Kent UM, Hanna IH, Szklarz GD, Vaz AD, Halpert JR, Bend JR, Hollenberg PF.
Biochemistry. 1997;36(39):11707-11716.


Promoting function in clients with chronic lung disease by increasing their perception of control.
Narsavage GL.
Holist Nurs Pract. 1997;12(1):17-26.


Antisense inhibition of silica-induced tumor necrosis factor in alveolar macrophages.
Rojanasakul Y, Weissman DN, Shi XL, Castranova V, Ma JK, Liang WW.
J Biol Chem. 1997;272(7):3910-3914.


Efficacy of taurine based compounds as hydroxyl radical scavengers in silica induced peroxidation.
Shi XL, Flynn DC, Porter DW, Leonard SS, Vallyathan V, Castranova V.
Ann Clin Lab Sci. 1997;27(5):365-374.


Use of homology modeling in conjunction with site-directed mutagenesis for analysis of structure-function relationships of mammalian cytochromes P450.
Szklarz GD, Halpert JR.
Life Sci. 1997;61(26):2507-2520.


Molecular modeling of cytochrome P450 3A4.
Szklarz GD, Halpert JR.
J Comput Aided Mol Des. 1997;11(3):265-272.


An explanatory model of functional status in chronic obstructive pulmonary disease.
Weaver TE, Richmond TS, Narsavage GL.
Nurs Res. 1997;46(1):26-31.


In-situ observation of single-point wear of PM Al-Ti alloy.
Wu JM, Wu NQ, Wang GX, Li ZZ.
T Nonferr Metal Soc. 1997;7(3):69-74.


Mechanically driven synthesis of nanophase TiC/Ti-Al composite powder.
Wu NQ, Wang GX, Li W, Wu JM, Li ZZ.
Mater Lett. 1997;32(4):259-262.


Oxidation of PM alloy Al-10Ti during sliding wear.
Wu NQ, Wang GX, Li ZZ.
T Nonferr Metal Soc. 1997;7(1):82-86.


Formation of a FCC Al54Ti23C23 metastable phase by ball milling.
Wu NQ, Li ZZ, Wang GX, Mu JM.
J Mater Sci Technol. 1997;13(4):345-347.


Amorphization of Al4C3 by mechanical milling.
Wu NQ.
J Mater Sci Lett. 1997;16(22):1810-1812.


Microstructure and sliding wear behavior of PM alloy Al-10Ti after thermal exposure.
Wu NQ, Wang GX, Li ZZ, Wu JM.
Wear. 1997;203:155-161.


Investigation of TiC formation during ball-milling of elemental titanium and carbon.
Wu NQ, Wang GX, Wu JM, Li ZZ, Yuan MY.
Int J Refract Met H. 1997;15(5-6):289-293.


Preparation of Ti/Al based nanophase composite powder by mechanical alloying.
Wu NQ, Wu JM, Li W, Wang GX, Li ZZ.
T Nonferr Metal Soc. 1997;7(4):1-4.


Inhibitory effect of 3,4-dichloro-propionaniline on cytokine production by macrophages is associated with LPS-mediated signal transduction.
Xie YC, Schafer R, Barnett JB.
J Leukoc Biol. 1997;61(6):745-752.


The immunomodulatory effects of the herbicide propanil on murine macrophage interleukin-6 and tumor necrosis factor-alpha production.
Xie YC, Schafer R, Barnett JB.
Toxicol Appl Pharmacol. 1997;145(1):184-191.


Effects of diesel exhaust particles on the release of interleukin-1 and tumor necrosis factor-alpha from rat alveolar macrophages.
Yang HM, Ma JY, Castranova V, Ma JK.
Exp Lung Res. 1997;23(3):269-284.


Pulmonary reactions to organic dust exposures: development of an animal model.
Castranova V, Robinson VA, Frazer DG.
Environ Health Perspect. 1996;104 Suppl 1:41-53.

PMC1469574.

3,4-Dichloropropionanilide-induced atrophy of the thymus: mechanisms of toxicity and recovery.
Cuff CF, Zhao W, Nukui T, Schafer R, Barnett JB.
Fundam Appl Toxicol. 1996;33(1):83-90.


Enhanced cellular uptake of oligonucleotides by EGF receptor-mediated endocytosis in A549 cells.
Deshpande D, Toledo-Velasquez D, Thakkar DD, Liang WW, Rojanasakul Y.
Pharm Res. 1996;13(1):57-61.


Secobarbital-mediated inactivation of cytochrome P450 2B1 and its active site mutants. Partitioning between heme and protein alkylation and epoxidation.
He K, He YA, Szklarz GD, Halpert JR, Correia MA.
J Biol Chem. 1996;271(42):25864-25872.


Interconversion of the androstenedione hydroxylase specificities of cytochromes P450 2B4 and 2B5 upon simultaneous site-directed mutagenesis of four key substrate recognition residues.
He YQ, Szklarz GD, Halpert JR.
Arch Biochem Biophys. 1996;335(1):152-160.


Overpowering the crankshaft mechanism. The effect of posterior spinal fusion with and without stiff transpedicular fixation on anterior spinal column growth in immature canines.
Kioschos HC, Asher MA, Lark RG, Harner EJ.
Spine (Phila Pa 1976). 1996;21(10):1168-1173.


Oligonucleotide targeting to alveolar macrophages by mannose receptor-mediated endocytosis.
Liang WW, Shi XL, Deshpande D, Malanga CJ, Rojanasakul Y.
Biochim Biophys Acta. 1996;1279(2):227-234.


Protection against oxidative injury and permeability alteration in cultured alveolar epithelium by transferrin-catalase conjugate.
Rojanasakul Y, Shi XL, Deshpande D, Liang WW, Wang LY.
Biochim Biophys Acta. 1996;1315(1):21-28.


Inhaled isobutyl nitrite produced lung inflammation with increased macrophage TNF-alpha and nitric oxide production.
Soderberg LS, Chang LW, Barnett JB.
Adv Exp Med Biol. 1996;402:187-189.


Acute inhalation exposure to isobutyl nitrite causes nonspecific blood cell destruction.
Soderberg LS, Flick JT, Barnett JB.
Exp Hematol. 1996;24(5):592-596.


Elevated TNF-alpha and inducible nitric oxide production by alveolar macrophages after exposure to a nitrite inhalant.
Soderberg LS, Chang LW, Barnett JB.
J Leukoc Biol. 1996;60(4):459-464.


Leukopenia and altered hematopoietic activity in mice exposed to the abused inhalant, isobutyl nitrite.
Soderberg LS, Flick JT, Barnett JB.
Exp Hematol. 1996;24(7):848-853.


Elucidation of amino acid residues critical for unique activities of rabbit cytochrome P450 2B5 using hybrid enzymes and reciprocal site-directed mutagenesis with rabbit cytochrome P450 2B4.
Szklarz GD, He YQ, Kedzie KM, Halpert JR, Burnett VL.
Arch Biochem Biophys. 1996;327(2):308-318.


Modification of alveolar macrophage function with bis-basic ethers of fluorene and fluoren-9-substituted derivatives.
Ma JY, Cheng YH, Barger MW, Xin WF, Lewis DM, Castranova V, Ma JK.
Exp Lung Res. 1995;21(5):771-790.


Antioxidant activity of tetrandrine and its inhibition of quartz-induced lipid peroxidation.
Shi X, Mao Y, Saffiotti U, Wang LY, Rojanasakul Y, Leonard SS, Vallyathan V.
J Toxicol Environ Health. 1995;46(2):233-248.


Possible mechanisms of immunotoxicity following in vivo exposure to the inhalant, isobutyl nitrite.
Soderberg LS, Barnett JB.
Adv Exp Med Biol. 1995;373:189-192.


Inhalation exposure to isobutyl nitrite inhibits macrophage tumoricidal activity and modulates inducible nitric oxide.
Soderberg LS, Barnett JB.
J Leukoc Biol. 1995;57(1):135-140.


Impacts of mercury on Benthic invertebrate populations and communities within the aquatic ecosystem of Clear Lake, California.
Suchanek TH, Richerson PJ, Holts LJ, Lamphere BA, Woodmansee CE, Slotton DG, Harner EJ, Woodward LA.
Water Air Soil Poll. 1995;80(1-4):951-960.


Site-directed mutagenesis as a tool for molecular modeling of cytochrome P450 2B1.
Szklarz GD, He YA, Halpert JR.
Biochemistry. 1995;34(44):14312-14322.


Changes in primary and secondary lymphoid organ T-cell subpopulations resulting from acute in vivo exposure to propanil.
Zhao W, Schafer R, Cuff CF, Gandy J, Barnett JB.
J Toxicol Environ Health. 1995;46(2):171-181.


Fluoromicroscopic studies of bleomycin-induced intracellular oxidation in alveolar macrophages and its inhibition by taurine.
Bhat M, Rojanasakul Y, Weber SL, Ma JY, Castranova V, Banks DE, Ma JK.
Environ Health Perspect. 1994;102 Suppl 10:91-96.

PMC1567002.

The mitochondrial environment is required for activity of the cholesterol side-chain cleavage enzyme, cytochrome P450scc.
Black SM, Harikrishna JA, Szklarz GD, Miller WL.
Proc Natl Acad Sci USA. 1994;91(15):7247-7251.

PMC44376.

Intratracheal instillation of silica up-regulates inducible nitric oxide synthase gene expression and increases nitric oxide production in alveolar macrophages and neutrophils.
Blackford JA, Antonini JM, Castranova V, Dey RD.
Am J Respir Cell Mol Biol. 1994;11(4):426-431.


Gender-specific effects of prenatal chlordane exposure on myeloid cell development.
Blyler G, Landreth KS, Barnett JB.
Fundam Appl Toxicol. 1994;23(2):188-193.


Selective myelotoxicity of propanil.
Blyler G, Landreth KS, Lillis T, Schafer R, Theus SA, Gandy J, Barnett JB.
Fundam Appl Toxicol. 1994;22(4):505-510.


Receptor-mediated peptide delivery in pulmonary epithelial monolayers.
Deshpande D, Toledo-Velasquez D, Wang LY, Malanga CJ, Ma JK, Rojanasakul Y.
Pharm Res. 1994;11(8):1121-1126.


One-electron reduction of vanadate by ascorbate and related free radical generation at physiological pH.
Ding M, Gannett PM, Rojanasakul Y, Liu K, Shi XL.
J Inorg Biochem. 1994;55(2):101-112.


Novel delivery of antioxidant enzyme catalase to alveolar macrophages by Fc receptor-mediated endocytosis.
Harrison J, Shi XL, Wang LY, Ma JK, Rojanasakul Y.
Pharm Res. 1994;11(8):1110-1114.


Site-directed mutagenesis of putative substrate recognition sites in cytochrome P450 2B11: importance of amino acid residues 114, 290, and 363 for substrate specificity.
Hasler JA, Harlow GR, Szklarz GD, John GH, Kedzie KM, Burnett VL, He YA, Kaminsky LS, Halpert JR.
Mol Pharmacol. 1994;46(2):338-345.


Phenotypic differences among morphologically similar small-cell carcinomas detected with a panel of monoclonal antibodies and indirect immunofluorescence and flow cytometry.
Koros AM, Bey EA, Conley SL, Rogers BW.
Int J Cancer Suppl. 1994;8:127-131.


Physiologic status, coping, and hardiness as predictors of outcomes in chronic obstructive pulmonary disease.
Narsavage GL, Weaver TE.
Nurs Res. 1994;43(2):90-94.


Targeted gene delivery to alveolar macrophages via Fc receptor-mediated endocytosis.
Rojanasakul Y, Wang LY, Malanga CJ, Ma JK, Liaw J.
Pharm Res. 1994;11(12):1731-1736.


Reaction of Cr(VI) with ascorbate and hydrogen peroxide generates hydroxyl radicals and causes DNA damage: role of a Cr(IV)-mediated Fenton-like reaction.
Shi X, Mao Y, Knapton AD, Ding M, Rojanasakul Y, Gannett PM, Dalal NS, Liu K.
Carcinogenesis. 1994;15(11):2475-2478.


Generation of thiyl and ascorbyl radicals in the reaction of peroxynitrite with thiols and ascorbate at physiological pH.
Shi X, Rojanasakul Y, Gannett PM, Liu K, Mao Y, Daniel LN, Ahmed N, Saffiotti U.
J Inorg Biochem. 1994;56(2):77-86.


Application of 3-dimensional homology modeling of cytochrome P450 2B1 for interpretation of site-directed mutagenesis results.
Szklarz GD, Ornstein RL, Halpert JR.
J Biomol Struct Dyn. 1994;12(1):061-078.


Alveolar permeability enhancement by oleic acid and related fatty acids: evidence for a calcium-dependent mechanism.
Wang LY, Ma JK, Pan WF, Toledo-Velasquez D, Malanga CJ, Rojanasakul Y.
Pharm Res. 1994;11(4):513-517.


Regulation of tight junction permeability by calcium mediators and cell cytoskeleton in rabbit tracheal epithelium.
Bhat M, Toledo-Velasquez D, Wang LY, Malanga CJ, Ma JK, Rojanasakul Y.
Pharm Res. 1993;10(7):991-997.


Regulation of proteins in the cholesterol side-chain cleavage system in JEG-3 and Y-1 cells.
Black SM, Szklarz GD, Harikrishna JA, Lin D, Wolf CR, Miller WL.
Endocrinology. 1993;132(2):539-545.


Experimental comparisons in petroleum site bioremediation.
Blackburn JW, Robbins WK, Prince RC, Harner EJ, Clark JR, Atlas RM, Wilkinson JB.
Abstr Pap Am Chem S. 1993;205:75-ETR.


Monitoring and interpreting bioremediation effectiveness.
Bragg JR, Prince RC, Harner EJ, Atlas RM.
Abstr Pap Am Chem S. 1993;205:65-ETR.


Exposure of rats to hyperoxia: alteration of lavagate parameters and macrophage function.
Dedhia HV, Ma JY, Vallyathan V, Dalal NS, Banks DE, Flink EB, Billie M, Barger MW, Castranova V.
J Toxicol Environ Health. 1993;40(1):1-13.


Organic dust exposure from compost handling: response of an animal model.
Frazer DG, Jones WG, Petsonk EL, Kullman GJ, Barger MW, Afshari A, Jones T, Castranova V.
Am J Ind Med. 1993;24(4):375-385.


Construction and function of fusion enzymes of the human cytochrome P450scc system.
Harikrishna JA, Black SM, Szklarz GD, Miller WL.
DNA Cell Biol. 1993;12(5):371-379.


Inhibition of proliferative activity of pulmonary fibroblasts by tetrandrine.
Reist RH, Dey RD, Durham JP, Rojanasakul Y, Castranova V.
Toxicol Appl Pharmacol. 1993;122(1):70-76.


Altered calcium homeostasis and cell injury in silica-exposed alveolar macrophages.
Rojanasakul Y, Wang LY, Malanga CJ, Ma JY, Banks DE, Ma JK.
J Cell Physiol. 1993;154(2):310-316.


Mechanisms of hydroxyl free radical-induced cellular injury and calcium overloading in alveolar macrophages.
Rojanasakul Y, Wang LY, Hoffman AH, Shi XL, Dalal NS, Banks DE, Ma JK.
Am J Respir Cell Mol Biol. 1993;8(4):377-383.


Exposure to the abused inhalant, isobutyl nitrite, compromises both antibody and cell-mediated immunity.
Soderberg LS, Barnett JB.
Adv Exp Med Biol. 1993;335:265-268.


Inhaled isobutyl nitrite compromises T-dependent, but not T-independent, antibody induction.
Soderberg LS, Barnett JB.
Int J Immunopharmacol. 1993;15(7):821-827.


Alteration of macrophage cytotoxicity through endogenous interferon and tumor necrosis factor alpha induction by propanil.
Theus SA, Tabor DR, Gandy J, Barnett JB.
Toxicol Appl Pharmacol. 1993;118(1):46-52.


Transport and hydrolysis of enkephalins in cultured alveolar epithelial monolayers.
Wang LY, Toledo-Velasquez D, Schwegler-Berry D, Ma JK, Rojanasakul Y.
Pharm Res. 1993;10(11):1662-1667.


Comparison of the immunotoxicity of propanil and its metabolite, 3,4-dichloroaniline, in C57Bl/6 mice.
Barnett JB, Gandy J, Wilbourn D, Theus SA.
Fundam Appl Toxicol. 1992;18(4):628-631.


Inhibitory action of tetrandrine on macrophage production of interleukin-1 (IL-1)-like activity and thymocyte proliferation.
Kang JH, Lewis DM, Castranova V, Rojanasakul Y, Banks DE, Ma JY, Ma JK.
Exp Lung Res. 1992;18(5):715-729.


Cytokine regulation of bone marrow natural suppressor cell activity in the suppression of lymphocyte function.
Moore SC, Theus SA, Barnett JB, Soderberg LS.
Cell Immunol. 1992;141(2):398-408.


Bone marrow natural suppressor cells inhibit the growth of myeloid progenitor cells and the synthesis of colony-stimulating factors.
Moore SC, Theus SA, Barnett JB, Soderberg LS.
Exp Hematol. 1992;20(10):1178-1183.


The transport barrier of epithelia: a comparative study on membrane permeability and charge selectivity in the rabbit.
Rojanasakul Y, Wang LY, Bhat M, Glover DD, Malanga CJ, Ma JK.
Pharm Res. 1992;9(8):1029-1034.


In vivo prenatal chlordane exposure induces development of endogenous inflammatory macrophages.
Theus SA, Lau KA, Tabor DR, Soderberg LS, Barnett JB.
J Leukoc Biol. 1992;51(4):366-372.


Macrophage tumoricidal mechanisms are selectively altered by prenatal chlordane exposure.
Theus SA, Tabor DR, Soderberg LS, Barnett JB.
Agents Actions. 1992;37(1-2):140-146.


Physiological and psychological variables related to functional status in chronic obstructive pulmonary disease.
Weaver TE, Narsavage GL.
Nurs Res. 1992;41(5):286-291.


Effects of bisbenzylisoquinoline alkaloids on alveolar macrophages: correlation between binding affinity, inhibitory potency, and antifibrotic potential.
Castranova V, Kang JH, Ma JK, Mo CG, Malanga CJ, Moore MD, Schwegler-Berry D, Ma JY.
Toxicol Appl Pharmacol. 1991;108(2):242-252.


Binding of bisbenzylisoquinoline alkaloids to phosphatidylcholine vesicles and alveolar macrophages: relationship between binding affinity and antifibrogenic potential of these drugs.
Ma JK, Mo CG, Malanga CJ, Ma JY, Castranova V.
Exp Lung Res. 1991;17(6):1061-1077.


Exposure to inhaled isobutyl nitrite reduces T cell blastogenesis and antibody responsiveness.
Soderberg LS, Barnett JB.
Fundam Appl Toxicol. 1991;17(4):821-824.


Inhaled isobutyl nitrite impairs T cell reactivity.
Soderberg LS, Barnett JB, Chang LW.
Adv Exp Med Biol. 1991;288:265-268.


Long-term alteration of adult bone marrow colony formation by prenatal chlordane exposure.
Barnett JB, Blaylock BL, Gandy J, Menna JH, Denton R, Soderberg LS.
Fundam Appl Toxicol. 1990;14(4):688-695.


Alteration of fetal liver colony formation by prenatal chlordane exposure.
Barnett JB, Blaylock BL, Gandy J, Menna JH, Denton R, Soderberg LS.
Fundam Appl Toxicol. 1990;15(4):820-822.


Cytotoxic T-lymphocyte and NK responses in mice treated prenatally with chlordane.
Blaylock BL, Soderberg LS, Gandy J, Menna JH, Denton R, Barnett JB.
Toxicol Lett. 1990;51(1):41-49.


Postirradiation treatment with copper(II)2(3,5-diisopropylsalicylate)4 enhances radiation recovery and hemopoietic regeneration.
Soderberg LS, Barnett JB, Baker ML, Salari H, Sorenson JR.
Exp Hematol. 1990;18(7):801-805.


Radiation recovery agents: Cu(II), Mn(II), Zn(II), or Fe(III) 3,5-diisopropylsalicylate complexes facilitate recovery from ionizing radiation induced radical mediated tissue damage.
Sorenson JJ, Soderberg LS, Baker ML, Barnett JB, Chang LW, Salari H, Willingham WM.
Adv Exp Med Biol. 1990;264:69-77.


Effect of acute propanil exposure on the immune response of C57Bl/6 mice.
Barnett JB, Gandy J.
Fundam Appl Toxicol. 1989;12(4):757-764.


Copper complexes stimulate hemopoiesis and lymphopoiesis.
Soderberg LS, Barnett JB, Sorenson JR.
Adv Exp Med Biol. 1989;258:209-217.


Immunohistochemical detection of steroid binding in rabbit cornea.
Rojanasakul Y, Robinson JR.
J Ocul Pharmacol. 1988;4(1):51-60.


Copper(II)2(3,5-diisopropylsalicylate)4 stimulates hemopoiesis in normal and irradiated mice.
Soderberg LS, Barnett JB, Baker ML, Chang LW, Salari H, Sorenson JR.
Exp Hematol. 1988;16(7):577-580.


Generation of free radicals from freshly fractured silica dust. Potential role in acute silica-induced lung injury.
Vallyathan V, Shi XL, Dalal NS, Irr W, Castranova V.
Am Rev Respir Dis. 1988;138(5):1213-1219.


The effect of in utero exposure to hexachlorobenzene on the developing immune response of BALB/c mice.
Barnett JB, Barfield L, Walls R, Joyner R, Owens R, Soderberg LS.
Toxicol Lett. 1987;39(2-3):263-274.


Copper(II)(3,5-diisopropylsalicylate)2 accelerates recovery of B and T cell reactivity following irradiation.
Soderberg LS, Barnett JB, Baker ML, Salari H, Sorenson RJ.
Scand J Immunol. 1987;26(5):495-502.


The effect of prenatal chlordane exposure on the delayed hypersensitivity response of BALB/c mice.
Barnett JB, Soderberg LS, Menna JH.
Toxicol Lett. 1985;25(2):173-183.


The effect of prenatal chlordane exposure on specific anti-influenza cell-mediated immunity.
Barnett JB, Holcomb D, Menna JH, Soderberg LS.
Toxicol Lett. 1985;25(3):229-238.


Methyl-bromide eradication of the Oak Wilt Fungus from red and white oak logs.
Macdonald WL, Schmidt EL, Harner EJ.
Forest Prod J. 1985;35(7-8):11-16.


Influenza type A virus infection of mice exposed in utero to chlordane; survival and antibody studies.
Menna JH, Barnett JB, Soderberg LS.
Toxicol Lett. 1985;24(1):45-52.


Biomass predicted by soil-site factors - A case-study in North Central West-Virginia.
Frank PS, Hicks RR, Harner EJ.
Can J Forest Res. 1984;14(1):137-140.


Use of pressurized vials for loading sample loops in soil gas-analyses.
Staley TE, Hern JL, Harner EJ.
Soil Sci Soc Am J. 1984;48(5):1201-1202.


Survival of the Oak Wilt Fungus in air-dried lumber.
Tainter FH, Macdonald WL, Harner EJ.
Eur J Forest Pathol. 1984;14(1):9-16.


Osteoarthrosis: sex-specific relationship to osteoporosis.
Burr DB, Martin RB, Schaffler MB, Jurmain RD, Harner EJ, Radin EL.
Am J Phys Anthropol. 1983;61(3):299-303.


Cultural-characteristics, pathogenicity predictions, and pathogenicity tests for some isolates of Ceratocystis-Ulmi.
Hindal DF, Harner EJ, Macdonald WL.
Can J Bot. 1981;59(12):2543-2549.


Identifying medical regions using hierarchical clustering.
Harner EJ, Slater PB.
Soc Sci Med. 1980;14D(1):3-10.


Predicting root age of advance growth beneath hardwood canopies.
Tryon EH, Powell DS, Harner EJ.
Can J Forest Res. 1980;10(3):264-268.


Further-studies on the relationship between cultural-characteristics and pathogenicity in Ceratocystis-Ulmi.
Hindal DF, Harner EJ, Macdonald WL.
Phytopathology. 1979;69(2):108-111.


Percent bias and standard error in logarithmic regression.
Wiant HV, Harner EJ.
Forest Sci. 1979;25(1):167-168.


Effects of freeze-preservation on some pollen enzymes. II. Freezing and freeze-drying stresses.
Anderson JO, Nath J, Harner EJ.
Cryobiology. 1978;15(4):469-477.


Multivariate measures of niche overlap using discriminant analysis.
Harner EJ, Whitmore RC.
Theor Popul Biol. 1977;12(1):21-36.


Analysis of a 12-Year corn-small grain rotation experiment at 4 fertility levels.
Harner EJ, Pohlman GG, Sperow CB.
Agronomy Journal. 1977;69(6):988-994.